Gout

Gout yog ib hom mob caj dab. Nws tshwm sim thaum uric acid tsim kev rau hauv cov ntshav thiab ua rau mob hauv cov pob qij txha.

Mob gout yog mob mob uas feem ntau cuam tshuam tsuas yog ib leeg. Mob gout yog mob pheej rov ua mob thiab mob ntxiv. Ntau tshaj ib qho kev sib koom yuav raug cuam tshuam.

Mob Gout yog tshwm sim los ntawm muaj ntau dua-tshaj li ib txwm muaj ntawm uric acid hauv koj lub cev. Qhov no yuav tshwm sim yog tias:

• Koj lub cev ua rau cov uric acid ntau dhau
• Koj lub cev muaj kev nyuaj los daws cov mob uric acid

Thaum uric acid tsim cov kua dej nyob ib ncig ntawm cov pob qij txha (kua dej synovial), uric acid crystals form. Cov iav no ua rau qhov sib koom ua ke ua rau mob, ua rau mob, o thiab sov.

Vim li cas tiag tsis muaj neeg paub. Gout yuav khiav hauv tsev neeg. Qhov teeb meem no tshwm sim rau cov txiv neej, rau poj niam tom qab lawm, thiab cov neeg uas haus cawv. Raws li cov neeg muaj hnub nyoog, gout ua ntau dua.

Tus mob kuj tseem tuaj yeem tsim hauv tib neeg nrog:

• Mob ntshav qab zib
• Mob raum
• Kev pham
• Sickle cell anemia thiab lwm yam anemias
• Ntshav mob ntshav thiab lwm cov ntshav qog nqaij hlav

Gout yuav tshwm sim tom qab noj tshuaj uas cuam tshuam nrog kev tshem tawm uric acid los ntawm lub cev. Cov neeg uas noj qee yam tshuaj, xws li hydrochlorothiazide thiab lwm yam dej tshuaj, tej zaum yuav muaj ntau dua uric acid hauv cov ntshav.

Cov tsos mob ntawm tus mob gout:

• Feem ntau, tsuas yog ib lossis ob peb pob qij txha raug cuam tshuam. Lub pob taw loj, lub hauv caug lossis pob taws pob qij txha feem ntau cuam tshuam. Qee zaum ntau cov pob qij txha o tuaj yeem o thiab mob.
• Qhov mob pib dheev, feem ntau thaum hmo ntuj. Mob yog feem ntau mob hnyav, piav raws li throbbing, tsoo, lossis tawm.
• Qhov sib koom tes tshwm sov thiab liab. Nws feem ntau nws tau mos thiab o (nws mob los ua ib daim pam los yog pam vov nws).
• Tej zaum nws yuav muaj kub cev.
• Qhov kev tawm tsam no yuav ploj mus nyob rau ob peb hnub, tab sis tuaj yeem rov qab los ntawm ib lub sijhawm. Cov kev tawm tsam ntxiv feem ntau nyob ntev.

Qhov mob thiab o feem ntau ploj mus tom qab thawj zaug tua. Coob leej ntau tus yuav muaj lwm qhov kev tawm tsam 6 rau 12 lub hlis tom ntej.

Qee tus neeg yuav pib mob gout. Qhov no tseem hu ua kev mob caj dab gouty. Tus mob no tuaj yeem ua rau kev sib koom tes ua kom lub cev thiab ploj hauv cov pob qij txha. Cov neeg muaj tus mob gout yuav muaj mob ua ke thiab muaj lwm cov tsos mob feem ntau.

Cov xau ntawm uric acid tuaj yeem ua rau hauv qab cov tawv nqaij puag ncig cov pob qij txha lossis lwm qhov chaw xws li lauj tshib, ntiv tes, thiab pob ntseg. Cov pob zeb hu ua lub tophus, los ntawm Latin, txhais tau hais tias ib hom pob zeb. Tophi (ntau cov leeg) tuaj yeem txhim kho tom qab ib tus neeg mob gout tau ntau xyoo. Cov pob no yuav ua rau cov khoom chalky ploj.

Kev ntsuam xyuas uas yuav ua tau muaj xws li:

• Kev soj ntsuam cov kua dej (qhia uric acid muaju)
• Uric acid - ntshav
• Mob xoo hluav taws xob (tej zaum yuav zoo li no)
• Synovial me me
• Uric acid - zis

Qib uric acid nyob rau hauv cov ntshav dhau 7 mg / dL (milligrams per deciliter) yog siab heev. Tab sis, tsis yog txhua tus neeg muaj uric acid siab muaj gout.

Noj tshuaj rau mob gout kom sai li sai tau yog tias koj muaj qhov tshiab tawm tsam.

Noj nonsteroidal anti-inflammatory tshuaj (NSAIDs) xws li ibuprofen lossis indomethacin thaum cov tsos mob pib. Tham nrog koj tus kws kho mob txog kev muab tshuaj kom raug. Koj yuav tsum tau txhaj tshuaj ntau dua nyob rau ob peb hnub.

• Cov tshuaj uas hu ua colchicine pab txo qhov mob, o, thiab o.
• Corticosteroids (xws li prednisone) kuj tseem tuaj yeem ua tau haujlwm zoo. Koj tus kws kho mob tuaj yeem txhaj tshuaj sib txuas nrog cov tshuaj steroids txhawm rau txo qhov mob.
• Nrog kev tawm tsam gout nyob rau ntau lub pob qij txha ib cov tshuaj hu ua anakinra (Kineret) siv tau.
• Qhov mob feem ntau ploj mus li ntawm 12 teev tom qab pib kho mob. Feem ntau, txhua qhov mob yuav ploj mus nyob hauv 48 teev.

Koj yuav tsum tau noj tshuaj txhua hnub xws li allopurinol (Zyloprim), febuxostat (Uloric) lossis probenecid (Benemid) kom txo qis uric acid qib hauv koj cov ntshav. Txo cov tshuaj uric acid kom tsawg dua 6 mg / dL xav tau los tiv thaiv qhov tso nyiaj ntawm uric acid. Yog tias koj tau pom muaj tophi, uric acid yuav tsum qis dua 5 mg / dL.

Koj yuav xav tau cov tshuaj no yog hais tias:

• Koj muaj ntau qhov kev tawm tsam nyob rau tib lub xyoo lossis koj cov kev tawm tsam hnyav heev.
• Koj muaj kev puas tsuaj pob qij txha.
• Koj yuav tsum tophi.
• Koj muaj raum mob raum los yog lub raum.

Kev noj zaub mov kom lub cev thiab lub neej hloov pauv tuaj yeem pab tiv thaiv kom tsis txhob muaj gouty:

• Txo qhov haus dej haus cawv, tshwj xeeb tshaj yog npias (qee tus cawv kuj yuav pab tau).
• Poob phaus.
• Kev tawm dag zog txhua hnub.
• Txwv txiav koj kev noj cov nqaij liab thiab cov dej qab zib.
• Xaiv cov zaub mov muaj txiaj ntsig zoo, xws li khoom noj siv mis, zaub, txiv ntoo, khoom noj, txiv hmab txiv ntoo (muaj suab thaj tsawg dua), thiab cov nplej ntau.
• Cov pab kas fes thiab vitamin C ntxiv (tej zaum yuav pab tau qee tus neeg).

Kev kho kom zoo ntawm cov kev mob hnyav thiab txo qis uric acid kom tsawg dua 6 mg / dL pub rau tib neeg ua lub neej zoo. Txawm li cas los xij, cov mob hnyav ntawm tus kab mob no tuaj yeem hloov mus rau mob gout yog tias muaj qhov siab uric acid tsis tau kho txaus.

Teeb meem yuav suav nrog:

• Mob caj dab gouty mob caj dab.
• Raum pob zeb.
• Kev tso cia rau hauv lub raum, ua rau lub raum tsis ua haujlwm lawm.

Theem ntau ntawm uric acid nyob rau hauv cov ntshav yog cuam tshuam nrog kev pheej hmoo rau mob raum. Cov kev tshawb fawb tab tom tshawb nrhiav seb puas txo qis uric acid txo qhov kev pheej hmoo rau mob raum.

Hu rau koj tus kws kho mob yog tias koj muaj cov tsos mob ntawm tus mob gouty mob caj dab lossis yog tias koj mob tophi.

Koj yuav tsis tuaj yeem tiv thaiv qhov mob gout, tab sis koj yuav tuaj yeem zam qhov uas ua rau cov tsos mob tshwm sim. Noj tshuaj kom txo tau cov mob uric acid tuaj yeem tiv thaiv qhov mob gout. Ntev mus, koj qhov kev tso tawm ntawm uric acid yuav ploj mus.

Gouty mob caj dab - mob heev; Gout - mob hnyav; Hyperuricemia; Thaub qab gout; Tophi; Podagra; Gout - mob ntev; Mob caj dab ntev; Mob hnyav gout; Mob caj dab mob caj dab ntev

• Lub raum pob zeb thiab lithotripsy - kev tshem tawm
• Raum pob zeb - kev saib xyuas tus kheej
• Lub raum pob zeb - dab tsi yuav tsum nug koj tus kws kho mob
• Cov kab mob tso zis ntau dhau - tso tawm

• Uric acid muaju
• Tophi gout nyob rau hauv tes

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Edwards NL. Crystal deposition kab mob. Hauv: Goldman L, Schafer AI, eds. Goldman-Cecil TshuajCov. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: chap 273.

FitzGerald JD, Neogi T, Choi HK. Kev kho: tsis txhob cia gout apathy ua rau gouty arthropathy. Mob Pob Txha RheumatolCov. 2017; 69 (3): 479-482. PMID: 28002890 www.ncbi.nlm.nih.gov/pubmed/28002890.

Khanna D, Fitzgerald JD, Khanna PP, li al. 2012 American College of Rheumatology cov lus qhia rau kev tswj hwm gout. Tshooj 1: cov kab ke tsis muaj kev ua kom tsis raug mob thiab kev siv tshuaj kho mob kom ua rau hyperuricemia. Mob caj dab los tu Res (Hoboken)Cov. Xyoo 2012; 64 (10): 1431-1446. PMID: 23024028 www.ncbi.nlm.nih.gov/pubmed/23024028.

Khanna D, Khanna PP, Fitzgerald JD, li al. 2012 American College of Rheumatology cov lus qhia rau kev tswj hwm gout. Qhov 2: kev kho thiab antiinflammatory prophylaxis ntawm mob gouty mob caj dab. Mob caj dab los tu Res (Hoboken)Cov. 2012; 64 (10): 1447-1461. PMID: 23024029 www.ncbi.nlm.nih.gov/pubmed/23024029.

Liew JW, Gardner GC. Kev siv ntawm anakinra hauv cov neeg mob hauv tsev kho mob nrog cov pob qij txha ntsig txog kev mob caj dab. J RheumatolCov. 2019 pii: jrheum.181018. [Epub ua ntej sau]. PMID: 30647192 www.ncbi.nlm.nih.gov/m/pubmed/30647192.