Tus Sau: Eugene Taylor
Hnub Kev Tsim: 16 Lub Yim Hli Ntuj 2021
Hloov Hnub: 20 Lub Cuaj Hli Ntuj 2024
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How to Inject Taltz
Daim Duab: How to Inject Taltz

Zoo Siab

Taltz yog dab tsi?

Taltz yog ib hom tshuaj muaj npe muab tshuaj. Nws raug pom zoo los kho cov mob hauv qab no:

Rau cov quav hniav mob psoriasis, Taltz tuaj yeem raug kho rau cov neeg laus thiab menyuam hnub nyoog 6 xyoo thiab laus dua. Tab sis rau txhua qhov ntawm lwm qhov kev pom zoo siv, Taltz tuaj yeem tsuas yog kho rau cov laus xwb.


Taltz muaj cov tshuaj tseem ceeb ixekizumab. Nws yog hom tshuaj khomob biologic (cov tshuaj tsim los ntawm cov ciaj sia hauv hlwb) hu ua human monoclonal antibody.

Taltz los ua ob hom: ib rab koob prefilled thiab tus cwj mem autoinjector. Cov tshuaj yog muab los ntawm kev txhaj tshuaj hauv qab koj cov tawv nqaij (txhaj tshuaj subcutaneous). Koj tus kws kho mob yuav muab kev txhaj tshuaj rau koj thaum xub thawj. Tom qab ntawd lawv tuaj yeem qhia koj yuav ua li cas txhaj tshuaj rau koj tus kheej hauv tsev.

Txij nkawm

Txog cov ntaub ntawv hais txog Taltz kev ua tau zoo hauv kev kho cov mob uas tau teev saud, saib hauv seem "Taltz siv" hauv qab no.

Taltz feem ntau

Taltz tsuas yog muaj raws li muaj koob npe tshuaj rau kev noj kev haus. Tam sim no nws tsis muaj cov qauv tsis tu ncua. (Ib qho tshuaj feem ntau yog ib daim qauv meej ntawm cov tshuaj nquag nyob hauv cov tshuaj muaj npe lag luam.)

Taltz muaj ib yam tshuaj ua muaj tshuaj: ixekizumab.

Taltz ntau npaum

Lub koob tshuaj Taltz uas koj tus kws kho mob sau ntawv yuav yog nyob ntawm qhov raug kho.

Cov ntaub ntawv hauv qab no piav qhia ntau npaum li cas cov tshuaj uas feem ntau siv los yog ua kom siv. Txawm li cas los xij, nco ntsoov siv qhov ntau thiab ua raws lub sijhawm noj tshuaj uas koj tus kws kho mob tau sau ntawv rau koj.


Cov ntaub ntawv tshuaj thiab qhov ua tau zoo

Taltz muaj nyob rau hauv ib qho zog: 80 milligrams ib milliliter (mg / mL).

Cov tshuaj muaj ob hom: ib leeg siv ib leeg tshuaj pleev ib ce thiab ib leeg siv cov tshuaj pleev autoinjector cwj mem. Koj tuaj yeem pom tias ib daim foos yooj yim rau koj siv dua lwm daim. Tham nrog koj tus kws kho mob txog daim ntawv twg zoo tshaj rau koj.

Cov tshuaj yog muab los ntawm kev txhaj tshuaj hauv qab koj cov tawv nqaij (txhaj tshuaj subcutaneous). Koj tus kws kho mob yuav muab kev txhaj tshuaj rau koj thaum xub thawj. Tom qab ntawd lawv tuaj yeem qhia koj yuav ua li cas txhaj tshuaj rau koj tus kheej hauv tsev.

Tsuas tshuaj rau cov mob caj dab psoriatic

Rau cov mob caj dab psoriatic mob, koj thawj koob tshuaj Taltz yuav raug muab raws li ob koob 80-mg txhaj tshuaj (rau tag nrho 160 mg) rau tib hnub. Tom qab ntawd, koj cov tshuaj kho kom haum yuav yog ib 80-mg txhaj ib zaug txhua 4 lub lis piam kom ntev li ntev tau uas koj tus kws kho mob pom zoo.

Nco tseg: Yog xav paub ntxiv txog kev mob caj dab, saib tshooj “Kev Siv Taltz” hauv qab no.

Dosage rau mob hnyav rau qhov cov quav hniav psoriasis

Txog cov quav hniav psoriasis, koj thawj koob Taltz yuav yog ob koob 80-mg (rau tag nrho 160 mg) rau tib hnub. Tom qab ntawd, koj yuav tau txhaj ib koob 80-mg ib zaug txhua 2 lub lis piam rau 12 lub lis piam. Tom qab ntawd koj cov tshuaj saib xyuas yuav yog ib koob ib zaug txhua 4 lub lis piam kom ntev li ntev tau koj tus kws kho mob pom zoo.


Nco tseg: Yog xav paub ntau ntxiv txog cov quav hniav psoriasis, saib rau seem “Taltz siv” ntu hauv qab no.

Koob tshuaj rau mob caj dab psoriatic thiab mob me mus rau qhov quav hniav psoriasis

Yog tias koj muaj mob ob leeg mob psoriatic thiab mob pliav liab, koj yuav tau siv Taltz ntau npaum li cas thiab noj tshuaj ntau npaum li cas rau mob qog mob ntshav siab. Saib tshooj lus saum toj no nkaus xwb kom paub txog qhov no.

Nco tseg: Yog xav paub ntau ntxiv txog kev muaj kev mob caj dab thiab mob plaw liab, saib tshooj “Taltz siv” hauv qab no.

Dosage rau tsis-radiographic axial spondyloarthritis

Txog qhov tsis muaj radiographical axial spondyloarthritis (nr-axSpA), koj yuav tau txais 80-mg txhaj ntawm Taltz ib zaug txhua 4 lub lis piam.

Nco tseg: Yog xav paub ntxiv txog nr-axSpA, saib tshooj “Taltz siv” ntu hauv qab no.

Tsuas tshuaj rau kom nquag plob ankylosing spondylitis

Txog ankylosing spondylitis (AS), koj thawj koob Taltz yuav yog ob koob 80-mg (rau tag nrho 160 mg) rau tib hnub. Tom qab ntawd, koj cov kev saib xyuas txij nkawm yuav yog 80-mg txhaj ib zaug txhua 4 lub lis piam.

Nco tseg: Xav paub ntau ntxiv txog AS, saib tshooj “Taltz siv” ntu hauv qab no.

Yog tias kuv plam koob tshuaj?

Yog tias koj plam kev txhaj tshuaj, koj yuav tsum muaj nws sai li sai tau. Tom qab ntawd cia li siv koj txoj kev txhaj tshuaj ntxiv thaum nws ib txwm ua tiav lawm. Tab sis yog tias koj plam kev txhaj tshuaj thiab nws tsis ntev txog thaum koj txoj kev xav txuas ntxiv, nug koj tus kws kho mob kom pab tswv yim.

Txhawm rau kom paub tseeb tias koj tsis nco nco ib koob, sim teem kev ceeb toom rau koj lub xov tooj. Ib lub sijhawm muab tshuaj yuav yog ib qho zoo, ib yam nkaus.

Kuv puas yuav tau siv cov tshuaj no ntev?

Taltz yog txhais tau tias siv los ua kev kho mob ntev. Yog tias koj thiab koj tus kws kho mob txiav txim siab tias Taltz ua haujlwm zoo rau koj, nws zoo li koj yuav siv nws mus ntev.

Taltz phiv

Taltz tuaj yeem ua rau mob sab me lossis mob loj. Cov npe hauv qab no muaj qee qhov kev mob tshwm sim thaum yuav noj Taltz. Daim ntawv no tsis suav nrog tag nrho cov kev mob tshwm sim.

Yog xav paub cov ntaub ntawv ntau ntxiv txog qhov tshwm sim zoo tuaj ntawm Taltz, tham nrog koj tus kws kho mob lossis kws muag tshuaj. Lawv tuaj yeem muab cov lus qhia rau koj txog kev yuav ua li cas nrog cov kev mob tshwm sim uas tuaj yeem thab.

Nco tseg: Lub Chaw Tswj Xyuas Khoom Noj thiab Tshuaj (FDA) taug qab cov kev phiv los ntawm cov tshuaj uas nws tau pom zoo. Yog tias koj xav ceeb toom mus rau FDA txog qhov tshwm sim uas koj tau muaj nrog Taltz, koj tuaj yeem ua li ntawd dhau ntawm MedWatch.

Ntau cov kev mob tshwm sim

Cov kev phiv ntau tshaj ntawm Taltz tuaj yeem suav nrog:

  • Qhov chaw txhaj tshuaj lom (liab thiab mob ncig thaj chaw txhaj tshuaj)
  • cov kab mob sab saud, xws li tus mob khaub thuas lossis mob khaub thuas
  • xeev siab
  • mob ua npaws, yam li ncaws pob ko taw
  • mob muag (liab muag)

Feem ntau ntawm cov kev mob tshwm sim no yuav ploj mus li ntawm ob peb hnub lossis ob peb lub lis piam. Yog tias lawv mob hnyav dua lossis tsis ploj mus, nrog koj tus kws kho mob lossis kws muag tshuaj tham.

Cov kev mob tshwm sim hnyav heev

Cov kev mob tshwm sim hnyav los ntawm Taltz tsis yog tshwm sim, tab sis lawv tuaj yeem tshwm sim. Hu rau koj tus kws kho mob tam sim ntawd yog tias koj muaj kev phiv loj heev. Hu 911 yog tias koj tus mob xav tias yuav muaj teeb meem tuag taus lossis yog koj xav tias koj muaj mob xwm txheej kub ntxhov ceev.

Cov kev phiv loj heev, uas yuav piav qhia kom meej ntxiv hauv qab no hauv “Cov nyhuv cuam tshuam,” suav nrog:

  • kev fab tshuaj hnyav heev
  • cov mob ua paug plob tsis so tswj (IBD), xws li Crohn's mob lossis mob plab nyhuv
  • muaj feem ntau ntawm cov mob, xws li mob ntsws (TB)

Sab kev tshwm sim rau cov menyuam yaus

Cov kev tshawb fawb soj ntsuam xyuas cov menyuam yaus hnub nyoog 6 txog 18 xyoo uas muaj cov quav hniav mob caj pas. Hauv qhov kev tshawb fawb no, cov kev mob tshwm sim pom hauv cov menyuam yaus thiab cov uas tshwm sim heev npaum li cas tau hais txog tib yam li cov uas pom hauv cov neeg laus. Raws li kev zam rau qhov no, cov kev mob tshwm sim txuas ntxiv tshwm sim rau cov menyuam yaus ntau dua li cov neeg laus:

  • mob muag (liab muag)
  • npaws
  • khaus (ua pob khaus ntawm daim tawv nqaij)

Hauv tib txoj kev tshawb nrhiav, Crohn tus kab mob tshwm sim 0.9% ntau dua rau cov menyuam yaus noj Taltz dua li nws tshwm sim hauv cov menyuam yaus uas tau noj cov placebo. (Ib cov tshuaj placebo yog ib txoj kev kho mob uas tsis muaj tshuaj lom.)

Sab sij huam cov ntsiab lus

Tej zaum koj yuav xav paub ntau npaum li cas tej kev mob tshwm sim nrog cov tshuaj no, lossis seb puas muaj qee yam kev mob tshwm sim los cuam tshuam rau nws. Nov yog qee qhov qhia meej txog qee cov kev mob tshwm sim ntawm cov tshuaj no tuaj yeem ua lossis tsis ua.

Kev fab tshuaj tiv thaiv

Ib yam li nrog rau cov tshuaj feem ntau, qee tus neeg tuaj yeem muaj kev fab tshuaj tom qab siv Taltz. Cov tsos mob ntawm kev txhaum fab hnyav tuaj yeem suav nrog:

  • daim tawv nqaij ua pob
  • khaus
  • tso tawm (sov thiab liab nyob hauv koj cov tawv nqaij)

Ib qho kev txhaum fab hnyav dua yog muaj tsawg tab sis ua tau. Cov tsos mob ntawm kev txhaum fab hnyav tuaj yeem suav nrog:

  • Mob hlwb (o rau hauv koj daim tawv nqaij, feem ntau hauv koj daim tawv muag, daim di ncauj, lossis sab plhu)
  • o ntawm koj tus nplaig, qhov ncauj, lossis caj pas
  • teeb meem ua pa
  • hauv siab nruj
  • lawm tsaus muag

Hauv qhov kev tshawb fawb soj ntsuam, kev fab tshuaj muaj tshwm sim hauv 0.1% lossis tsawg dua ntawm cov neeg uas tau txais Taltz. Kev ua xua tshwm sim suav nrog angioedema thiab urticaria (qhov khaus khaus tawv nqaij kuj tseem hu ua khaus khaus.

Hu rau koj tus kws kho mob tam sim ntawd yog tias koj muaj qhov kev tsis haum tshuaj heev rau Taltz. Tab sis hu 911 lossis koj tus npawb xov tooj thaum muaj xwm ceev hauv zej zog yog tias koj cov tsos mob xav tias yuav ua rau tuag taus lossis yog koj xav tias koj muaj mob kub ntxhov.

Kev txhaj tshuaj ntawm qhov chaw tiv thaiv

Koj tuaj yeem muaj kev tawm tsam tawv nqaij ntawm thaj chaw uas koj txhaj koob tshuaj Taltz. Thiab cov kev tshwm sim no tuaj yeem ua rau cov tsos mob xws li liab lossis mob.

Hauv cov kev tshawb fawb soj ntsuam, 17% ntawm cov neeg muaj plaque psoriasis uas tau txais Taltz muaj qhov tshuaj tiv thaiv, xws li liab lossis mob, ntawm qhov chaw txhaj tshuaj. Feem ntau ntawm cov tshuaj tiv thaiv nws tsis mob me me los sis mob hnyav thiab tsis ua rau tib neeg txiav kev kho mob.

Txhua zaus koj txhaj Taltz, koj yuav tsum xaiv qhov chaw txawv ntawm koj lub cev dua li kev txhaj tshuaj zaum kawg. Yog tias koj muaj qhov tsis haum ntawm daim tawv nqaij uas hnyav lossis tsis ploj mus li ob peb hnub, mus ntsib koj tus kws kho mob.

Nce muaj feem yuav kis tau

Taltz tuaj yeem ua rau koj lub cev tsis muaj zog. Thaum koj lub cev tiv thaiv tsis muaj zog txaus rau tua cov kab mob, koj yuav muaj feem kis tau yooj yim dua.

Hauv kev tshawb fawb hauv tsev kho mob, 27% ntawm cov neeg muaj plaque psoriasis uas tau txais Taltz rau 12 lub lis piam tau mob sib kis. Nov yog qee qhov kev tshawb pom 'kev tshawb pom:

  • Feem ntau ntawm cov kis tau mob me. Tsuas yog 0.4% ntawm tus mob tau pom tias yog mob hnyav, xws li mob ntsws.
  • Cov kab mob uas nquag muaj tshaj yog kab mob ntsws xws li hnoos, khaub thuas, lossis mob caj pas.
  • Lwm yam kab mob suav nrog pom mob ua paug (qhov muag liab) thiab mob ua paug, xws li ntsej muag lossis mob ko taw.
  • Hauv cov kev tshawb fawb no, 23% ntawm cov tib neeg uas tau txais cov placebo (kev kho mob tsis muaj ib qho tshuaj lom) tseem muaj tus kab mob.
  • Hauv cov neeg uas tau txais kev kho mob Taltz li ntawm 60 lub lis piam, 57% tau tus kab mob piv rau 32% tus uas tau txais cov placebo.

Saib xyuas thiab tshuaj xyuas kom kis tau tus mob

Yog tias koj muaj cov tsos mob ntawm tus mob, tham nrog koj tus kws kho mob lossis kws muag tshuaj. Lawv tuaj yeem pom zoo kho mob. Cov tsos mob ntawm kev kis tus mob me tuaj yeem suav nrog:

  • ua npaws
  • hnoos
  • mob caj pas
  • liab thiab mob qhov muag
  • liab thiab mob thaj chaw ntawm daim tawv nqaij
  • dawb plia nyob rau hauv koj lub qhov ncauj
  • mob lossis mob thaum tso zis

Nws yog ib qho tseem ceeb heev rau koj mus ntsib koj tus kws kho mob yog hais tias tus kab mob tsis pom meej. Txwv tsis pub, nws tuaj yeem dhau los ua neeg loj dua.

Ua ntej koj pib kho nrog Taltz, koj tus kws kho mob yuav kuaj xyuas seb puas muaj kab mob, xws li mob ntsws (TB), mob ntsws. Yog tias koj muaj cov tsos mob TB thaum lub sijhawm kho, nws yog qhov tseem ceeb kom hu rau koj tus kws kho mob tam sim ntawd. Cov tsos mob no suav nrog:

  • ua npaws
  • mob ib ce
  • poob phaus yam tsis tau sim
  • qhov hnoos tsis zoo uas kav ntev li 3 lub lis piam lossis ntev dua
  • hnoos tau ntshav lossis hnoos qeev
  • mob hauv siab
  • tsaus ntuj tawm hws

Zam kev kis mob thaum kho Taltz

Txhawm rau pab kom tsis txhob kis tus kab mob thaum noj Taltz, nquag ntxuav koj txhais tes. Tsis tas li, kom tsis txhob nyob ze nrog cov neeg muaj tus mob (tshwj xeeb yog hnoos, khaub thuas, lossis mob khaub thuas).

Thiab nug koj tus kws kho mob seb puas muaj tshuaj tiv thaiv uas koj yuav tsum tau txais ua ntej koj pib noj Taltz. (Saib “Taltz thiab txhaj tshuaj muaj sia” nyob hauv ntu “Taltz kev sib cuam tshuam” hauv qab no kom paub ntau ntxiv.)

Cov mob ntawm txoj hnyuv

Yog tias koj noj Taltz, nws muaj qhov pheej hmoo me me uas koj yuav pib mob plab hnyuv (IBD). IBD yog ib pawg kab mob uas ua rau mob (o) hauv koj txoj hnyuv zom zaub mov. Cov kab mob no suav nrog Crohn's disease thiab ulcerative colitis.

Yog tias koj twb muaj IBD, Taltz tuaj yeem ua rau nws tsis zoo, tab sis qhov no tsis tshua muaj tshwm sim. Hauv kev tshawb fawb soj ntsuam, Crohn tus mob tshwm sim hauv 0.1% ntawm cov neeg uas tau txais Taltz. Thiab 0.2% ntawm cov neeg uas tau txais Taltz muaj qhov mob tshiab lossis mob plab hlaub heev.

Koj yuav tsum ntsib koj tus kws kho mob yog tias koj muaj cov tsos mob tshiab lossis phem ntawm IBD. Cov no tuaj yeem suav nrog:

  • mob hauv koj lub plab (plab)
  • raws plab, nrog lossis tsis muaj ntshav
  • poob phaus

Qhov hnyav los sis ceeb thawj (tsis muaj kev cuam tshuam)

Kev hnyav nce thiab poob ceeb thawj tsis tau qhia tawm hauv kev tshawb fawb tshawb txog Taltz. Txawm li cas los xij, kev poob phaus tuaj yeem yog qhov tsos mob ntawm tuberculosis (TB) lossis mob hnyuv (IBD). Thiab cov mob no yog ob qho tib si phiv ntawm Taltz. Yog li yog tias koj poob ceeb thawj thaum noj Taltz, nws yog qhov tseem ceeb kom ntsib koj tus kws kho mob.

Yog tias koj muaj kev txhawj xeeb txog kev hnyav los yog poob phaus, tham nrog koj tus kws kho mob.

Cov plaub hau poob lawm (tsis muaj kev cuam tshuam)

Cov plaub hau tsis pom nyob hauv kev tshawb fawb ntawm Taltz. Txawm li cas los xij, plaub hau plaub hau tuaj yeem yog los ntawm cov tawv nqaij mob taub hau loj, ib hom ntawv ntawm cov quav hniav mob psoriasis tuaj yeem kho Taltz. Los ntawm khawb khawb koj cov tawv taub hau lossis khaws tawm ntawm cov nplai, koj tuaj yeem rub tawm koj cov plaub hau.

Yog tias koj muaj kev txhawj xeeb txog kev txiav plaub hau, tham nrog koj tus kws kho mob.

Kev Nyuaj Siab (tsis muaj kev cuam tshuam)

Kev nyuaj siab tsis qhia tawm tias yog kev phiv los cuam tshuam hauv kev tshawb fawb hauv Taltz. Txawm li cas los xij, kev nyuaj siab yog tshwm sim hauv cov neeg muaj psoriasis lossis psoriatic mob caj dab, uas Taltz siv los kho.

Ib txoj kev tshawb nrhiav tshuaj yuav ua li cas Taltz cuam tshuam cov tsos mob ntawm kev nyuaj siab hauv cov neeg muaj psoriasis. Cov kws tshawb nrhiav pom tias kwv yees li 40% ntawm cov neeg uas tau txais Taltz rau 12 lub lis piam rov zoo los ntawm lawv cov kev nyuaj siab tshwm sim.

Cov kab mob ntawm daim tawv nqaij xws li psoriasis tuaj yeem muaj qhov tseem ceeb ntawm kev xav ntawm lub hlwb. Yog tias koj poob siab, mob siab, lossis ntxhov siab, nco ntsoov nrog koj tus kws kho mob tham txog nws. Qee zaum tsuas tham txog koj cov kev txhawj xeeb xwb yuav pab tau. Tab sis yog tias koj tus kws kho mob xav tias koj muaj kev ntxhov siab, koj yuav tsum tau kho rau nws. Qhov no tuaj yeem tawm hauv txoj kev kho mob hlwb lossis kev siv tshuaj kho mob.

Pob txuv (tsis muaj kev cuam tshuam)

Pob txuv tsis qhia tawm yog cov kev mob tshwm sim hauv kev tshawb fawb ntawm Taltz. Txawm li cas los xij, tom qab Taltz raug pom zoo, muaj ob peb tus neeg qhia txog [KD1] [AK2] muaj pob ntxau lossis tawv nqaij ua pob. Tab sis cov xwm txheej no tsis tshua muaj, thiab nws tsis paub meej tias Taltz ua rau pob txuv.

Psoriasis tshuaj kho mob qee zaum siv los kho hom mob pob txuv, hu ua pob txuv inversa (los yog zais ntawm lub plab hliav dej). Ntawd yog vim hais tias ntxau inversa cuam tshuam nrog cov tawv nqaij mob, o, zoo li psoriasis.

Tab sis Taltz tsis tau kawm rau cov neeg uas muaj pob ntxau txhua yam. Tam sim no, tsuas yog cov tshuaj pom zoo los kho pob txuv inversa yog Humira (adalimumab).

Yog tias koj muaj kev txhawj xeeb txog mob pob txuv, tham nrog koj tus kws kho mob. Lawv tuaj yeem tawm tswv yim txoj hauv kev los kho nws.

Taltz nqi

Ib yam li txhua yam tshuaj, cov nqi ntawm Taltz tuaj yeem sib txawv. Txhawm rau nrhiav cov nqi tam sim no rau Taltz hauv koj thaj chaw, xyuas tawm WellRx.com. Tus nqi koj pom ntawm WellRx.com yog qhov koj tuaj yeem them yam tsis muaj kev pov hwm. Tus nqi tiag uas koj yuav them yog nyob ntawm koj hom is saws las, koj qhov chaw nyob, thiab lub tsev muag tshuaj koj siv.

Kev pab nyiaj thiab kev tuav pov hwm

Yog tias koj xav tau kev pabcuam nyiaj txiag los them rau Taltz, lossis yog koj xav tau kev pabcuam kom nkag siab txog koj cov nyiaj pov hwm kev tiv thaiv, muaj kev pab.

Eli Lilly thiab Tuam Txhab, cov chaw tsim khoom ntawm Taltz, muaj daim npav khaws nyiaj thiab cov kev pab txhawb nqa hu ua Taltz Together. Yog xav paub cov ntaub ntawv ntau ntxiv thiab nrhiav seb koj puas tsim nyog tau txais kev pab, hu 844-825-8966 lossis mus saib lub vev xaib website.

Taltz siv

Lub Chaw Tswj Xyuas Khoom Noj thiab Tshuaj (FDA) tau pom zoo kev siv tshuaj xws li Taltz los kho qee yam mob. Taltz kuj tseem siv tau daim ntawv lo-off rau lwm yam mob. Kev siv tshuaj tua (label-label) yog thaum siv tshuaj uas raug pom zoo los kho ib yam mob yog siv los kho tus mob txawv.

Taltz rau mob caj dab psoriatic

Taltz yog FDA pom zoo kom kho kho mob psoriatic mob caj dab hauv cov neeg laus.

Psoriatic mob caj dab yog ib hom kev mob caj dab hauv qhov twg ib los ntau ntau cov qij ntshav o tuaj, o, thiab txhav. Tus mob tshwm sim li ntawm 30% ntawm cov neeg muaj tus mob psoriasis. Nws kuj tseem muaj peev xwm los tsim kev mob taub hau ua ntej koj muaj psoriasis ntawm koj cov tawv nqaij.

Psoriatic mob caj dab feem ntau cuam tshuam cov pob qij txha hauv koj:

  • ntiv tes
  • ntiv taw
  • hauv caug
  • qij taws
  • dab teg
  • qis dua rov qab

Taltz txo qhov mob (o) thiab mob hauv koj cov pob qij txha. Cov tshuaj kuj tseem yuav ua kom yooj yim rau koj kom txav mus thiab ua haujlwm txhua hnub, xws li kev hnav khaub ncaws, ntxhua khaub ncaws, noj mov thiab taug kev.

Ua tau zoo rau kev mob caj dab

Cov kev tshawb fawb soj ntsuam saib yuav ua li cas Taltz cuam tshuam cov tsos mob ntawm kev mob caj dab. Cov kws tshawb nrhiav tau sau tseg tias tib neeg muaj mob npaum li cas thiab lawv ua tiav txhua hnub. Cov kws tshawb nrhiav kuj txiav txim seb muaj pes tsawg tus neeg lub pob qij txha tau hloov pauv lossis o tuaj.

Tom qab 24 lub lis piam, Taltz txhim kho cov tsos mob no los ntawm:

  • tsawg kawg 20% ​​hauv 53% rau 58% ntawm cov neeg
  • tsawg kawg 50% hauv 35% txog 40% ntawm cov neeg
  • tsawg kawg 70% hauv 22% rau 23% ntawm cov neeg

Taltz rau kev muaj mob hnyav rau cov quav hniav mob psoriasis

Taltz yog FDA pom zoo kom kho kab mob psoriasis mob taub hau thiab mob hnyav rau cov neeg laus thiab menyuam hnub nyoog 6 xyoo thiab laus dua. Nws haum rau cov neeg muaj mob psoriasis tuaj yeem tau txais txiaj ntsig los ntawm kev kho mob system (kev kho uas cuam tshuam rau koj lub cev tag nrho) lossis kev kho duab ci (kev kho mob me me).

Cov quav hniav psoriasis feem ntau muaj tus mob psoriasis. Nws tuaj yeem yog los ntawm mob sib khuav mus rau mob hnyav. Koj tus kws kho mob tuaj yeem qhia koj tias mob psoriasis hnyav npaum li cas thiab seb Taltz puas zoo rau koj. Koj qhov psoriasis tuaj yeem tsim nyog rau kev kho mob nrog Taltz yog tias:

  • koj muaj cov quav hniav (tuab, xim liab, pob zeb tawv ntoo) ntau dua 3% ntawm koj lub cev
  • koj muaj cov ntaub qhwv ntsej muag ntawm koj txhais tes, ko taw, lossis ntawm chaw mos
  • koj lub psoriasis zoo heev cuam tshuam rau koj lub neej zoo
  • Cov kev kho mob uas yog tshuaj pleev (thov rau koj cov tawv nqaij) tsis tau coj koj lub ntsej muag psoriasis

Taltz pab txo kom tsawg tus mob psoriasis plaques thiab mob heev npaum li cas.

Cov hauj lwm zoo rau cov quav hniav psoriasis rau cov neeg laus

Cov kev tshawb fawb soj ntsuam tau saib yuav ua li cas Taltz cuam tshuam cov tsos mob ntawm cov quav hniav psoriasis rau cov neeg laus hnub nyoog 18 xyoo thiab laus dua. Tom qab 12 lub lis piam, Taltz relieved cov tsos mob los ntawm:

  • tsawg kawg 75% hauv 87% txog 90% ntawm cov neeg
  • tsawg kawg 90% hauv 68% rau 71% ntawm tib neeg
  • 100% hauv 35% rau 40% neeg

Cov kws tshawb nrhiav kuj tau saib seb Taltz ua haujlwm tau zoo npaum li cas rau cov neeg uas muaj cov tsos mob ntawm tus mob psoriasis tau ploj mus, lossis tsuas muaj hnub nyoog qis dua, tom qab 12 lub lis piam ntawm kev kho mob. Tom qab 60 lub lim piam ntawm kev noj Taltz, 75% ntawm cov neeg no tseem muaj tsawg los yog tsis muaj cov tsos mob psoriasis.

Thiab hauv kev tshawb fawb txog kev kho mob ntawm chaw ua paug ntawm caj ces, 73% ntawm cov neeg uas tau txais Taltz tsuas yog cov kev mob me lossis tau muaj cov tsos mob kom meej meej tom qab 12 lub lis piam.

Kev ntxim rau cov quav hniav psoriasis rau cov menyuam yaus

Cov kev tshawb fawb soj ntsuam xyuas saib yuav ua li cas Taltz cuam tshuam cov tsos mob ntawm cov quav hniav mob psoriasis rau cov menyuam yaus hnub nyoog 6 txog 18 xyoo. Tom qab 12 lub lis piam, Taltz relieved cov tsos mob los ntawm:

  • tsawg kawg 75% hauv 89% ntawm cov menyuam
  • tsawg kawg 90% hauv 78% ntawm cov menyuam
  • 100% hauv 50% ntawm cov menyuam yaus

Taltz rau spondyloarthritis

Taltz yog FDA pom zoo los kho ob hom mob spondyloarthritis (SA) hauv cov laus. Tshwj xeeb, Taltz raug pom zoo kom kho ob daim ntawv hauv qab no ntawm SA, uas tau piav qhia ntau yam hauv qab no:

  • non-radiographic axial spondyloarthritis (nr-axSpA)
  • nquag ankylosing spondylitis (AS) lossis radiographic axial spondyloarthritis (r-axSpA)

SA yog ib qho mob tshwm sim thiab ib daim ntawv mob caj dab uas ua rau o ntawm koj nqaj qaum. Feem ntau, cov pob qij txha nyob ze kuj raug cuam tshuam, tshwj xeeb ob lub pob qij txha uas txuas koj caj qaum qis rau koj lub plab (pob qij txha sacropelvic). Thaum kev puas tsuaj rau cov pob qij txha tsis pom tshwm ntawm xoo duab hluav taws xob (xoo hluav taws xob), daim qauv ntawm SA yog hu ua nr-axSpA.

Thaum SA loj zuj zus, qhov mob ntev ntev (mob ntev ntev) tuaj yeem ua rau txha caj qaum ntawm koj tus txha nraub qaum mus fuse ua ke. Raws li qhov tshwm sim, koj lub nqaj qaum yuav tsis hloov tau. Mob nraub qaum thiab nkees yog cov tsos mob tshwm sim ntawm SA uas tau nce zuj zus tuaj. Nrog rau hom SA no, kev sib koom tes sib puas tuaj yeem pom ntawm xoo hluav taws xob. Daim foos ntawm SA no yog hu ua active AS, lossis r-axSpA.

Kev ua tau zoo rau qhov tsis-radiographic axial spondyloarthritis

Kev soj ntsuam kawm tau saib rau cov neeg laus hnub nyoog 18 xyoo thiab laus dua nrog nr-axSpA. Qhov kev tshawb nrhiav no tau saib txog kev kho mob nrog Taltz piv nrog cov tshuaj uas muaj placebo (kho tsis muaj tshuaj nyob hauv).

Tom qab 52 lub lim tiam ntawm kev kho mob:

  • 30% ntawm cov neeg siv Taltz muaj lawv cov tsos mob txo los ntawm 40% lossis ntau dua. Cov tsos mob no suav nrog txhav hauv lawv cov pob qij txha thiab txha nraub qaum.
  • Hauv kev sib piv, 13% ntawm cov tib neeg siv cov placebo muaj tib lub txiaj ntsig.

Ua tau hauj lwm zoo rau ankylosing spondylitis

Ob qhov kev tshawb fawb soj ntsuam tau saib rau cov laus muaj hnub nyoog 18 xyoo lossis tshaj saud nrog active AS. Cov kev tshawb fawb no tau saib xyuas kev kho mob nrog Taltz piv nrog kev ntawm cov placebo.

Tom qab 16 lub lim tiam ntawm kev kho mob:

  • 25% rau 48% ntawm cov neeg siv Taltz muaj lawv cov tsos mob txo los ntawm 40% lossis ntau dua. Cov tsos mob no suav nrog txhav hauv lawv cov pob qij txha thiab txha nraub qaum.
  • Hauv kev sib piv, 13% mus rau 18% ntawm cov tib neeg siv cov placebo muaj tib lub txiaj ntsig.

Ntxiv rau, cov neeg uas siv Taltz muaj mob tsawg dua thiab ua rau lub cev zoo dua piv nrog cov neeg uas tau noj cov placebo.

Taltz thiab menyuam yaus

Taltz yog FDA pom zoo kho kab mob psoriasis rau cov menyuam yaus hnub nyoog 6 xyoo thiab laus dua. Yog xav paub cov ntaub ntawv hais txog kev siv no, saib rau nqe lus sau hu ua “Taltz rau kev muaj mob viav vias txaus rau hnyav.”

Taltz rau lwm yam mob

Ntxiv nrog rau kev siv teev saum toj no, Taltz kuj yuav siv cov ntawv cim npe rau lwm lub hom phiaj. Daim ntawv tshuaj siv uas tsis yog daim ntawv lo yog thaum tshuaj uas tau pom zoo rau kev siv yog siv rau ib qho txawv uas tsis tau tso cai. Thiab koj tuaj yeem xav paub yog Taltz siv rau lwm yam mob.

Taltz rau mob rheumatoid mob caj dab (siv daim ntawv lo)

Taltz tsis pom zoo kho kev mob caj dab (RA). Txawm li cas los xij, koj tus kws kho mob tuaj yeem sau tshuaj tawm sab nraud yog tias lwm txoj kev kho mob tsis tau ua haujlwm rau koj.

RA yog ib yam kabmob uas ua rau koj lub cev tiv thaiv koj cov pob qij txha, ua rau lawv o tuaj, txhav thiab mob. Ntau cov kev tshawb fawb tau saib seb Taltz tuaj yeem pab kho tus mob RA. Taltz ua haujlwm rau qee qhov kev tiv thaiv kabmob hauv lub cev tiv thaiv kab mob uas paub tias ua rau qee qhov sib koom ua ke (o).

Kev tshuaj xyuas cov kev tshawb fawb xaus lus tias Taltz tau txais txiaj ntsig los kho RA.

Yog tias koj xav paub ntau ntxiv txog kev siv Taltz los kho RA, tham nrog koj tus kws kho mob.

Taltz rau txha nqaj qaum (tsis yog siv tsim nyog)

Taltz tsis tau txais kev pom zoo lossis siv cov ntawv cim npe rau kev kho mob ua pob txha caj dab. Daim ntawv ntawm mob caj dab yog tshwm sim los ntawm kev coj thiab tsim kua muag ntawm koj cov pob qij txha. Nws tsis yog tshwm sim los ntawm kev o. Yog li osteoarthritis yuav tsis pab los ntawm cov tshuaj, xws li Taltz, uas cuam tshuam rau koj lub cev tsis muaj zog.

Yog tias koj muaj lus nug txog kev kho mob ua pob txha caj dab, tham nrog koj tus kws kho mob.

Taltz thiab haus dej cawv

Cawv tsis cuam tshuam ncaj qha rau Taltz ua haujlwm, yog li tsis muaj lus ceeb toom tshwj xeeb txog kev zam kev haus cawv thaum kho Taltz.

Txawm li cas los xij, haus cawv ntau yuav ua rau mob psoriasis, uas Taltz siv los kho.Ib qho ntxiv, haus dej cawv tuaj yeem ua rau kev kho mob psoriasis ua tsis tau zoo thiab tseem yuav ua rau koj lub cev tiv thaiv kab mob tsis muaj zog tuaj yeem tua kab mob.

Cov lus qhia tam sim no txog kev kho thiab tswj cov mob psoriasis pom zoo kom koj tsuas haus cawv ntau npaum li cas.

Yog tias koj haus cawv, nug koj tus kws kho mob seb koj yuav haus ntau npaum li cas thaum noj Taltz.

Lwm txoj cai los ntawm Taltz

Muaj lwm yam tshuaj uas tuaj yeem kho koj tus mob. Qee tus kuj yuav zoo dua rau koj dua li lwm tus. Yog tias koj xav paub txog lwm txoj hauv kev rau Taltz, tham nrog koj tus kws kho mob. Lawv tuaj yeem qhia koj txog lwm cov tshuaj uas yuav ua haujlwm zoo rau koj.

Nco tseg: Qee cov tshuaj teev rau ntawm no tau siv daim ntawv lo npe coj los kho cov mob no.

Xaiv lwm cov kev mob caj dab

Piv txwv ntawm lwm yam tshuaj uas tuaj yeem siv los kho tus mob psoriatic muaj xws li:

  • methotrexate (Otrexup, Rasuvo, Trexall)
  • tshuaj tua kab (Otezla)
  • infliximab (Nco)
  • adalimumab (Humira)
  • etanercept (Enbrel)
  • tofacitinib (Xeljanz)
  • golimumab (Simponi)
  • certolizumab (Cimzia)
  • secukinumab (Cosentyx)
  • ustekinumab (Stelara)
  • brodalumab (Siliq)
  • guselkumab (Tremfya)
  • sulfasalazine (Azulfidine)

Nco tseg: Yog xav paub ntxiv txog kev mob caj dab, saib ntu “Taltz siv” ntu saud.

Hloov chaw rau mob qaij mus rau mob hnyav rau cov quav hniav psoriasis

Piv txwv ntawm lwm yam tshuaj uas tej zaum yuav siv los kho mob sib khuav xws li mob quav hniav xws li:

  • tshuaj tua kab (Otezla)
  • infliximab (Nco)
  • adalimumab (Humira)
  • etanercept (Enbrel)
  • certolizumab (Cimzia)
  • ustekinumab (Stelara)
  • secukinumab (Cosentyx)
  • brodalumab (Siliq)
  • guselkumab (Tremfya)
  • golimumab (Simponi)
  • methotrexate (Otrexup, Rasuvo, Trexall)
  • sulfasalazine (Azulfidine)

Nco tseg: Yog xav paub ntau ntxiv txog cov quav hniav psoriasis, saib hauv seem “Taltz siv” ntu saud.

Hloov chaw rau ankylosing spondylitis

Piv txwv ntawm lwm cov tshuaj uas tuaj yeem siv los kho ankylosing spondylitis (AS) suav nrog:

  • infliximab (Nco)
  • adalimumab (Humira)
  • etanercept (Enbrel)
  • secukinumab (Cosentyx)
  • certolizumab (Cimzia)
  • golimumab (Simponi)
  • ustekinumab (Stelara)
  • brodalumab (Siliq)
  • methotrexate (Otrexup, Rasuvo, Trexall)
  • sulfasalazine (Azulfidine)

Nco tseg: Xav paub ntau ntxiv txog AS, saib hauv ntu “Taltz siv” ntu saum toj no.

Xaiv rau cov tsis muaj radiographic axial spondyloarthritis

Piv txwv ntawm lwm cov tshuaj uas tuaj yeem siv los kho cov tsis muaj radiographic axial spondyloarthritis (nr-axSpA) suav nrog:

  • certolizumab (Cimzia)
  • adalimumab (Humira)
  • secukinumab (Cosentyx)
  • methotrexate (Otrexup, Rasuvo, Trexall)
  • sulfasalazine (Azulfidine)

Nco tseg: Yog xav paub ntau ntxiv txog nr-axSpA, saib tshooj “Taltz siv” ntu saum toj no.

Taltz vs. Cosentyx

Tej zaum koj yuav xav paub seb Taltz piv rau lwm cov tshuaj uas tau sau tseg rau kev siv zoo sib xws. Ntawm no peb saib seb Taltz thiab Cosentyx zoo li cas thiab txawv.

Txog

Taltz thiab Cosentyx yog ob qho tshuaj lom tsiaj txhu tshuaj (tshuaj ua los ntawm cov chaw muaj sia). Lawv ua haujlwm los ntawm hom phiaj ib feem ntawm koj lub cev.

Taltz muaj cov tshuaj ixekizumab, thaum Cosentyx muaj cov tshuaj secukinumab. Cov tshuaj ob qho no yog ob qho hu ua cov tshuaj tiv thaiv monoclonal. Lawv thaiv cov kev ua ntawm cov protein nyob hauv koj lub cev tiv thaiv kab mob hu ua interleukin-17. Interleukin-17 ua rau koj muaj zog tiv thaiv kab mob mus tua cov hlwb hauv koj cov tawv nqaij thiab pob qij txha. Qhov no ua rau muaj qhov mob uas pom nrog cov kab mob xws li quav hniav mob psoriasis, mob caj pas psoriatic, thiab mob spondyloarthritis.

Kev Siv

Lub chaw tswj hwm khoom noj thiab Tshuaj (FDA) tau pom zoo rau Taltz thiab Cosentyx kom kho cov mob psoriasis mob ntshav tsawv mus txog rau mob hnyav. Cov tshuaj no haum rau cov neeg uas muaj kev mob psoriasis tuaj yeem tau txais txiaj ntsig los ntawm kev kho mob system (kev kho mob uas cuam tshuam rau koj lub cev tag nrho) lossis kev kho kab mob (kev kho mob lub teeb).

Rau cov quav hniav mob psoriasis, Taltz tau pom zoo siv rau cov laus thiab menyuam hnub nyoog 6 xyoo thiab tshaj saud. Txawm li cas los xij, Cosentyx tsuas yog tso cai siv rau cov neeg laus uas muaj tus mob no.

Taltz thiab Cosentyx puav leej tseem tau pom zoo los ntawm FDA los mus kho tus mob psoriatic mob caj dab hauv cov laus. ("Nquag" txhais tau tias koj tam sim no muaj cov tsos mob.)

Tsis tas li ntawd, ob qho tib si Taltz thiab Cosentyx raug pom zoo rau kev kho mob uas tsis yog radiographic axial spondyloarthritis thiab nquag ankylosing spondylitis hauv cov neeg laus.

Nco tseg: Xav paub ntau ntxiv txog cov xwm txheej hais txog ntawm no, saib sab lus “Taltz siv” ntu saud.

Cov ntaub ntawv tshuaj thiab kev tswj hwm

Ob qho Taltz thiab Cosentyx raug muab los ntawm kev txhaj tshuaj hauv qab koj cov tawv nqaij (txhaj tshuaj subcutaneous). Koj tus kws kho mob yuav muab kev txhaj tshuaj rau koj thaum xub thawj. Tom qab ntawd lawv tuaj yeem qhia koj yuav ua li cas txhaj tshuaj rau koj tus kheej tom tsev.

Taltz los ua ob hom: ib leeg-siv prefilled koob txhaj tshuaj thiab ib-siv prefilled autoinjector cwj mem.

Cosentyx los hauv peb hom:

  • ib-siv Sensoready cwj mem
  • ib leeg-siv koob txhaj tshuaj prefilled
  • ib qho vial uas tau muab los ua kev txhaj tshuaj los ntawm koj tus kws kho mob

Phiv thiab txaus ntshai

Taltz thiab Cosentyx tuaj yeem ua rau muaj kev phiv zoo sib xws thiab qee qhov sib txawv. Hauv qab no yog cov piv txwv ntawm cov kev mob tshwm sim no.

Ntau cov kev mob tshwm sim

Cov npe no muaj cov piv txwv ntawm cov kev mob tshwm sim ntau uas tuaj yeem tshwm sim nrog Taltz, nrog Cosentyx, lossis nrog ob qho tshuaj (thaum noj ib leeg).

  • Yuav tshwm sim nrog Taltz:
    • Qhov chaw txhaj tshuaj lom (liab thiab mob ncig thaj chaw txhaj tshuaj)
    • mob muag (liab muag)
  • Yuav tshwm sim nrog Cosentyx:
    • zawv plab
    • qhov ncauj tawm
    • daim tawv nqaij ua pob
  • Yuav tshwm sim nrog ob Taltz thiab Cosentyx:
    • mob ua npaws, yam li ncaws pob ko taw
    • cov kab mob sab sauv, xws li mob khaub thuas
    • xeev siab

Cov kev mob tshwm sim hnyav heev

Cov npe no muaj cov piv txwv ntawm cov kev mob tshwm sim loj heev uas tuaj yeem tshwm sim nrog ob qho Taltz thiab Cosentyx (thaum noj ib leeg zuj zus).

  • nce kev pheej hmoo ntawm tus kab mob uas tej zaum yuav loj, xws li mob ntsws (TB)
  • mob rau cov hnyuv lossis cov mob ua paug (IBD), xws li Crohn's mob lossis mob ua mob rau daim siab
  • kev fab tshuaj hnyav heev

Txij nkawm

Taltz thiab Cosentyx nyias muaj nyias kev siv pom zoo los ntawm FDA, tab sis nkawd ob leeg tau siv los kho cov mob hauv qab no:

  • mob pes nrab mus rau qhov mob heev ntawm cov quav hniav psoriasis
  • mob caj dab mob uas nquag (tam sim no ua rau cov tsos mob)
  • tsis-radiographic axial spondyloarthritis
  • nquag ankylosing spondylitis

Cov tshuaj no tsis tau muab piv rau hauv cov kev tshawb fawb. Txawm li cas los xij, ib qho kev tshuaj xyuas ntawm kev tshawb xyuas ntawm cov quav hniav psoriasis pom tias Taltz pab tau zoo dua li Cosentyx ntawm kev txo cov tsos mob ntawm tus mob psoriasis.

Cov txheej txheem kev kho mob txij li xyoo 2018 thiab 2019 pom zoo ob qho tshuaj yog kev xaiv rau cov tib neeg uas xav tau kev kho mob rau kab mob psoriasis lossis mob caj dab. Kev kho mob xyoob ntoo yog ib hom tshuaj uas tsom rau feem ntawm koj lub cev tiv thaiv kab mob uas tau koom nrog psoriasis thiab mob caj dab.

Koj tus kws kho mob yuav pom zoo siv tshuaj lom yog tias lwm yam kev kho mob tsis ua haujlwm txaus. Piv txwv li, ib txoj kev siv tsiaj txhu rau koj yog hais tias:

  • koj muaj cov kab mob psoriasis thiab kho cov teeb ci lossis kev kho mob uas siv rau koj cov tawv nqaij tsis tau ua haujlwm
  • koj muaj psoriatic mob caj dab thiab kev kho mob tiv thaiv (uas pab txo kev o) xws li cov tshuaj kho mob lossis tshuaj steroids tsis tau ua haujlwm

Cosentyx yuav zoo dua Taltz rau cov quav hniav mob psoriasis uas cuam tshuam cov rau tes. Taltz tuaj yeem yog qhov kev xaiv zoo dua rau erythrodermic psoriasis, muaj feem ntau tsis tshua muaj mob psoriasis.

Cov nqi

Taltz thiab Cosentyx yog ob hom tshuaj muaj npe. Tam sim no tsis muaj cov ntaub ntawv tsis tseem ceeb ntawm ib yam yeeb tshuaj. Cov tshuaj muaj npe lag luam feem ntau raug nqi ntau dua li cov generics.

Raws li kev kwv yees nyob rau WellRx.com, Taltz thiab Cosentyx feem ntau raug nqi ib yam. Tus nqi tiag uas koj yuav them rau ib qho tshuaj yog nyob ntawm koj qhov kev tuav pov hwm, koj qhov chaw nyob, thiab lub tsev muag tshuaj uas koj siv.

Taltz thiab Humira

Ntxiv nrog rau Cosentyx (saum toj), Humira yog lwm qhov tshuaj uas muaj qee qhov siv zoo ib yam li cov tshuaj Taltz. Ntawm no peb saib seb Taltz thiab Humira zoo ib yam thiab txawv.

Txog

Taltz thiab Humira yog ob qho tshuaj lom tsiaj txhu tshuaj (tshuaj ua los ntawm cov chaw muaj sia). Lawv ib leeg ua haujlwm los ntawm hom phiaj sib txawv, tab sis tshwj xeeb, ntu ntawm koj lub cev.

Taltz muaj ixekizumab, uas yog hom tshuaj hu ua monoclonal antibody. Nws txwv cov kev ua ntawm cov protein nyob hauv lub cev tiv thaiv kab mob hu ua interleukin-17. Interleukin-17 ua rau lub cev tiv thaiv kabmob ua rau cov kabmob ntawm daim tawv nqaij thiab pob qij txha. Qhov no ua rau muaj qhov mob uas pom nrog cov kab mob xws li quav hniav psoriasis, mob caj pas psoriatic, thiab spondyloarthritis.

Humira muaj adalimumab, uas yog ib hom tshuaj hu ua qog necrosis factor-alpha (TNF-α) blocker. Nws thaiv cov kev ua ntawm cov protein hu ua TNF-α. Cov protein no koom nrog ua rau mob hauv ntau yam mob, suav nrog psoriasis thiab mob caj dab.

Kev Siv

Lub Chaw Tswj Xyuas Khoom Noj thiab Tshuaj (FDA) tau pom zoo rau ob qho tib si Taltz thiab Humira los kho kho tus mob plaque psoriasis muaj mob pes nrab mus rau mob hnyav. Koj tus kws kho mob yuav sau ntawv rau ib qho ntawm cov tshuaj no yog tias koj psoriasis tuaj yeem tau txais txiaj ntsig los ntawm kev kho mob system (kev kho uas cuam tshuam rau koj lub cev tag nrho) lossis phototherapy (kev kho mob me me).

Rau cov quav hniav mob psoriasis, Taltz tau pom zoo siv rau cov laus thiab menyuam hnub nyoog 6 xyoo thiab tshaj saud. Txawm li cas los xij, Humira tsuas yog pom zoo siv rau cov neeg laus uas muaj tus mob no.

Taltz thiab Humira kuj tseem tau pom zoo FDA los kho tus mob psoriatic mob caj dab hauv cov neeg laus. ("Nquag" txhais tau tias koj tam sim no muaj cov tsos mob.)

Ib qho ntxiv, ob leeg Taltz thiab Humira raug pom zoo rau kev kho mob nquag ankylosing spondylitis rau cov neeg laus. Tab sis tsuas yog Taltz raug pom zoo rau kev kho mob uas tsis yog-radiographic axial spondyloarthritis ntawm cov neeg laus.

Humira tseem tau ntawv pom zoo los ntawm FDA rau kev kho mob raws li nram no:

  • rheumatoid mob caj dab (RA)
  • cov me nyuam mus txog rau mob qog caj dab idiopathic mob caj dab
  • Crohn tus kab mob
  • mob pes nrab mus rau mob siab txog mob plab
  • hidradenitis suppurativa, mob tawv nqaij mob tseem hu ua pob txuv inversa
  • qee yam mob uas tsis kis rau qhov mob (ib hom mob ntawm qhov muag), suav nrog uveitis ntu nruab nrab, mob txha nqaj qaum, thiab mob rau daim tawv nqaij.

Nco tseg: Xav paub ntau ntxiv txog tus mob Taltz raug pom zoo kho, saib ntu “Taltz siv” ntu saud.

Cov ntaub ntawv tshuaj thiab kev tswj hwm

Taltz thiab Humira ob leeg tau muab los ntawm kev txhaj tshuaj hauv qab koj cov tawv nqaij (txhaj tshuaj subcutaneous). Koj tus kws kho mob yuav muab kev txhaj tshuaj rau koj thaum xub thawj. Tom qab ntawd lawv tuaj yeem qhia koj yuav ua li cas txhaj tshuaj rau koj tus kheej tom tsev.

Taltz los ua ob hom: ib leeg-siv prefilled koob txhaj tshuaj thiab ib-siv prefilled autoinjector cwj mem.

Humira los txog peb hom:

  • ib-siv cwj mem uas muab los ua tus sau
  • ib leeg-siv koob txhaj tshuaj prefilled
  • ib qho vial uas tau muab los ua kev txhaj tshuaj los ntawm koj tus kws kho mob

Phiv thiab txaus ntshai

Taltz thiab Humira tuaj yeem ua rau muaj kev phiv zoo sib xws thiab qee qhov sib txawv. Hauv qab no yog cov piv txwv ntawm cov kev mob tshwm sim no.

Ntau cov kev mob tshwm sim

Cov npe no muaj cov piv txwv ntawm cov kev mob tshwm sim ntau uas tuaj yeem tshwm sim nrog Taltz, nrog Humira, lossis nrog ob qho tshuaj (thaum noj ib leeg).

  • Yuav tshwm sim nrog Taltz:
    • tinea kab mob fungal, xws li mob kis las
    • mob muag (liab muag)
  • Yuav tshwm sim nrog Humira:
    • mob taub hau
    • ua pob
  • Yuav tshwm sim nrog ob Taltz thiab Humira:
    • Qhov chaw txhaj tshuaj tiv thaiv, xws li liab thiab mob ncig thaj chaw txhaj tshuaj
    • cov kab mob sab sauv, xws li mob khaub thuas
    • xeev siab

Cov kev mob tshwm sim hnyav heev

Cov npe no muaj cov piv txwv ntawm cov kev mob tshwm sim loj uas tuaj yeem tshwm sim nrog Taltz, nrog Humira, lossis nrog ob qho tshuaj (thaum noj ib leeg).

  • Yuav tshwm sim nrog Taltz:
    • mob rau cov hnyuv lossis cov mob ua paug (IBD), xws li Crohn's mob lossis mob ua mob rau daim siab
  • Yuav tshwm sim nrog Humira:
    • mob siab, xws li daim siab ua haujlwm
    • cov teeb meem ntawm cov hlab hlwb, xws li ntau tus sclerosis (MS)
    • cov teeb meem ntshav, xws li txo cov qe ntshav liab, qe ntshav dawb, lossis qe ntshav
    • lub plawv tsis ua hauj lwm
    • mob fungal, xws li histoplasmosis
    • nce kev pheej hmoo ntawm qee cov qog nqaij hlav, xws li mob qog nqaij daim tawv, mob qog ntshav, thiab mob qog nqaij hlav
    • psoriasis tshiab lossis ntog tsis zoo
  • Yuav tshwm sim nrog ob Taltz thiab Humira:
    • nce kev pheej hmoo ntawm tus kab mob uas tej zaum yuav loj, xws li mob ntsws (TB)
    • kev fab tshuaj hnyav heev

Txij nkawm

Taltz thiab Humira muaj kev siv FDA pom zoo sib txawv, tab sis nkawd ob leeg tau siv los kho cov mob hauv qab no:

  • mob pes nrab mus rau qhov mob heev ntawm cov quav hniav psoriasis
  • nquag psoriatic mob caj dab
  • nquag ankylosing spondylitis

Cov tshuaj no tsis tau muab piv rau cov tib neeg muaj kab mob voos, tab sis kev tshawb fawb pom tias Taltz thiab Humira muaj txiaj ntsig zoo los kho tus mob no.

Ib qhov kev tshawb fawb soj ntsuam saib ob qho tib si Taltz thiab Humira hauv cov neeg muaj kev mob caj dab. Tom qab 24 lub asthiv, cov tsos mob ntawm tus mob psoriatic mob tsawg los ntawm tsawg kawg 20% ​​hauv 58% rau 62% ntawm cov neeg uas tau siv Taltz. Qhov no piv rau 57% ntawm cov neeg uas coj Humira thiab 30% uas noj tshuaj placebo (tsis kho).

Cov txheej txheem kho mob txij li xyoo 2018 thiab 2019 pom zoo ob qho tshuaj yog kev xaiv rau cov tib neeg uas xav tau kev kho mob biologic rau mob psoriasis lossis mob pob qij txha. Kev kho mob xyoob ntoo yog ib hom tshuaj uas tsom rau feem ntawm koj lub cev tiv thaiv kab mob uas tau koom nrog psoriasis thiab mob caj dab.

Koj tus kws kho mob yuav pom zoo siv tshuaj lom yog tias lwm yam kev kho mob tsis ua haujlwm txaus. Piv txwv li, ib txoj kev siv tsiaj txhu rau koj yog hais tias:

  • koj muaj cov kab mob psoriasis thiab kho cov teeb ci lossis kev kho mob uas siv rau koj cov tawv nqaij tsis tau ua haujlwm
  • koj muaj psoriatic mob caj dab thiab kev kho mob tiv thaiv (uas pab txo kev o) xws li cov tshuaj kho mob lossis tshuaj steroids tsis tau ua haujlwm

Rau cov tib neeg feem coob uas pib kho mob rau kev mob caj dab, muaj kev coj ua 2018 pom zoo kom siv TNF-alpha blockers (xws li Humira) tshaj interleukin-17 blockers (xws li Taltz). Cov txheej txheem 2019 hais tias Humira kuj tseem yuav zoo dua Taltz rau cov quav hniav mob psoriasis uas cuam tshuam rau saum tawv taub hau thiab rau erythrodermic psoriasis (hom mob psoriasis tsawg).

Cov kev tshawb fawb soj ntsuam piv rau cov neeg muaj txiaj ntsig Taltz thiab Humira muaj kev kho kev mob caj dab thiab plaque psoriasis. Txoj kev tshawb no tau tshaj tawm tias dhau 24 lub lim tiam ntawm kev kho mob, 36% ntawm cov neeg uas tau siv tshuaj Taltz muaj lawv cov kev mob tshwm sim los tsawg kawg 50%. Hauv kev sib piv, 28% ntawm cov neeg uas coj Humira muaj lawv cov kev mob tshwm sim los tsawg kawg 50%.

Cov nqi

Taltz thiab Humira yog ob qho tshuaj uas nrov npe. Tam sim no tsis muaj cov ntaub ntawv tsis tseem ceeb ntawm ib yam yeeb tshuaj. Cov tshuaj muaj npe lag luam feem ntau raug nqi ntau dua li cov generics.

Raws li kev kwv yees nyob rau WellRx.com, Taltz thiab Humira feem ntau raug nqi ib yam nkaus. Tus nqi tiag uas koj yuav them rau ib qho tshuaj yog nyob ntawm koj qhov kev tuav pov hwm, koj qhov chaw nyob, thiab lub tsev muag tshuaj uas koj siv.

Taltz kev sib cuam tshuam

Taltz tuaj yeem cuam tshuam nrog qee yam tshuaj ntxiv. Kev sib cuam tshuam sib txawv tuaj yeem ua rau txawv txav. Piv txwv li, qee qhov kev cuam tshuam tuaj yeem cuam tshuam nrog txoj kev siv tshuaj zoo li cas. Lwm cov kev sib cuam tshuam muaj peev xwm nce cov kev phiv los sis ua rau nws hnyav dua.

Taltz thiab lwm yam tshuaj noj

Hauv qab no yog cov npe tshuaj uas tuaj yeem cuam tshuam nrog Taltz. Daim ntawv no tsis muaj tag nrho cov tshuaj uas yuav cuam tshuam nrog Taltz.

Ua ntej noj Taltz, tham nrog koj tus kws kho mob thiab kws muag tshuaj. Qhia rau lawv txog txhua yam tshuaj noj, tsis-kiab khw, thiab lwm yam tshuaj koj noj. Kuj tseem qhia rau lawv txog cov vitamins, tshuaj ntsuab, thiab tshuaj siv uas koj siv. Sib qhia cov ntaub ntawv no tuaj yeem pab koj kom tsis txhob muaj kev cuam tshuam.

Yog tias koj muaj lus nug txog kev sib txuam nrog tshuaj uas yuav cuam tshuam koj, nug koj tus kws kho mob lossis kws muag tshuaj.

Taltz thiab warfarin

Warfarin (Coumadin, Jantoven) yog ib hom tshuaj ntshav ntshav, yog cov tshuaj uas pab tiv thaiv cov ntshav txhaws. Kev noj Taltz nrog warfarin yuav ua rau koj cov tshuaj warfarin tsis muaj kev tiv thaiv zoo.

Yog tias koj noj tshuaj warfarin, koj tus kws kho mob yuav xav saib nws yuav ntev npaum li cas rau koj cov ntshav txhaws tom qab koj pib Taltz, lub sijhawm kho koj tus mob, thiab yog tias koj txiav Taltz. Lawv tuaj yeem hloov kho koj kev noj tshuaj warfarin yog xav tau.

Taltz thiab cyclosporine

Cyclosporine yog ib qho tshuaj tiv thaiv tshuaj tiv thaiv kab mob. Koj coj nws mus txo qhov haujlwm ntawm koj lub cev tsis muaj zog. Noj Taltz nrog cyclosporine yuav ua rau koj cyclosporine tsis muaj kev tiv thaiv zoo.

Yog tias koj noj tshuaj cyclosporine, koj tus kws kho mob yuav xav soj ntsuam cov tshuaj hauv koj cov ntshav tom qab koj pib Taltz, thaum kho koj tus mob thiab yog tias koj txiav Taltz. Lawv tuaj yeem hloov kho koj li tshuaj cyclosporine yog xav tau.

Cyclosporine tseem tseem muaj cov tshuaj uas muaj npe zoo li nram no:

  • Cequa
  • Gengraf
  • Neoral
  • Txhab Nyiaj
  • Sandimmune

Taltz thiab txhaj tshuaj muaj sia nyob

Mus txhaj tshuaj tiv thaiv thaum koj tseem tab tom noj Taltz tuaj yeem ua rau kis mob hnyav tau.

Cov tshuaj tiv thaiv muaj sia muaj cov kab mob uas tsis muaj zog tiv thaiv kab mob los yog kab mob, tab sis lawv tsis ua rau cov neeg muaj zog tiv thaiv kab mob tsis muaj mob. Txawm li cas los xij, cov tshuaj tiv thaiv muaj sia nyob tuaj yeem ua rau kis kab mob hauv cov neeg tiv thaiv kab mob uas cuam tshuam los ntawm kev kho mob nrog Taltz.

Thaum koj tseem tab tom noj Taltz, koj yuav tsum tsis txhob txhaj tshuaj tiv thaiv xws li:

  • qhua pias
  • ua npaws daj
  • tuberculosis (TB)
  • qhua pias qoob, mob qog, thiab rubella (MMR)

Nws zoo yog tias koj mus txhaj tshuaj tiv thaiv (tsis muaj sia nyob), xws li kev txhaj tshuaj tiv thaiv kev mob npaws, lub sijhawm koj kho Taltz. Txawm li cas los xij, cov tshuaj tiv thaiv tsis muaj zog yuav tsis ua haujlwm zoo ib yam li lawv tau ua. (Cov tshuaj tiv thaiv ua haujlwm los ntawm kev ua rau koj lub cev tiv thaiv kab mob los tsim cov tshuaj tiv thaiv kev tiv thaiv kev sib kis. Taltz yuav ua rau koj lub cev tsis muaj peev xwm ua cov tshuaj tiv thaiv.)

Yog tias koj tus kws kho mob xav kom koj siv tshuaj Taltz, nug seb koj puas siv sijhawm txhua cov tshuaj tiv thaiv zoo.

Taltz thiab tshuaj ntsuab thiab tshuaj ntxiv

Tsis muaj tshuaj ntsuab los yog tshuaj ntxiv uas tau qhia tshwj xeeb los cuam tshuam nrog Taltz. Tab sis nco ntsoov nrog koj tus kws muag tshuaj ua ntej siv ib qho.

Yuav ua li cas noj Taltz

Cov tshuaj yog muab los ntawm kev txhaj tshuaj hauv qab koj cov tawv nqaij (txhaj tshuaj subcutaneous). Koj tus kws kho mob yuav muab kev txhaj tshuaj rau koj thaum xub thawj. Tom qab ntawd lawv tuaj yeem qhia koj yuav ua li cas txhaj tshuaj rau koj tus kheej tom tsev. Koj tuaj yeem siv koj txoj kev txhaj tshuaj Taltz lub sijhawm twg los tau nyob rau hnub uas tau hais tseg.

Taltz los ua ib rab koob prefilled koob txhaj tshuaj thiab ua ib-siv prefilled autoinjector cwj mem. Nug koj tus kws kho mob uas yog qhov zoo tshaj rau koj. Ob daim ntawv puav leej muaj tib koob tshuaj. Koj txhaj tshuaj tag nrho thiab ces muab pov tseg tawm los yog xaum pov tseg autoinjector.

Thaum twg mam coj

Thaum koj yuav tsum tau noj tshuaj ntawm Taltz yog nyob ntawm tus mob uas raug kho. Feem ntau, koj yuav tau txais koj thawj koob tshuaj Taltz ntawm koj tus kws kho mob lub chaw haujlwm. Tom qab ntawd koj yuav tau muab kev txhaj tshuaj hauv qab no rau koj tus kheej.

Hauv qab no, peb piav qhia txog cov caij nyoog tshuaj noj rau Taltz rau nws qhov kev pom zoo siv.

  • Yog tias koj muaj psoriasis: Thawj koob tshuaj Taltz, koj yuav tau txais ob koob nyob rau tib hnub. Tom qab txhaj thawj zaug ntawm Taltz, koj yuav tau txhaj ib koob nyob rau txhua 2 asthiv rau 12 asthiv. Qhov no yuav ua raws li kev hno ib zaug txhua 4 lub lim tiam kom ntev li ntev tau uas koj tus kws kho mob pom zoo.
  • Yog tias koj muaj tus mob psoriatic: Thawj koob tshuaj Taltz, koj yuav tau txais ob koob nyob rau tib hnub. Tom qab txhaj thawj zaug ntawm Taltz, koj yuav tau txhaj ib koob nyob rau txhua 4 asthiv mus ntev npaum li kws kho mob hais.
  • Yog tias koj muaj psoriasis thiab mob caj dab: Koj yuav tau txais koob tshuaj Taltz raws li kev pom zoo noj tshuaj kom zoo txaus rau tus mob psoriasis, uas tau piav qhia saum toj no.
  • Yog tias koj muaj qhov tsis-radiographic axial spondyloarthritis (nr-axSpA): Tom qab koj koob thawj Taltz, koj yuav tau txhaj ib koob nyob rau txhua 4 asthiv.
  • Yog tias koj muaj mob ankylosing spondylitis (AS): Thawj koob tshuaj Taltz, koj yuav tau txais ob koob nyob rau tib hnub. Tom qab txhaj thawj zaug ntawm Taltz, koj yuav tau txhaj ib koob nyob rau txhua 4 asthiv.

Rau Taltz ua haujlwm tau zoo, nws yog qhov tseem ceeb yuav tau coj raws li koj tus kws kho mob tau sau tseg. Txhawm rau kom ntseeg tau tias koj nco qab noj tshuaj, nws yog ib lub tswv yim zoo kom koj sau koj lub sijhawm txhaj tshuaj rau hauv daim ntawv qhia hnub nyoog. Koj kuj tseem tuaj yeem siv lub cuab yeej ceeb toom tshuaj kom koj tsis txhob hnov ​​qab.

Nco tseg: Yog xav paub ntxiv txog cov xwm txheej teev tseg ntawm no, saib nqe lus “Taltz siv” ntu saud.

Yuav txhaj li cas

Koj tus neeg muab kev pab kho mob yuav qhia koj seb yuav siv rab koob txhaj tshuaj lossis lub cwj mem tsheb. Xav paub ntau ntxiv, cov yeeb yaj kiab thiab cov duab ntawm cov lus qhia txhaj tshuaj, saib lub tuam txhab cov vev xaib.

Nco ntsoov tias cov chaw tsim nyog txhawm rau txhaj Taltz yog sab xub ntiag ntawm koj tus ncej puab lossis koj lub plab (plab). Koj tseem tuaj yeem siv sab tom qab ntawm koj sab caj npab, tab sis koj yuav xav tau lwm tus neeg muab koj txhaj.

Yuav ua li cas Taltz ua haujlwm

Psoriasis, psoriatic mob caj dab, thiab spondyloarthritis yog autoimmune tej yam kev mob. Lawv ua rau koj lub cev tiv thaiv kab mob (koj lub cev tiv thaiv kab mob) tua cov hlwb noj qab nyob zoo.

Yog xav paub ntxiv txog cov xwm txheej no, saib hauv seem “Taltz siv” ntu saud.

Ntau qhov chaw ntawm lub cev muaj zog koom nrog hauv txhua ntawm cov xwm txheej no. Ib qho tshwj xeeb cov txheej txheem tau ua nrog cov protein hu ua interleukin-17A. Cov protein no qhia rau koj lub cev tiv thaiv cov leeg mob ntawm koj cov tawv nqaij thiab pob qij txha.

Taltz muaj ixekizumab, uas yog ib hom tshuaj hu ua human monoclonal antibody. Nws ua haujlwm los ntawm khi (txuas ntxiv) rau interleukin-17A. Los ntawm kev ua qhov no, Taltz thaiv qhov kev txiav txim ntawm cov protein. Nws nres nws los ntawm kev qhia koj lub cev tiv thaiv kab mob mus tua cov hlwb hauv koj cov tawv nqaij thiab pob qij txha.

Los ntawm kev tiv thaiv koj lub cev los ntawm kev tawm tsam cov hlwb, Taltz pab:

  • txo qhov tsim ntawm cov quav hniav ntawm koj cov tawv nqaij hauv cov quav hniav psoriasis
  • txo qhov mob o (o) ntawm koj cov pob qij txha hauv kev mob caj dab, tsis muaj radiographic axial spondyloarthritis, thiab nquag ua paug rau pob qij txha

Yuav siv sijhawm ntev npaum li cas ua haujlwm?

Taltz pib ua haujlwm kom sai li sai tau thaum koj pib kho. Txawm li cas los xij, nws yuav siv sijhawm li ob peb lub lis piam rau koj kom pom cov kev hloov pauv.

Hauv cov kev tshawb fawb soj ntsuam, feem ntau cov neeg muaj quav hniav mob psoriasis tau pom meej los yog yuav luag zoo ntawm daim tawv nqaij 12 lub lis piam tom qab lawv pib kho los yog ntxov dua. Thiab li ntawm ib nrab ntawm cov neeg muaj mob caj dab psoriatic uas coj Taltz muaj cov kev mob tshwm sim tsawg dua thiab ua rau lub cev zoo dua qub los ntawm 12 lub lis piam tom qab pib kho.

Kev tshawb fawb soj ntsuam ntawm cov neeg laus uas tsis yog-radiographic axial spondyloarthritis saib kev kho Taltz thiab kho nrog cov placebo. (Ib qho tshuaj placebo yog ib txoj kev kho mob uas tsis muaj tshuaj.) Tom qab 52 lub lim tiam ntawm kev kho mob, 30% ntawm cov neeg siv Taltz muaj lawv cov tsos mob txo los ntawm 40% ntau dua. Hauv kev sib piv, 13% ntawm cov tib neeg siv cov placebo muaj tib lub txiaj ntsig.

Ob qhov kev tshawb fawb soj ntsuam ntawm cov neeg laus uas muaj tus kab mob pob qij txha caj qaum ntsia kev kho mob nrog Taltz piv nrog cov placebo. Tom qab 16 lub lis piam ntawm kev kho mob, 25% mus rau 48% ntawm cov neeg siv Taltz muaj lawv cov tsos mob txo los ntawm 40% lossis ntau dua. Hauv kev sib piv, 13% mus rau 18% ntawm cov tib neeg siv cov placebo muaj tib lub txiaj ntsig.

Taltz thiab cev xeeb tub

Taltz tsis tau kawm txog cov poj niam cev xeeb tub, yog li nws tsis paub meej tias cov tshuaj no muaj kev nyab xeeb thaum cev xeeb tub.

Nco ntsoov qhia koj tus kws kho mob yog tias koj xeeb tub los yog tab tom npaj lub cev xeeb tub ua ntej koj pib kho. Yog koj xav tias koj tuaj yeem cev xeeb tub thaum noj Taltz, tham nrog koj tus kws kho mob tam sim ntawd.

Taltz thiab txwv tsis pub muaj menyuam

Nws tsis paub meej yog tias Taltz muaj kev nyab xeeb noj thaum cev xeeb tub. Yog tias koj tau sib deev thiab koj lossis koj tus khub tuaj yeem cev xeeb tub, tham nrog koj tus kws kho mob txog kev xav tswj tsis pub muaj menyuam thaum koj siv Taltz.

Yog xav paub ntxiv txog kev noj Taltz thaum cev xeeb tub, mus saib hauv ntu "Taltz thiab cev xeeb tub" saum toj no.

Taltz thiab pub niam mis

Nws tsis paub yog tias Taltz nkag mus rau leej niam cov kua mis lossis yog nws cuam tshuam rau koj lub cev ua kua mis. Taltz tau pom hauv niam cov kua mis hauv kev tshawb fawb tsiaj, tab sis kev tshawb fawb hauv tsiaj tsis nco ntsoov muaj dab tsi tshwm sim hauv tib neeg.

Yog tias koj pub mis niam thiab xav noj Taltz, tham nrog koj tus kws kho mob. Lawv tuaj yeem sib tham txog qhov yuav muaj feem thiab cov txiaj ntsig zoo ntawm cov tshuaj nrog koj.

Cov lus nug nquag hais txog Taltz

Nov yog cov lus teb rau qee cov lus nug nquag txog Taltz.

Taltz puas yog roj ntsha?

Yog lawm. Taltz yog ib qho tshuaj lom biologic. Qhov no txhais tau hais tias nws yog cov tshuaj uas ua los ntawm cov protein thiab tsis yog los ntawm cov tshuaj (zoo li feem ntau cov tshuaj yog). Kev siv tshuaj lom neeg yog tsim hauv ib lub lab siv tsiaj hlwb.

Kuv puas tseem yuav tsum tau siv cov tshuaj pleev pleev rau cov kab mob psoriasis thaum siv Taltz?

Tej zaum. Tab sis koj yuav tsum ua raws koj tus kws kho mob cov lus qhia txog qhov no.

Yog tias koj cov tawv nqaij puas ntshiab tom qab siv Taltz, tom qab ntawv koj tsis tas yuav tsum siv tshuaj pleev ntev dua. Tab sis qee kis, koj tseem yuav muaj qee cov psoriasis plaques (tuab, liab, plooj txaij ntawm koj cov tawv nqaij). Yog tias qhov no tshwm sim, koj tus kws kho mob yuav qhia koj kom siv cov tshuaj pleev kom ntub lossis lwm yam tshuaj pleev raws li qhov xav tau. Nco ntsoov ua raws cov lus qhia uas koj tus kws kho mob muab rau koj.

Siv Taltz puas tuaj yeem ua rau muaj mob tshiab lossis cov phom sij huam mob plab hnyuv?

Yog lawm nws tuaj yeem, txawm hais tias qhov no tsis tshua muaj. Voos kab mob ua paug (IBD) yog ib pawg kab mob uas ua mob o (o) hauv koj cov hnyuv. Cov kab mob no suav nrog Crohn's disease thiab ulcerative colitis.

Hauv cov kev tshawb fawb soj ntsuam, Crohn tus kab mob tau tshwm sim hauv 0.1% ntawm cov neeg mob plaque psoriasis uas tau txais Taltz. Ulcerative colitis tau tshwm sim nyob rau hauv 0.2% ntawm cov neeg muaj plaque psoriasis uas tau txais Taltz.

Yog tias koj muaj cov tsos mob tshiab lossis phem dua ntawm IBD, mus ntsib koj tus kws kho mob. Cov tsos mob tuaj yeem suav nrog mob hauv koj lub plab (plab), raws plab nrog lossis tsis muaj ntshav, thiab poob phaus.

Kuv tuaj yeem ua dab tsi los tiv thaiv tus kab mob thaum kuv noj Taltz?

Taltz tuaj yeem ua rau tsis muaj zog ntawm koj lub cev tsis muaj zog, yog li cov tshuaj muaj peev xwm nce koj qhov kev pheej hmoo kis mob. Nov yog qee cov lus qhia los pab ua kom koj muaj zog tiv thaiv kab mob thiab pab koj kom tsis txhob kis kab mob:

  • Ua ntej koj pib txoj kev kho mob, tham nrog koj tus kws kho mob txog kev kho tshiab nrog kev txhaj tshuaj tiv thaiv kab mob uas pom zoo.
  • Ntxuav koj ob txhais tes tsis tu ncua, tshwj xeeb yog tias koj tau nyob hauv ib qho chaw pej xeem.
  • Sim ua kom tsis txhob nyob ze nrog cov neeg muaj kab mob, tshwj xeeb yog hnoos, mob khaub thuas, lossis mob khaub thuas.
  • Zam kev muab phuam los yog phuam ntxuav muag nrog ib tus neeg uas muaj kab mob voos lossis tawv nqaij mob.
  • Noj zaub mov zoo.
  • Pw kom txaus.
  • Tsis txhob haus luam yeeb.

Puas yog Taltz kho tau cov quav hniav psoriasis lossis mob caj pas?

Tsis tau, Taltz tsis muaj kev kho cov mob no. Tam sim no tseem tsis muaj kev kho tus mob quav hniav los sis mob caj pas. Tab sis kev kho mus ntev nrog Taltz yuav pab tswj cov tsos mob ntawm cov mob no.

Cov chaw kho mob tshawb xyuas cov neeg uas muaj plaque psoriasis uas coj Taltz. Qee tus neeg cov tsos mob ploj tag lossis dhau los ua neeg me tom qab 12 asthiv. Ib nrab ntawm pab pawg no tom qab ntawd coj Taltz ntxiv rau 48 lub lis piam. Lwm ib nrab ntawm cov neeg coj cov tshuaj placebo (tsis kho) rau 48 lub lis piam.

Ntawm cov neeg uas tau noj Taltz, 75% tseem tsis muaj lossis tsuas yog muaj cov tsos mob me los ntawm txoj kev tshawb no tag. Rau feem ntau ntawm cov tib neeg uas tau noj cov placebo, lawv cov tsos mob tau mob ntau dua. Tsuas yog 7% ntawm cov placebo pawg tsis muaj lossis cov tsos mob me. Lub sijhawm nruab nrab nws tau siv rau cov tsos mob rau mob hnyav dua rau cov neeg uas tau noj cov placebo yog 164 hnub. Tab sis thaum lawv rov qab noj Taltz, rau 66% ntawm cov neeg no, lawv cov psoriasis tshem tawm hauv 12 lub lis piam.

Taltz cov kev ceev faj

Ua ntej noj Taltz, nrog koj tus kws kho mob hais txog koj li keeb kwm kev noj qab haus huv. Taltz yuav tsis haum rau koj yog tias koj muaj qee yam mob. Cov no suav nrog:

  • Ib qho kev kis mob, tab sis kev mob ntsws tshwj xeeb. Taltz tuaj yeem ua rau koj lub cev tiv thaiv kab mob tsis tuaj yeem tawm tsam cov kab mob, yog li kev kis mob xws li mob ntsws (TB) tuaj yeem dhau los ua neeg mob hnyav.
    • Yog tias koj tam sim no muaj TB lossis muaj TB yav dhau los, koj yuav tsum tau noj tshuaj los kho nws. Thaum kho tau tus mob TB, tej zaum koj yuav pib noj Taltz.
    • Yog tias koj muaj cov tsos mob ntawm lwm yam kab mob, xws li ua npaws, lossis yog koj kis tau tus kab mob uas pheej rov qab tuaj, qhia koj tus kws kho mob. Cov mob no yuav tsum tau kho ua ntej koj tuaj yeem pib kho nrog Taltz.
  • Cov mob ntawm txoj hnyuv. Muaj qee zaus, Taltz tuaj yeem paug cov tsos mob ntawm tus mob raws plab hnyuv (IBD). IBD yog ib pawg kab mob uas suav nrog Crohn's mob thiab mob plab hlaub. Yog tias koj muaj IBD, tham nrog koj tus kws kho mob. Lawv yuav soj ntsuam koj cov tsos mob thaum koj noj Taltz. Yog tias koj IBD poob qis, koj yuav tsum tau txwv Taltz. Muaj lwm cov tshuaj xyoob ntoo uas tsis ua rau IBD haj yam tsis zoo uas koj tuaj yeem sim ua.

Nco tseg: Yog xav paub ntxiv txog cov kev pheej hmoo tsis zoo ntawm Taltz, saib nqe lus "Taltz phiv" saum toj no.

Taltz noj ntau dhau

Txhua daim ntawv xaum thiab lub npov autoinjector cwj mem muaj qhov tshuaj zoo rau ib koob. Yog li kev siv tshuaj ntau dhau tsuas yog ua tau yog tias koj muab koj tus kheej ntau yam tshuaj lossis yog tias koj noj Taltz ntau dhau.

Tshuav cov tsos mob

Cov tsos mob ntawm kev noj haus ntau dhau yuav suav nrog cov kev mob tshwm sim ntau dua lossis ntau dua, xws li:

  • cov kab mob sab sauv, xws li mob khaub thuas
  • xeev siab
  • mob ua npaws, yam li ncaws pob ko taw
  • kev fab tshuaj hnyav heev
  • cov mob ua paug plob tsis so tswj (IBD), xws li Crohn's mob lossis mob plab nyhuv
  • muaj feem ntau ntawm cov mob, xws li mob ntsws (TB)

Dab tsi yog qhov ua txhaum cai dhau

Yog koj xav tias koj tau noj ntau dhau ntawm cov tshuaj no, hu rau koj tus kws kho mob. Koj kuj tuaj yeem hu xov tooj rau Asmeskas Lub Koom Haum Saib Xyuas Kev Lom Lom ntawm 800-222-1222 lossis siv lawv qhov online. Tab sis yog tias koj cov tsos mob hnyav, hu 911 lossis mus rau chav kho mob ze tshaj plaws tam sim ntawd.

Taltz tas sijhawm, cia khoom thiab pov tseg

Thaum koj tau txais Taltz los ntawm lub tsev muag tshuaj, tus kws muag tshuaj yuav ntxiv hnub tas sijhawm rau cov npe ntawm lub raj mis. Hnub no feem ntau yog 1 xyoos suav txij hnub lawv xa cov tshuaj mus.

Lub hnub tas sij hawm pab lav qhov ua tau zoo ntawm cov tshuaj thaum lub sijhawm no. Txoj cai tam sim no ntawm Lub Chaw Tswj Xyuas Khoom Noj thiab Tshuaj (FDA) yog kom tsis txhob siv cov tshuaj uas tas sij hawm. Yog tias koj tsis tau siv cov tshuaj uas dhau lub hnub tas sij hawm tas sij hawm, nug koj tus kws muag tshuaj seb koj puas tseem siv tau cov tshuaj no.

Cia

Ntev ntev npaum li cas cov tshuaj tseem tuaj yeem nyob ntawm ntau yam, nrog rau seb koj khaws cov tshuaj li cas thiab nyob qhov twg.

Taltz prefilled koob txhaj tshuaj thiab autoinjector cwjmem yuav tsum tau muab cia rau hauv lub tub yees ntawm 36 ° F rau 46 ° F (2 ° C txog 8 ° C). Nco ntsoov tias lawv tsis nyob ntawm qhov chaw ncav cuag menyuam yaus. Tsis txhob khov Taltz. Thiab tsis txhob siv cov tshuaj yog tias nws khov.

Muaj qee kis, koj yuav tsum tau coj Taltz tawm ntawm lub tub yees ua ntej siv nws. Piv txwv li, yog tias koj mus ob peb hnub thiab yuav tsum tau txhaj tshuaj rau lub sijhawm ntawd. Paub tias koj tuaj yeem cia Taltz nyob rau hauv chav tsev kub txog li 86 ° F (30 ° C) txog li 5 hnub.

Nco ntsoov khaws cov koob txhaj tshuaj lossis autoinjector cwj mem rau hauv nws cov thawv thawj kom tiv thaiv nws ntawm lub teeb. Yog tias koj tsis siv lub koob txhaj tshuaj los yog cwj mem tsis pub dhau 5 hnub, koj yuav tsum tau muab pov tseg yam tsis muaj kev phom sij. Koj tsis txhob muab Taltz rov qab tso rau hauv lub tub yees thaum uas tau muab khaws cia ntawm chav sov.

Pov tseg

Tom qab koj tau siv lub Taltz prefilled syringe lossis autoinjector cwjmem, muab tso rau hauv FDA-pom zoo cov khoom ntim pov tseg. Qhov no pab tiv thaiv lwm tus, suav nrog cov menyuam yaus thiab cov tsiaj hauv tsev, los ntawm kev noj tshuaj. Nws tseem yuav pab kom cov tshuaj ua rau muaj kev puas tsuaj ib puag ncig thiab.

Yog tias koj tsis muaj cov thawv ntim khoom ntse, koj tuaj yeem yuav hauv online ntawm chaw muag tshuaj hauv koj lub nroog.

Koj tuaj yeem nrhiav cov lus qhia tseem ceeb ntawm cov tshuaj pov tseg ntawm no. Koj tseem tuaj yeem nug koj tus kws muag tshuaj kom muab cov lus qhia txog kev pov tseg koj cov tshuaj.

Cov ntaub ntawv tshaj lij rau Taltz

Cov ntaub ntawv hauv qab no yog muab rau cov kws kho mob thiab lwm tus kws kho mob.

Cov Khoom Qhia

Lub Chaw Tswj Xyuas Khoom Noj thiab Tshuaj (FDA) tau pom zoo Taltz los kho:

  • nqaj nruab nrab mus rau qhov hnyav txha hniav mob psoriasis uas tsim nyog rau kev kho mob los sis kho duab ci; Rau kev siv no, cov tshuaj yuav raug siv rau cov neeg laus thiab menyuam yaus hnub nyoog 6 xyoo thiab laus dua
  • nquag ua haujlwm mob psoriatic mob caj dab hauv cov neeg laus
  • non-radiographic axial spondyloarthritis (nr-axSpA) hauv cov neeg laus
  • nquag ankylosing spondylitis (AS), uas tseem hu ua radiographic axial spondyloarthritis (r-axSpA); rau kev siv no, cov tshuaj tuaj yeem ua raws cai rau cov laus

Mechanism ntawm kev ua

Taltz muaj cov ixekizumab, uas yog ib qho tshuaj tiv thaiv pej xeem IgG monoclonal antibody. Ixekizumab xaiv cov hom phiaj thiab khi rau interleukin-17A (IL-17A). IL-17A yog ib qho ntawm cov cytokines uas paub tias yuav koom nrog tsim cov tshuaj tiv thaiv thiab ua kom lub cev tsis muaj zog uas ua rau mob psoriatic thiab mob ankylosing spondylitis. Los ntawm khi rau IL-17A, ixekizumab nres nws los ntawm kev sib cuam tshuam nrog IL-17A receptor thiab yog li inhibits cov lus teb no.

Pharmacokinetics thiab cov metabolism

Ixekizumab bioavailability muaj li ntawm 60% mus rau 81% tom qab txhaj tshuaj subcutaneous hauv cov quav hniav psoriasis kev tshawb nrhiav. Txoj kev siab dua ntawm kev nyab xeeb tau ua tiav los ntawm kev txhaj tshuaj hauv tus ncej piv rau lwm qhov chaw txhaj tshuaj xws li sab caj npab thiab plab.

Qhov nruab nrab ib nrab-lub neej yog 13 hnub nyob rau hauv kev kawm nrog cov quav hniav psoriasis.

Lub metabolic tua txoj hauv kev tseem tsis tau pom, tab sis nws cia siab tias yuav zoo ib yam li cov ntawm endogenous IgG nrog cov kab mob catabolic uas ua cov peptides me me thiab cov amino acids.

Cov Yuav Tsum Tau Ua

Taltz yog contraindicated rau hauv cov neeg uas muaj kev cuam tshuam rau kev mob siab dhau los, xws li anaphylaxis, rau ixekizumab lossis nws qhov tshwj xeeb.

Cia

Lub Taltz autoinjector thiab koob txhaj tshuaj yuav tsum muab cia rau hauv tub yees li ntawm 36 ° F mus rau 46 ° F (2 ° C txog 8 ° C).

Tsis khov. Tiv thaiv ntawm lub teeb. Tsis txhob co. Taltz tuaj yeem khaws cia hauv chav tsev qhov kub txog li 86 ° F (30 ° C) txog li 5 hnub. Thaum muab cia hauv chav sov, nws yuav tsum tsis txhob muab tso rau hauv tub yees.

Tsis lees paub: Cov Xov Xwm Kho Mob Niaj Hnub no tau ua txhua yam kom paub tseeb tias txhua yam ntaub ntawv yog qhov tseeb, raug, thiab dhau mus. Txawm li cas los xij, cov kab lus no yuav tsum tsis txhob siv los hloov chaw rau qhov kev paub thiab kev paub ntawm tus neeg muaj ntawv tso cai kho mob. Koj yuav tsum tau sab laj nrog koj tus kws kho mob lossis lwm tus kws saib xyuas kev noj qab haus huv ua ntej noj tshuaj. Cov ntaub ntawv tshuaj muaj nyob ntawm no yuav raug hloov thiab tsis yog npaj rau txhua txoj kev siv, cov lus qhia, kev ceev faj, ceeb toom, kev cuam tshuam nrog tshuaj, kev fab tshuaj, lossis muaj kev cuam tshuam tsis zoo. Qhov tsis muaj lus ceeb toom lossis lwm cov ntaub ntawv rau kev muab tshuaj tsis qhia tias kev sib txuam tshuaj lossis tshuaj muaj kev nyab xeeb, siv tau, lossis tsim nyog rau txhua tus neeg mob lossis txhua qhov siv tshwj xeeb.

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