Tus Sau: Randy Alexander
Hnub Kev Tsim: 24 Lub Plaub Hlis Ntuj 2021
Hloov Hnub: 1 Lub Kaum Ib Hli Ntuj 2024
Anonim
Pharmacology - Glucocorticoids
Daim Duab: Pharmacology - Glucocorticoids

Zoo Siab

Txheej txheem cej luam

Ntau yam teeb meem kev noj qab haus huv txuam nrog o. Glucocorticoids ua hauj lwm zoo rau kev ua kom tsis txhob muaj kev puas tsuaj los ntawm ntau yam kev tiv thaiv kab mob hauv lub cev. Cov tshuaj no tseem muaj ntau yam siv. Txawm li cas los xij, lawv tseem tuaj nrog kev phiv. Cov no tuaj yeem mob hnyav, tshwj xeeb yog tias koj siv cov tshuaj no ntev dhau.

Glucocorticoids yog dab tsi?

Cov tshuaj Glucocorticoid yog neeg tsim cov glucocorticoids, cov tshuaj steroids uas tshwm sim hauv koj lub cev. Lawv muaj ntau lub zog. Ib qho yog los cuam tshuam tus mob los ntawm kev tsiv mus rau hauv cov hlwb thiab txhawb cov protein tawm mus kom txhawb qhov o. Lawv kuj tseem pab koj lub cev teb rau kev ntxhov siab thiab kev tswj hwm seb koj lub cev siv cov rog thiab qab zib li cas.

Vim tias glucocorticoids muaj ntau lub luag haujlwm, tib neeg tsim lossis hluavtaws glucocorticoids tau tsim los pab kho ntau yam mob.

Daim ntawv teev cov tshuaj glucocorticoid

Piv txwv ntawm cov tshuaj glucocorticoid suav nrog:

  • beclomethasone
  • betamethasone
  • budesonide
  • cortisone
  • dexamethasone
  • hydrocortisone
  • methylprednisolone
  • prednisolone
  • prednisone
  • triamcinolone

Cov tshuaj glucocorticoids kho zoo li cas

Synthetic glucocorticoids tuaj yeem muaj zog ntau dua li cov tshuaj pleev ib ce txawv. Lawv raug siv los kho ntau yam mob.


Autoimmune ntshawv siab

Cov kab mob autoimmune tuaj yeem ua rau ntau qhov kev puas tsuaj los ntawm o thaum lub cev yuam kev rau nws tus kheej. Cov kab mob autoimmune suav nrog:

  • ntau yam sclerosis
  • rheumatoid mob caj dab
  • inflammatory plob tsis so tswj kab mob
  • ulcerative mob plab
  • psoriasis
  • eczema

Glucocorticoids tuaj yeem txo cov kev ua haujlwm ntawm lub cev tiv thaiv kab mob. Qhov no pab txo qhov kev puas sab hauv los ntawm cov kab mob no. Lawv txwv qhov o ntawm autoimmune kev tsis haum. Qhov no tuaj yeem txo qhov mob, o, mob nqaij thiab khaus.

Ua xua thiab hawb pob

Ua xua thiab hawb pob yog tej yam mob uas koj lub cev tiv thaiv tau cov tshuaj phem tsis haum. Hauv cov xwm txheej no, cov tshuaj xws li paj ntoos los yog txiv laum huab xeeb tuaj yeem ua rau muaj kev tsis haum tshuaj. Cov tsos mob tuaj yeem sib txawv thiab muaj xws li:

  • khaus
  • khaus, lub qhov muag daj
  • lub teeb ci ntsa iab
  • liab, khaus, lossis tawm pob
  • txham thiab txhaws ntswg los ntswg
  • o koj lub ntsej muag, di ncauj, lossis caj pas
  • teeb meem ua pa

Glucocorticoids tuaj yeem kho qhov kev tiv thaiv no los ntawm kev txiav tawm qhov mob thiab ua kom lub cev tsis muaj zog tiv thaiv kab mob.


Adrenal tsis txaus

Yog tias koj muaj adrenal tsis txaus, koj lub cev tsis tuaj yeem tsim cortisol txaus. Qhov no tuaj yeem yog qhov tshwm sim ntawm kev mob xws li Addison's kab mob lossis tshem tawm phais koj cov qog adrenal. Glucocorticoids tuaj yeem siv los hloov cortisol uas koj lub cev tsis tuaj yeem ua.

Lub plawv tsis ua hauj lwm

Kev siv sijhawm luv luv (tsawg dua 7 hnub) ntawm glucocorticoids tuaj yeem pab kho plawv tsis ua los ntawm kev ua kom koj lub cev muaj peev xwm teb rau qee cov tshuaj diuretics. Txawm li cas los xij, qhov no tsis yog qhov siv ntau.

Mob Cancer

Glucocorticoids tuaj yeem siv kho mob qog nqaij hlav kom txo qee qhov kev mob tshwm sim ntawm kev siv tshuaj khomob. Lawv kuj tseem siv tau los tua qee cov qog nqaij hlav cancer hauv qee qhov mob qog nqaij hlav, suav nrog:

  • mob ntsws ua kom mob ntshav siab
  • mob qog ua kua ntshav siab
  • Hodgkin lymphoma
  • Tsis-Hodgkin lymphoma
  • ntau myeloma

Daim tawv nqaij mob

Cov tawv nqaij mob txij li eczema mus rau tshuaj lom ivy yog kho nrog glucocorticoids. Cov no suav nrog tshuaj noj hauv khw thiab tshuaj pleev cov tshuaj pleev uas koj siv rau koj cov tawv nqaij thiab tshuaj uas koj noj ntawm qhov ncauj.


Kev phais mob

Glucocorticoids tej zaum yuav siv thaum lub hlwb tsis hnov ​​qab. Lawv txo qhov mob hauv cov nqaij mos. Lawv kuj raug tso cai tom qab hloov khoom nruab nrog cev los pab tiv thaiv kom tsis txhob muaj zog tiv thaiv kab mob hauv lub cev.

Sab sij huam

Glucocorticoids yuav zoo li cov tshuaj muaj txiaj ntsig zoo, tab sis lawv kuj muaj cov kev mob tshwm sim. Qee qhov kev mob tshwm sim no tuaj yeem ua kom puas tsuaj tau. Vim li no cov tshuaj no tsis tau teev tseg rau siv ntev.

Cov tshuaj no tuaj yeem:

  • nce koj cov ntshav qab zib kom nyob zoo, uas tuaj yeem ua ntshav qab zib ib ntus thiab tej zaum ua rau muaj ntshav qab zib ntev
  • txwv koj lub cev kev muaj peev xwm nqus cov calcium, uas tuaj yeem ua rau txha osteoporosis
  • nce koj cov roj (cholesterol) thiab triglyceride ntau ntau
  • nce koj qhov kev pheej hmoo ntawm mob rwj thiab mob plab zom mov
  • ncua qhov txhab kho kom zoo, uas yuav tsum muaj qee qhov mob
  • txwv koj muaj zog tiv thaiv kab mob thiab ua rau koj muaj kab mob kis tau yooj yim dua

Kev siv ntev ntev ntawm glucocorticoids tuaj yeem ua rau poob ntawm cov leeg. Nws kuj tuaj yeem ua rau Cushing's syndrome, uas tuaj yeem ua rau:

  • rog rog ntawm koj lub xwb pwg
  • puag ncig lub ntsej muag
  • hnyav
  • paj yeeb ncab
  • cov pob txha tsis muaj zog
  • mob ntshav qab zib
  • ntshav siab
  • nyias daim tawv
  • kho maj mam zoo
  • pob txuv
  • ntawm cev ntas tsis ntas
  • txo qis libido
  • nkees
  • kev nyuaj siab

Yog tias koj tau siv glucocorticoids ntau dua li ob peb lub lis piam, koj tus kws kho mob feem ntau yuav txo qis koj cov tshuaj kom maj mam es tsis yog koj tsum tsis noj tam sim ntawd. Qhov no pab txhawm rau tiv thaiv kev thim tawm. Koj lub cev ib txwm ua rau glucocorticoids, tab sis thaum koj pib noj lawv raws li kev siv tshuaj, koj lub cev hnov ​​mob los ntawm kev ua kom tsawg dua ntawm nws tus kheej. Thaum koj tsum tsis noj cov tshuaj glucocorticoids, koj lub cev xav tau sijhawm los pib ua nws tus kheej ntau dua li qub.

Tham nrog koj tus kws kho mob

Glucocorticoids tuaj yeem yog cov tshuaj siv rau ntau yam kev kho mob. Txawm li cas los xij, nws yog ib qho tseem ceeb kom sib npaug qhov xav tau ntawm kev kho glucocorticoid tiv thaiv cov kev mob tshwm sim. Yog tias koj tus kws kho mob tau sau ntawv rau kev kho glucocorticoid rau koj, qhia lawv txog cov kev mob tshwm sim uas koj muaj. Nws kuj tseem ceeb uas yuav tsum noj cov tshuaj raws nraim li qhia, suav nrog thaum koj tsum txiav. Koj tus kws kho mob yuav txiav koj cov tshuaj tawm maj mam kom tiv thaiv kev thim rov qab.

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