Dawb txoj saw saw

Zoo Siab

• Lub teeb dawb sib txuas yog dab tsi?
• Nws siv rau dab tsi?
• Vim li cas kuv thiaj xav tau lub teeb ntsuas dawb lub teeb kuaj?
• Dab tsi tshwm sim thaum kuaj lub teeb pom kev ua pub dawb?
• Kuv puas yuav tau ua ib yam dab tsi txhawm rau npaj rau qhov kev xeem?
• Puas muaj kev pheej hmoo rau kev kuaj lub teeb ua saw dawb?
• Cov txiaj ntsig li cas?
• Puas muaj lwm yam ntxiv uas kuv xav paub txog kev kuaj xyuas lub teeb dawb dawb?
• Ua tim khawv

Lub teeb dawb sib txuas yog dab tsi?

Cov hlua khi cov me nyuam yog cov protein tsim los ntawm cov ntshav ntshav, uas yog hom qe ntshav dawb. Plasma cell kuj ua rau cov tshuaj tiv thaiv kab mob ntshav (tshuaj tiv thaiv). Immunoglobulins pab tiv thaiv lub cev tiv thaiv kev mob thiab kis mob. Immunoglobulins tau tsim thaum cov hlua khi txuas nrog cov chains hnyav, lwm hom protein. Thaum cov saw hlau sib txuas nrog cov saw hnyav, lawv muaj lub npe hu ua ua txhua yam txoj sia sib txuas.

Feem ntau, ntshav hlwb ua ib feem me me ntawm cov hlua txuas ntxiv uas tsis txuas nrog txoj sia hnyav. Lawv raug tso tawm mus rau hauv cov hlab ntshav. Cov saw hlau tsis muaj kab paub yog hu ua pub dawb txoj sia sib txuas.

Muaj ob hom kev sib txuas cov teeb ci: lambda thiab kappa lub saw sib txuas. Kev ntsuam xyuas lub teeb ci dawb ua rau ntsuas cov nuj nqi ntawm lambda thiab kappa txoj hlua khi dawb hauv cov ntshav. Yog tias cov nyiaj ntawm cov saw dawb dawb dua lossis qis dua li qub, nws tuaj yeem txhais tau tias koj muaj kev tsis txaus siab ntawm cov ntshav ntshav. Cov no suav nrog ntau yam mob myeloma, mob qog nqaij hlav ntshav, thiab amyloidosis, uas yog ib qho mob uas ua rau muaj protein ntau hauv cov nqaij nruab nrog cev thiab nqaij sib txawv.

Lwm lub npe: dawb kappa / lambda piv, kappa / lambda quantitative free teeb, freelite, kappa thiab lambda dawb lub teeb saw, immunoglobulin dawb lub teeb txuas

Nws siv rau dab tsi?

Kev ntsuas lub teeb dawb siv yog siv los pab kuaj mob lossis saib xyuas ntshav muaj ntshav tsis zoo.

Vim li cas kuv thiaj xav tau lub teeb ntsuas dawb lub teeb kuaj?

Koj yuav xav tau qhov kev ntsuas no yog tias koj muaj cov tsos mob ntawm tus mob ntshav tes txav ntshav. Nyob ntawm seb qhov teeb meem ntshav puas tuaj yeem koj muaj thiab hom kabmob twg cuam tshuam, koj cov tsos mob yuav suav nrog:

• Mob pob txha
• Nkees
• Looj tes lossis tingling hauv caj npab thiab txhais ceg
• Nplaig o
• Purple me ntsis ntawm daim tawv nqaij

Dab tsi tshwm sim thaum kuaj lub teeb pom kev ua pub dawb?

Tus kws kho mob yuav kuaj ntshav ntawm txoj hlab ntshav hauv koj txhais caj npab, siv rab koob me me. Tom qab cov koob raug tso nkag, cov ntshav me me yuav raug sau rau hauv lub khob kuaj lossis vial. Koj tuaj yeem hnov ​​me ntsis thaum cov koob nkag mus lossis tawm. Qhov no feem ntau yuav siv sijhawm tsawg dua tsib feeb.

Kuv puas yuav tau ua ib yam dab tsi txhawm rau npaj rau qhov kev xeem?

Koj tsis tas yuav tsum tau npaj tshwj xeeb rau txoj kev ntsuas cov hlua dawb.

Puas muaj kev pheej hmoo rau kev kuaj lub teeb ua saw dawb?

Txoj kev kuaj ntshav muaj feem me me. Koj yuav muaj mob me lossis doog ntshav ntawm qhov chaw tso rab koob, tab sis feem ntau cov tsos mob ploj mus sai.

Cov txiaj ntsig li cas?

Koj cov txiaj ntsig yuav qhia cov nuj nqis rau lambda thiab kappa dawb sib txuas. Nws tseem yuav muab qhov sib piv ntawm ob qho. Yog tias koj cov txiaj ntsim tau tsis zoo, nws yuav txhais tau tias koj muaj teeb meem ntshav plasma cell, xws li:

• Ntau myeloma
• Mob Amyloidosis
• MGUS (monoclonal gammopathy ntawm qhov tsis paub qhov tseem ceeb). Qhov no yog qhov mob uas koj muaj cov protein ntau tsis txaus. Nws feem ntau ua rau tsis muaj teeb meem lossis cov tsos mob, tab sis qee zaus nws pib mus rau ntau lub myeloma.
• Waldenstrom macroglobulinemia (WM), mob cancer ntawm cov qe ntshav dawb. Nws yog hom ntawm hom tsis-Hodgkin lymphoma.

Kawm paub ntau ntxiv txog cov kev sim hauv chaw soj ntsuam, cov chaw siv ntsuas, thiab nkag siab cov txiaj ntsig tau.

Puas muaj lwm yam ntxiv uas kuv xav paub txog kev kuaj xyuas lub teeb dawb dawb?

Kev ntsuam xyuas lub teeb dawb dawb feem ntau yog xaj nrog rau lwm yam kev kuaj, suav nrog kev kuaj ntshav txhaj tshuaj, kom pab pom tseeb lossis txiav txim tawm tus mob.

Ua tim khawv

1. American Cancer Society [Internet]. Atlanta: American Cancer Society Inc .; c2019. Kev Ntsuam Xyuas Yuav Pom Ntau Yam Myeloma; [kho tshiab 2018 Feb 28; hais tawm 2019 Dec 21]; [txog 4 ntxaij]. Muaj los ntawm: https://www.cancer.org/cancer/multiple-myeloma/detection-diagnosis-staging/testing.html
2. American Cancer Society [Internet]. Atlanta: American Cancer Society Inc .; c2019. Waldenstrom Macroglobulinemia yog dab tsi ?; [kho tshiab 2018 Jul 29; hais tawm 2019 Dec 21]; [txog 3 ntxaij]. Muaj los ntawm: https://www.cancer.org/cancer/waldenstrom-macroglobulinemia/about/what-is-wm.html
3. American Society of Hematology [Internet]. Washington D.C .: Asmeskas haiv neeg Hematology; c2019. Myeloma; [hais tawm 2019 Dec 21]; [txog 3 ntxaij]. Muaj los ntawm: https://www.hematology.org/Patients/Cancers/Myeloma.aspx
4. International Myeloma Foundation [Is Taws Nem]. North Hollywood (CA): International Myeloma Foundation; Nkag Siab Freelite thiab Hevylite Cov Kev Ntsuas; [hais tawm 2019 Dec 21]; [txog 3 ntxaij]. Muaj los ntawm: https://www.myeloma.org/sites/default/files/resource/u-freelite_hevylite.pdf
5. Kev Tshuaj Ntsuam Xyuas online [Internet]. Washington D.C .: Koom Haum Asmeskas Rau Chaw Kuaj Mob; c2001–2019. Ntshav Ntshav Dawb Lub Teeb; [kho tshiab 2019 Oct 24; hais tawm 2019 Dec 21]; [txog 2 ntxaij]. Muaj los ntawm: https://labtestsonline.org/tests/serum-free-light-chains
6. Mayo Clinic [Internet]. Mayo Foundation for Medical Education thiab Tshawb Fawb; c1998–2019. Monoclonal gammopathy ntawm qhov tseem ceeb tsis paub qhov tseeb (MGUS): Cov tsos mob thiab ua rau; 2019 Tsib Hlis 21; [hais tawm 2019 Dec 21]; [txog 3 ntxaij]. Muaj los ntawm: https://www.mayoclinic.org/diseases-conditions/mgus/sym រោគសញ្ញា-causes/syc-20352362
7. Mayo Clinic: Mayo Medical Laboratories [Is Taws Nem]. Mayo Foundation for Medical Education thiab Tshawb Fawb; c1995–2019. Daim Ntawv Kuaj ID: FLCP: Immunoglobulin Dawb Lub Teeb Dawb, Ntshav: Lub Chaw Kho Mob thiab Kev Txhais Lus; [hais tawm 2019 Dec 21; [txog 4 ntxaij]. Muaj los ntawm: https://www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/84190
8. National Cancer Institute [Internet]. Bethesda (MD): Asmeskas Lub Tsev Haujlwm Saib Xyuas Kev Noj Qab Haus Huv thiab Tib Neeg Kev Ntshav Cell Neoplasms (suav nrog Ntau Tus Mob Hlwb Ntiag) Kev Kho Mob (PDQ®) –Txoj Cai Kho Mob; [kho tshiab 2019 Nov 8; hais tawm 2019 Dec 21]; [txog 3 ntxaij]. Muaj los ntawm: https://www.cancer.gov/types/myeloma/patient/myeloma-treatment-pdq
9. Teb Chaws Lub Plawv, Lub Ntsws, thiab Koom Haum Ntshav [Internet]. Bethesda (MD): Asmeskas Lub Chaw Haujlwm Saib Xyuas Kev Noj Qab Haus Huv thiab Tib Neeg; Kuaj ntshav; [hais tawm 2019 Dec 21]; [txog 3 ntxaij]. Muaj los ntawm: https://www.nhlbi.nih.gov/health-topics/blood-tests
10. University of Rochester Medical Center [Internet]. Rochester (NY): Tsev kawm qib siab Rochester Medical Center; c2019. Kev Qhia Txog Kev Noj Qab Haus Huv: Kev Taug Zog Dawb (Ntshav); [hais tawm 2019 Dec 21]; [txog 2 ntxaij]. Muaj los ntawm: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=serum_free_light_chains

Cov ntaub ntawv ntawm lub xaib no yuav tsum tsis txhob siv los hloov chaw kho mob lossis tswv yim kho mob. Hu rau kws kho mob yog tias koj muaj lus nug txog koj txoj kev noj qab haus huv.