Sclerosing cholangitis: nws yog dab tsi, cov tsos mob thiab kev kho mob

Zoo Siab

• Cov tsos mob ntawm sclerosing cholangitis
• Cov tseem ceeb ua
• Yuav kuaj li cas
• Txoj kev kho rau cholangitis sclerosing

Sclerosing cholangitis yog ib yam mob uas tsis tshua muaj tshwm sim rau cov txiv neej los ntawm kev koom nrog daim siab vim yog mob o thiab mob ua rau nqaim ntawm cov kwj dej uas hla cov kua tsib, uas yog qhov tseem ceeb rau txoj kev zom zaub mov, uas tuaj yeem ua, qee qhov xwm txheej, cov tsos mob ntawm qee qhov tsos mob, xws li ntau dhau, nkees daj, tawv nqaij daj thiab qhov muag thiab cov leeg tsis muaj zog.

Cov ua rau mob cholangitis yog tseem tsis tau pom meej heev, txawm li cas los xij ntseeg tias nws yuav cuam tshuam nrog cov phom sij autoimmune uas tuaj yeem ua rau muaj kev muaj mob zuj zus tuaj ntawm cov kab mob plab. Raws li keeb kwm, sclerosing cholangitis tuaj yeem faib ua ob hom loj:

• Thawj sclerosing cholangitis, nyob hauv qhov kev hloov pauv tau pib hauv cov kua tsib;
• Secondary sclerosing cholangitis, nyob rau hauv qhov kev hloov pauv yog qhov kev rau txim rau lwm qhov kev hloov pauv, xws li lub qog lossis tus menyuam mus rau ntawm qhov chaw, piv txwv.

Nws yog ib qho tseem ceeb tias keeb kwm ntawm cholangitis raug txheeb xyuas kom thiaj li kho tau zoo tshaj plaws tuaj yeem qhia tau, thiab yog li, nws raug nquahu kom mus sab laj tus kws kho mob lossis kws kho mob txhawm rau txhawm rau txhawm rau qhia kev ntsuas thiab ntsuas kev kuaj mob uas tso cai rau kev kuaj mob.

Cov tsos mob ntawm sclerosing cholangitis

Feem ntau ntawm cov cholangitis tsis ua rau pom cov tsos mob lossis cov tsos mob, thiab qhov kev hloov pauv no tsuas pom tshwm sim thaum cov duab ntsuas. Txawm li cas los xij, qee tus neeg yuav muaj cov tsos mob tshwm sim, tshwj xeeb tshaj yog thaum nws los txog sclerosing cholangitis, qhov twg muaj kev txhim kho bile rau hauv lub siab. Yog li, cov tsos mob tseem ceeb uas qhia tau tias muaj cholangitis yog:

• Nkees dhau heev;
• Khaus lub cev;
• Daim tawv daj thiab qhov muag;
• Tej zaum yuav ua daus no ua npaws thiab mob plab;
• Mob leeg tsis muaj zog;
• Poob phaus;
• Daim siab ua kom lub siab;
• Txhawb nqa spleen;
• Kev rov qab xanthomas, uas yog qhov txhab ntawm daim tawv nqaij ua los ntawm cov rog;
• Khaus.

Muaj qee kis, nws tseem tuaj yeem ua zawv plab, mob plab thiab muaj ntshav lossis hnoos qeev nyob hauv cov quav. Thaum muaj cov tsos mob no, tshwj xeeb yog tias lawv rov qab ua dua tas li los sis tas li, nws yog ib qho tseem ceeb kom sab laj nrog tus kws kho mob lossis kws kho mob txhawm rau kom kuaj tau thiab ua tiav kev kho mob tuaj yeem pib.

Cov tseem ceeb ua

Qhov ua rau mob sclerosing cholangitis tseem tsis tau tsim tsa zoo, txawm li cas los xij ntseeg tias nws yuav yog vim muaj qhov hloov kho autoimmune lossis cuam tshuam nrog caj ces caj ces lossis kis tau los ntawm kab mob lossis kab mob.

Tsis tas li ntawd, nws tseem ntseeg tias sclerosing cholangitis muaj feem xyuam rau kev mob ncauj plab, nyob rau hauv cov neeg mob hom mob hnyuv muaj feem yuav muaj kev pheej hmoo mob cholangitis.

Yuav kuaj li cas

Kev kuaj mob ntawm sclerosing cholangitis yog tsim los ntawm cov kws kho mob feem ntau lossis tus kws kho mob hauv chaw soj ntsuam los ntawm kev kuaj thiab ntsuas duab. Feem ntau, kev pib kuaj mob yog tsim los ntawm cov txiaj ntsig ntawm kev ntsuam xyuas uas ntsuas lub siab ua haujlwm, nrog kev hloov pauv ntawm daim siab tso tawm hauv lub siab, xws li TGO thiab TGP, ntxiv rau qhov nce ntawm alkaline phosphatase thiab gamma-GT. Qee qhov xwm txheej, tus kws kho mob kuj tuaj yeem thov cov kev ua kom muaj protein electrophoresis, uas cov theem ntawm gamma globulins ntau dua, feem ntau yog IgG, tuaj yeem pom.

Txhawm rau kom paub tseeb tias kev kuaj mob, tus kws kho mob tuaj yeem thov lub siab ua haujlwm thiab cholangiography, uas yog kev kuaj mob uas yog lub hom phiaj los soj ntsuam cov kua tsib lub plab thiab tshawb txoj kev los ntawm cov kua tsib los ntawm daim siab los ntawm daim siab mus rau duodenum, ua tau kom pom qhov hloov pauv. Nkag siab li cas cholangiography ua tiav.

Txoj kev kho rau cholangitis sclerosing

Kev kho mob rau sclerosing cholangitis tau ua tiav raws li qhov mob ntawm cholangitis thiab lub hom phiaj los txhawb cov kev mob tshwm sim thiab tiv thaiv kom tsis txhob muaj teeb meem. Nws yog ib qho tseem ceeb tias kev kho mob tau pib sai tom qab kuaj pom kev tiv thaiv kab mob kev tiv thaiv thiab ua rau muaj teeb meem xws li mob siab, mob ntshav siab thiab mob siab.

Yog li, kev siv cov tshuaj uas muaj cov tshuaj ursodeoxycholic acid, cov lag luam hu ua Ursacol, tej zaum yuav qhia los ntawm tus kws kho mob, ntxiv rau kev kho mob endoscopic kom txo qis ntawm kev cuam tshuam thiab nyiam tso cai ntawm cov kua tsib. Hauv feem ntau ntawm cov mob cholangitis, uas tsis muaj kev txhim kho hauv cov tsos mob nrog kev siv tshuaj, lossis thaum cov tsos mob tshwm sim, tus kws kho mob tuaj yeem pom zoo ua lub siab hloov pauv.