Ivosidenib

Zoo Siab

• Ua ntej noj ivosidenib,
• Ivosidenib tuaj yeem tsim kev mob tshwm sim. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:
• Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no lossis cov uas teev rau hauv seem ceeb toom ceeb toom, hu rau koj tus kws kho mob tam sim ntawd lossis tau txais kev kho mob kub ceev:

Ivosidenib tuaj yeem ua rau mob hnyav lossis tuag taus ntawm cov tsos mob hu ua kev sib txawv ntawm tus mob. Koj tus kws kho mob yuav saib xyuas koj kom zoo zoo seb koj puas tsim tus mob no. Yog koj pom muaj cov tsos mob li hais hauv qab no, hu rau koj tus kws kho mob tam sim ntawd: ua npaws, hnoos, tawm pob, nce lub cev sai sai, tso zis tsawg, o caj npab lossis txhais ceg, kiv taub hau lossis mob taub hau, ua pa luv, lossis ua pa nyuaj. Cov tsos mob no yuav tshwm sim txog li 3 hlis tom qab pib kho nrog ivosidenib. Ntawm thawj lub cim qhia tias koj tab tom tsim kho tus mob txawv txav, koj tus kws kho mob yuav sau ntawv noj tshuaj los kho tus mob, thiab yuav qhia koj kom tsis txhob noj tshuaj ivosidenib rau qee lub sijhawm.

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob yuav xaj qee yam kev kuaj mob ua ntej thiab thaum kho koj tus kws kho mob kuaj seb koj lub cev teb li cas rau ivosidenib.

Koj tus kws kho mob lossis kws muag tshuaj yuav muab daim ntawv qhia txog cov neeg mob rau koj (Siv Tshuaj Kho Mob) thaum koj pib kho mob ivosidenib thiab txhua zaus koj rov ntim tshuaj. Nyeem cov ntaub ntawv kom zoo thiab nug koj tus kws kho mob lossis kws muag tshuaj yog tias koj muaj lus nug. Koj kuj tuaj yeem mus saib zaub mov thiab Tshuaj (FDA) lub vev xaib (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kom tau Phau Ntawv Qhia Tshuaj.

Ivosidenib yog siv los kho qee yam mob myeloid leukemia (AML; ib hom mob cancer uas pib hauv cov qe ntshav dawb) uas tau rov qab los lossis uas tsis tau zoo dua tom qab cov kev kho mob dhau los. Ivosidenib tseem tseem siv coj los kho qee hom mob AML hauv qee cov neeg laus hnub nyoog laus dua 75 xyoo yog thawj qhov kev kho mob. Ivosidenib nyob hauv ib chav ntawm cov tshuaj cad IDH1 inhibitors. Nws ua haujlwm los ntawm kev ua kom qeeb los yog txwv tsis pub muaj kev mob nce hlwb.

Ivosidenib los ua ib ntsiav tshuaj los noj ntawm qhov ncauj. Feem ntau nws noj nrog lossis tsis noj ib zaug ib hnub. Ua tsis tau noj nws nrog zaub mov muaj roj ntau (zoo li cov khoom kib thiab cov khoom noj ceev). Siv ivosidenib nyob ib ncig ntawm tib lub sijhawm txhua hnub. Ua raws li cov lus qhia ntawm koj daim ntawv sau tshuaj noj kom zoo, thiab nug koj tus kws kho mob lossis kws muag tshuaj kom piav qhia ib feem uas koj tsis nkag siab. Noj ivosidenib raws nraim li qhia. Tsis txhob noj ntau dua lossis tsawg dua lossis siv ntau dua li uas koj tus kws khomob tau qhia.

Nqos cov ntsiav tshuaj tag nrho; tsis txhob sib faib, zom, lossis tsoo lawv.

Yog tias koj ntuav tom qab noj ivosidenib, tsis txhob noj ib qho tshuaj ntxiv. Ua koj cov tshuaj noj tas li.

Koj tus kws kho mob tuaj yeem txo koj cov koob tshuaj lossis ib ntus lossis txiav tawm koj txoj kev kho mob nrog ivosidenib nyob ntawm koj qhov lus teb rau kev kho lossis ib qho kev mob tshwm sim uas koj muaj. Tham nrog koj tus kws kho mob txog saib koj xav li cas thaum kho koj tus mob.

Nug koj tus kws muag tshuaj lossis tus kws kho mob txog cov ntawv luam ntawm cov ntaub ntawv tsim tawm rau tus neeg mob.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej noj ivosidenib,

• qhia rau koj tus kws kho mob thiab tus kws muag tshuaj yog tias koj muaj kev fab tshuaj rau ivosidenib, lwm yam tshuaj noj, lossis lwm yam tshuaj hauv ivosidenib ntsiav tshuaj. Nug koj tus kws muag tshuaj lossis tshawb xyuas Phau Ntawv Qhia Tshuaj Kho Mob rau cov npe ntawm cov khoom siv.
• qhia rau koj tus kws kho mob thiab kws muag tshuaj tias lwm yam tshuaj uas tsis yog kws kho mob thiab cov tshuaj uas tsis yog kws kho mob sau, tshuaj vitamins, khoom noj khoom haus zoo, thiab tshuaj ntsuab koj tau noj lossis npaj yuav noj. Nco ntsoov hais txog qee yam ntawm cov hauv qab no: amiodarone (Nexterone, Pacerone), carbamazepine (Equetro, Tegretol, Teril, lwm tus), clarithromycin, diltiazem (Cardizem, Cartia, Diltzac, Tiazac, lwm tus), efavirenz (Sustiva, hauv Atripla, hauv Symfi), erythromycin (Eryc), fluconazole (Diflucan), indinavir (Crixivan), itraconazole (Onmel, Sporanox, Tolsura), ketoconazole, qhov ncauj tiv thaiv tsis muaj qhov zoo xws li qee yam ('tshuaj txwv yug me nyuam'), thaj ua rau thaj chaw mos, thiab thaj chaw muaj tshuaj hormonal vaginal, nefazodone , nelfinavir (Viracept), nevirapine (Viramune), phenobarbital, phenytoin (Dilantin, Phenytek), pioglitazone (Actos), procainamide, quinidine (hauv Nuedexta), rifabutin (Mycobutin), rifampin (Rifadon, Rifavin, Rifadon, Rifavin, Rifavin, Rifavin, Rifavin, Rifavin, Rifavin, Rifater (Norvir, hauv Kaletra, hauv Viekira), saquinavir (Fortovase, Invirase), telithromycin (Ketek), thiab verapamil (Calan, Verelan, hauv Tarka). Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv. Ntau lwm yam tshuaj yuav tuaj yeem cuam tshuam nrog ivosidenib, yog li nco ntsoov qhia koj tus kws kho mob txog txhua yam tshuaj uas koj noj, txawm tias tsis tshwm nyob hauv daim ntawv no.
• qhia koj tus kws kho mob tias yam tshuaj ntsuab koj noj, tshwj xeeb tshaj yog St. John's Wort.
• qhia rau koj tus kws kho mob yog tias koj lossis ib tus neeg hauv koj tsev neeg muaj lossis puas tau muaj sijhawm QT ntev (mob uas ua rau muaj kev pheej hmoo mob plawv tsis zoo uas yuav ua rau tsaus muag lossis cia li tuag kiag); yog tias koj muaj lossis ib txwm muaj lub plawv dhia qeeb lossis lub plawv tsis xwm yeem lossis lwm tus mob plawv; cov ntshav ntshav qis ntawm sodium, potassium, lossis magnesium; cov teeb meem hlab ntsha hlwb; mob rau daim siab, nrog rau mob ntsws; lossis yog tias koj tab tom tau txais kev kho lim ntshav lossis yog tias koj muaj lossis puas tau muaj mob raum.
• qhia koj tus kws kho mob yog tias koj cev xeeb tub los yog npaj yuav cev xeeb tub, lossis pub mis niam. Koj yuav tsum paub tias ivosidenib tuaj yeem txo qhov kev ua haujlwm zoo tshaj plaws ntawm kev sib deev hormonal (tshuaj txwv, tshuaj pleev ib ce, nplhaib lossis txhaj tshuaj) thaum koj noj cov tshuaj no. Tham nrog koj tus kws kho mob txog kev siv lwm txoj kev tswj tsis pub muaj menyuam. Yog tias koj cev xeeb tub thaum noj cov tshuaj ivosidenib, hu rau koj tus kws kho mob tam sim ntawd. Ivosidenib tuaj yeem tsim kev mob rau menyuam hauv plab.
• qhia rau koj tus kws kho mob yog tias pub mis niam rau menyuam. Tsis txhob noj mis thaum koj kho nrog ivosidenib thiab rau 1 hlis tom qab koj koob zaum kawg.

Tham nrog koj tus kws kho mob txog kev noj txiv kab ntxwv qaub thiab haus kua txiv thaum lub sijhawm noj cov tshuaj no.

Nco ntsoov tias koj haus dej kom ntau lossis lwm yam dej txhua hnub thaum koj tab tom noj ivosidenib.

Yog tias koj cov tshuaj ntxiv tom qab 12 teev lossis tshaj saud, noj cov koob tshuaj uas ploj lawm thaum koj nco qab. Txawm li cas los xij, yog tias qhov koob tshuaj ntxiv yuav raug noj tsawg dua 12 teev, hla cov koob tshuaj uas tsis nco qab thiab txuas ntxiv rau koj lub sijhawm noj tshuaj kom tsis tu ncua. Tsis txhob noj tshuaj rau ob zaug kom ua rau qhov ploj lawm ib zaug.

Ivosidenib tuaj yeem tsim kev mob tshwm sim. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

• mob taub hau
• nkees
• mob pob qij txha lossis mob leeg
• zawv plab
• cem quav
• ntuav
• xeev siab
• tsis qab los noj mov
• qhov ncauj mob thiab mob txhab
• mob plab

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no lossis cov uas teev rau hauv seem ceeb toom ceeb toom, hu rau koj tus kws kho mob tam sim ntawd lossis tau txais kev kho mob kub ceev:

• kiv kiv, kiv taub hau, lossis tsaus muag
• qhov tsis muaj zog lossis caj dab hnov ​​hauv cov ceg, caj npab, lossis lub cev sab saud; loog thiab mob ntawm ib sab lossis ob sab ntawm lub cev; hloov pauv ntawm koj lub peev xwm kom pom, kov, hnov, lossis saj; kev hnov ​​lossis hlawv cov roj prickling; lossis ua pa nyuaj
• mob hauv siab

Ivosidenib tuaj yeem ua lwm cov kev mob tshwm sim. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum noj cov tshuaj no.

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).

Khaws cov tshuaj no rau hauv lub khob uas nws nkag los, kaw kom nruj, thiab ncav tsis cuag ntawm cov menyuam. Khaws nws ntawm chav sov thiab deb ntawm qhov kub thiab noo noo (tsis nyob hauv chav dej).

Nws yog ib qho tseem ceeb kom tsis txhob muaj txhua yam tshuaj rau qhov tsis pom thiab ncav cuag ntawm cov menyuam yaus ntau li ntau ntim (xws li tshuaj ntsiav tshuaj txhua lub limtiam thiab cov tshuaj rau qhov muag, tshuaj pleev, pleev xim, thiab nqus tshuaj) tsis tiv thaiv menyuam yaus thiab cov menyuam yaus tuaj yeem qhib lawv tau yooj yim. Txhawm rau tiv thaiv cov menyuam yaus me los ntawm kev lom, ib txwm kaw lub kaus mom kev nyab xeeb thiab muab cov tshuaj tso rau qhov chaw nyab xeeb - ib qho chaw nyob thiab deb thiab tawm ntawm lawv pom thiab ncav cuag. http://www.upandaway.org

Cov tshuaj tsis siv tshuaj yuav tsum tau muab pov tseg hauv txoj kev tshwj xeeb kom ntseeg tau tias cov tsiaj, menyuam yaus, thiab lwm tus neeg tsis tuaj yeem haus lawv. Txawm li cas los xij, koj yuav tsum tsis txhob yaug cov tshuaj no hauv lub qhov viv. Hloov chaw, txoj hauv kev zoo tshaj plaws hauv kev muab koj cov tshuaj tshem tawm yog los ntawm kev siv tshuaj rov qab. Tham nrog koj tus kws muag tshuaj lossis tiv tauj koj lub chaw khaws khib nyiab / chaw khaws khoom ubno hauv ib cheeb tsam kom paub txog cov haujlwm thim rov qab hauv koj lub zej zog. Saib ntawm FDA's Kev Nyab Xeeb Kev Nyab Xeeb Kev Siv Tshuaj lub vev xaib (http://goo.gl/c4Rm4p) kom paub cov ntaub ntawv ntau ntxiv yog tias koj tsis muaj kev nkag mus saib rov qab.

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Koj tus kws kho mob yuav xaj kuaj sim ua ntej koj pib kev kho mob seb koj puas tuaj yeem kho tus mob cancer ivosidenib.

Tsis txhob cia lwm tus noj koj cov tshuaj. Nug koj tus kws muag tshuaj cov lus nug uas koj muaj txog kev rov ntxiv tshuaj rau koj.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

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