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Teriflunomide Shows Benefits in Longterm Care of Multiple Sclerosis
Daim Duab: Teriflunomide Shows Benefits in Longterm Care of Multiple Sclerosis

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Teriflunomide tuaj yeem ua rau lub siab mob hnyav lossis ua rau muaj sia tuag, uas yuav xav tau lub siab hloov ntshav. Txoj kev pheej hmoo ntawm daim siab yuav raug nce ntxiv hauv cov neeg noj lwm yam tshuaj uas paub ua rau lub siab puas, thiab hauv cov neeg uas twb muaj kab mob siab. Qhia koj tus kws kho mob yog tias koj muaj kab mob siab. Koj tus kws kho mob yuav hais kom koj tsis txhob noj cov tshuaj teriflunomide. Qhia rau koj tus kws kho mob thiab kws muag tshuaj txog txhua yam tshuaj uas koj siv yog li lawv tuaj yeem tshawb xyuas seb ib qho ntawm koj cov tshuaj puas tuaj yeem ua rau muaj kev pheej hmoo ntxiv uas koj yuav ua mob rau daim siab thaum kho koj nrog teriflunomide. Yog koj muaj cov tsos mob li hais no, hu rau koj tus kws kho mob tam sim ntawd: xeev ntuav, ntuav, nkees heev, ntshav txawv los yog doog, tsis muaj zog, tsis qab los noj mov, mob rau sab xis sab sauv ntawm lub plab, qw nqaij tawv lossis muag , tso zis tsaus nti, lossis tsos mob zoo li ua npaws. Yog tias xav paub txog daim siab puas, koj tus kws kho mob tuaj yeem nres teriflunomide thiab yuav muab kev kho mob rau koj uas yuav pab tshem tawm cov teriflunomide sai dua ntawm koj lub cev.


Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob yuav xaj qee yam kev kuaj mob ua ntej koj pib kho thiab tsis tu ncua thaum lub sijhawm kho koj lub cev kom kuaj xyuas koj lub cev cov lus teb rau teriflunomide.

Tsis txhob noj tshuaj teriflunomide yog tias koj xeeb tub lossis npaj yuav muaj menyuam. Teriflunomide tuaj yeem tsim kev puas tsuaj rau tus me nyuam hauv plab. Koj yuav tsum tsis txhob pib noj cov tshuaj teriflunomide kom txog rau thaum koj tau kuaj cev xeeb tub nrog qhov tshwm sim tsis zoo thiab koj tus kws kho mob qhia koj tias koj tsis tau xeeb tub. Koj yuav tsum siv txoj hauv kev tswj kom tsis txhob muaj menyuam ua ntej koj pib noj cov tshuaj teriflunomide, thaum siv tshuaj teriflunomide, thiab ntev txog 2 xyoos tom qab kho, txog thaum kuaj ntshav pom tias koj muaj tsawg theem ntawm teriflunomide hauv koj cov ntshav. Yog tias koj lub sijhawm lig, koj tsis ncua sijhawm, lossis koj xav tias koj cev xeeb tub thaum kho nrog teriflunomide lossis rau 2 xyoo tom qab koj kho, hu rau koj tus kws kho mob tam sim ntawd. Yog tias koj yog txiv neej thiab koj tus khub tuaj yeem cev xeeb tub, koj thiab koj tus khub yuav tsum siv kev tswj tsis pub muaj menyuam thaum lub sijhawm kho. Yog tias koj lossis koj tus khub npaj yuav ua kom cev xeeb tub lossis cev xeeb tub, tham nrog koj tus kws kho mob txog kev kho mob uas yuav pab tshem tawm teriflunomide sai dua hauv koj lub cev tom qab koj tsum tsis noj tshuaj.


Koj tus kws kho mob lossis kws muag tshuaj yuav muab daim ntawv qhia txog cov neeg mob rau koj (Siv Tshuaj Kho Mob) thaum koj pib kho nrog teriflunomide thiab txhua zaus koj rov ntim tshuaj. Nyeem cov ntaub ntawv kom zoo thiab nug koj tus kws kho mob lossis kws muag tshuaj yog tias koj muaj lus nug. Koj kuj tuaj yeem mus saib tau Chaw Tswj Xyuas Khoom Noj thiab Tshuaj (FDA) lub vev xaib (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) lossis cov chaw tsim tshuaj paus lub vev xaib kom tau txais Kev Qhia Tshuaj.

Tham nrog koj tus kws kho mob txog cov kev pheej hmoo ntawm kev noj tshuaj teriflunomide.

Teriflunomide yog siv los kho cov neeg laus nrog ntau hom mob sclerosis (MS; ib tug kabmob uas cov hlab ntsha tsis ua haujlwm zoo thiab tib neeg yuav muaj qhov tsis muaj zog, ua tsis taus pa, tsis tuaj yeem ua haujlwm rau cov leeg, thiab muaj teeb meem ntawm lub zeem muag, hais lus thiab zais zis). :

  • cov chaw khomob raug cais (CIS; cov tsos mob hauv lub cev uas ntev li 24 teev),
  • foos rov ua daim ntawv dua (hom mob uas cov tsos mob tshwm sim ib lub sijhawm), lossis
  • theem ob hom foos (hom mob uas tus mob huam tuaj feem ntau).

Teriflunomide yog nyob rau hauv chav kawm ntawm cov tshuaj hu ua immunomodulatory tus neeg sawv cev. Nws tau xav tias ua haujlwm los ntawm kev txo qis o thiab txo qis kev ua haujlwm ntawm cov kabmob tiv thaiv kabmob uas yuav ua rau lub hlwb tsis zoo.


Teriflunomide los ua ib ntsiav tshuaj noj ntawm qhov ncauj. Nws feem ntau yog noj ib zaug ib hnub nrog lossis tsis muaj zaub mov. Siv tshuaj teriflunomide nyob rau tib lub sijhawm txhua hnub. Ua raws li cov lus qhia ntawm koj daim ntawv sau tshuaj noj kom zoo, thiab nug koj tus kws kho mob lossis kws muag tshuaj kom piav qhia ib feem uas koj tsis nkag siab. Noj teriflunomide raws nraim li qhia. Tsis txhob noj ntau dua lossis tsawg dua lossis siv ntau dua li uas koj tus kws khomob tau qhia.

Teriflunomide tuaj yeem pab tswj cov tsos mob ntawm ntau tus mob sclerosis, tab sis tsis kho nws. Txuas ntxiv noj cov tshuaj teriflunomide txawm hais tias koj xis neej. Tsis txhob tsum tsis txhob noj tshuaj teriflunomide yam tsis tau tham nrog koj tus kws kho mob.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej noj cov tshuaj teriflunomide,

  • qhia rau koj tus kws kho mob thiab tus kws muag tshuaj yog tias koj ua xua nrog teriflunomide (ua pob ua xua, khaus khaus, ua pa luv, txhaws ntsej muag, qhov muag, qhov ncauj, caj pas, nplaig, daim di ncauj, tes, ko taw, pob taws, lossis qis ceg), leflunomide (Arava) , lwm yam tshuaj, lossis ib qho ntawm cov khoom xyaw hauv cov ntsiav tshuaj teriflunomide. Nug koj tus kws muag tshuaj lossis tshawb xyuas Phau Ntawv Qhia Tshuaj Kho Mob rau cov npe ntawm cov khoom siv.
  • qhia rau koj tus kws kho mob yog tias koj noj tshuaj leflunomide (Arava). Koj tus kws kho mob yuav qhia koj kom tsis txhob noj tshuaj teriflunomide yog tias koj noj tshuaj no.
  • qhia rau koj tus kws kho mob thiab kws muag tshuaj tias lwm yam tshuaj uas tsis yog kws kho mob thiab cov tshuaj uas tsis yog kws kho mob sau, tshuaj vitamins, khoom noj khoom haus zoo, thiab tshuaj ntsuab koj tau noj lossis npaj yuav noj. Nco ntsoov hais txog cov tshuaj teev tseg rau hauv seem ceebtoom CEEB TOOM thiab ib qho twg ntawm cov hauv qab no: alosetron (Lotronex); anticoagulants ('ntshav thinners') xws li warfarin (Coumadin, Jantoven); atorvastatin (Lipitor, hauv Caduet); cefaclor; cimetidine (Tagamet); ciprofloxacin (Cipro); duloxetine (Cymbalta); eltrombopag (Promacta); furosemide (Lasix); gefitinib (Iressa); ketoprofen; cov tshuaj uas tuaj yeem ua rau cov hlab ntsha puas tsuaj xws li tshuaj rau mob cancer, HIV, lossis AIDS; lwm cov tshuaj uas ua rau lub cev tiv thaiv tsis muaj zog xws li azathioprine (Azasan, Imuran), cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), thiab tacrolimus (Astagraf, Envarsus XR, Prograf); methotrexate (Otrexup, Rasuvo, Trexall); mitoxantrone; cais pawg (Starlix); qhov ncauj tiv thaiv tsis tau noj (tshuaj txwv); paclitaxel (Abraxane, Taxol); penicillin G; pioglitazone (Actos, hauv Actoplus Met, hauv Duetact); pravastatin (Pravachol); repaglinide (Prandin, hauv Prandimet); phom phom (Rifadin, Rimactane, hauv Rifamate, hauv Rifater); rosiglitazone (Avandia); rosuvastatin (Crestor); simvastatin (Zocor, hauv Vytorin); theophylline (Elixophyllin, Theo-24, Uniphyl, lwm tus); tizanidine (Zanaflex); thiab zidovudine (Retrovir, hauv Combivir, hauv Trizivir). Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv. Ntau lwm yam tshuaj kuj tseem tuaj yeem cuam tshuam nrog teriflunomide, yog li nco ntsoov qhia koj tus kws kho mob txog txhua yam tshuaj uas koj siv, txawm tias tsis tshwm nyob hauv daim ntawv no.
  • qhia rau koj tus kws kho mob yog tias koj muaj mob tam sim no, suav nrog kev kis tus kab mob txuas ntxiv uas tsis ploj, lossis yog koj muaj lossis muaj kev tawm tsam tawv nqaij tom qab koj siv lwm yam tshuaj; ntshav qab zib; teeb meem ua pa; mob qog lossis lwm yam mob cuam tshuam rau cov pob txha pob txha los yog kev tiv thaiv kab mob hauv lub cev; ntshav siab; mob peripheral neuropathy (loog, hlawv lossis tingling hauv tes lossis taw uas txawv ntawm koj cov tsos mob MS); lossis mob raum.
  • qhia rau koj tus kws kho mob yog tias koj pub mis. Tsis txhob noj mis thaum noj cov tshuaj teriflunomide.
  • yog tias koj tus khub npaj yuav cev xeeb tub, koj yuav tsum tham nrog koj tus kws kho mob txog kev tso tseg cov tshuaj teriflunomide thiab txais kev kho mob kom pab tshem tawm cov tshuaj no ntawm koj lub cev sai dua. Yog tias koj tus khub tsis npaj yuav los cev xeeb tub, koj thiab koj tus khub yuav tsum siv txoj kev tswj kom tsis txhob muaj menyuam thaum lub sijhawm kho nrog teriflunomide thiab mus txog 2 xyoos tom qab kho, kom txog rau thaum kuaj ntshav pom tias koj muaj qis tsawg ntawm teriflunomide hauv koj ntshav.
  • yog tias koj muaj kev phais, suav nrog kev phais hniav, qhia tus kws kho mob lossis kws kho hniav uas koj noj teriflunomide.
  • tej zaum koj yuav tau kis tus kab mob ntsws (TB; mob ntsws hnyav) tab sis tsis muaj tsos mob dab tsi. Qhia koj tus kws kho mob yog tias koj tau lossis muaj ib txwm muaj mob TB, yog tias koj tau nyob lossis mus xyuas lub tebchaws uas muaj tus kabmob TB, lossis koj tau nyob nrog ib tus neeg uas muaj lossis muaj tus kabmob TB. Ua ntej koj pib kev kho mob nrog teriflunomide, koj tus kws kho mob yuav kuaj daim tawv nqaij seb koj puas muaj TB. Yog tias koj muaj TB, koj tus kws kho mob yuav kho tus kab mob no ua ntej koj pib noj cov tshuaj teriflunomide.
  • tsis muaj kev txhaj tshuaj yam tsis tau tham nrog koj tus kws kho mob thaum koj noj teriflunomide thiab rau 6 lub hlis tom qab koj tsum tsis noj tshuaj.
  • koj yuav tsum paub tias teriflunomide tuaj yeem ua rau ntshav siab. Koj yuav tsum tau kuaj xyuas koj cov ntshav siab ua ntej pib kho thiab ua ntu zus thaum koj noj cov tshuaj no.

Tshwj tsis yog koj tus kws kho mob hais rau koj lwm yam, txuas ntxiv koj li kev noj haus zoo.

Noj cov koob tshuaj uas ploj lawm sai li sai tau thaum koj nco qab nws. Txawm li cas los xij, yog tias nws yuav luag txog rau koob tshuaj txuas ntxiv, hla cov koob tshuaj uas tsis nco qab noj thiab txuas ntxiv koj lub sijhawm noj tshuaj kom tsis tu ncua. Tsis txhob noj tshuaj rau ob zaug kom ua rau qhov ploj lawm ib zaug.

Teriflunomide yuav ua rau muaj kev phiv tshuaj. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

  • plaub hau poob
  • zawv plab
  • qhov muag plooj
  • mob hniav
  • pob txuv
  • mob pob qij txha lossis mob leeg
  • ntxhov siab
  • poob phaus

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no lossis cov uas teev rau hauv seem ceeb toom ceeb toom, tsum tsis txhob noj cov tshuaj teriflunomide thiab hu rau koj tus kws kho mob tam sim ntawd lossis tau txais kev kho mob kub ceev:

  • ceev, tsis meej, lossis qeeb plawv dhia
  • mob taub hau
  • kiv taub hau
  • daj ntseg tawv nqaij
  • tsis meej pem
  • kub taub hau, hnoos, mob caj pas, ua daus no, thiab lwm yam cim ntawm tus kab mob
  • loog, mob, lossis tingling hauv tes, caj npab, txhais ceg, lossis ceg
  • poob ntawm cov leeg khi tawm
  • tsis muaj zog lossis hnyav nyob hauv ceg
  • tawv nqaij, grey
  • liab, tev lossis tawv nqaij ntawm qhov tawv nqaij
  • ua pob
  • khaus
  • khaus
  • teeb meem nqos
  • o ntawm lub ntsej muag, qhov muag, qhov ncauj, caj pas, nplaig, lossis daim di ncauj
  • txog siav
  • xoo pob tuaj yeem uas kub cev, ua qog o, lossis o ntawm lub ntsej muag
  • mob plab, sab, lossis mob nraub qaum

Teriflunomide tuaj yeem ua rau lwm cov kev mob tshwm sim. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum noj cov tshuaj no.

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).

Khaws cov tshuaj no rau hauv lub khob uas nws nkag los, kaw kom nruj, thiab ncav tsis cuag ntawm cov menyuam. Khaws nws ntawm chav sov thiab deb ntawm qhov kub thiab noo noo (tsis nyob hauv chav dej).

Nws yog ib qho tseem ceeb kom tsis txhob muaj txhua yam tshuaj rau qhov tsis pom thiab ncav cuag ntawm cov menyuam yaus ntau li ntau ntim (xws li tshuaj ntsiav tshuaj txhua lub limtiam thiab cov tshuaj rau qhov muag, tshuaj pleev, pleev xim, thiab nqus tshuaj) tsis tiv thaiv menyuam yaus thiab cov menyuam yaus tuaj yeem qhib lawv tau yooj yim. Txhawm rau tiv thaiv cov menyuam yaus me los ntawm kev lom, ib txwm kaw lub kaus mom kev nyab xeeb thiab muab cov tshuaj tso rau qhov chaw nyab xeeb - ib qho chaw nyob thiab deb thiab tawm ntawm lawv pom thiab ncav cuag. http://www.upandaway.org

Cov tshuaj tsis siv tshuaj yuav tsum tau muab pov tseg hauv txoj kev tshwj xeeb kom ntseeg tau tias cov tsiaj, menyuam yaus, thiab lwm tus neeg tsis tuaj yeem haus lawv. Txawm li cas los xij, koj yuav tsum tsis txhob yaug cov tshuaj no hauv lub qhov viv. Hloov chaw, txoj hauv kev zoo tshaj plaws hauv kev muab koj cov tshuaj tshem tawm yog los ntawm kev siv tshuaj rov qab. Tham nrog koj tus kws muag tshuaj lossis tiv tauj koj lub chaw khaws khib nyiab / chaw khaws khoom ubno hauv ib cheeb tsam kom paub txog cov haujlwm thim rov qab hauv koj lub zej zog. Saib ntawm FDA's Kev Nyab Xeeb Kev Nyab Xeeb Kev Siv Tshuaj lub vev xaib (http://goo.gl/c4Rm4p) kom paub cov ntaub ntawv ntau ntxiv yog tias koj tsis muaj kev nkag mus saib rov qab.

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Tsis txhob cia lwm tus noj koj cov tshuaj. Nug koj tus kws muag tshuaj cov lus nug uas koj muaj txog kev rov ntxiv tshuaj rau koj.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

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