Ibritumomab Txhaj Tshuaj

Zoo Siab

• Ua ntej txhaj tshuaj ibritumomab,
• Ibritumomab txhaj tshuaj tuaj yeem ua rau phiv. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:
• Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog koj muaj cov tsos mob uas teev rau hauv seem ceeb toom ceeb toom los yog ib qho ntawm cov tsos mob hauv qab no, hu rau koj tus kws kho mob tam sim ntawd:
• Cov tsos mob ntawm kev noj haus ntau heev yuav suav nrog cov hauv qab no:

Ob peb teev ua ntej txhua koob ntawm ibritumomab txhaj, tshuaj uas hu ua rituximab (Rituxan) tau muab. Qee tus neeg mob tau ua rau muaj kev tsis haum lossis lub neej tsis haum thaum lawv tau txais rituximab lossis tsis ntev tom qab lawv tau txais rituximab. Cov kev tshwm sim no tau tshwm sim feem ntau nrog kev txhaj thawj rituximab. Qee cov neeg mob tau tuag hauv 24 teev tom qab tau txais rituximab. Qhia rau koj tus kws kho mob yog tias koj muaj kev fab tshuaj rau rituximab lossis cov tshuaj uas ua los ntawm cov murine (nas) cov protein, lossis yog koj tsis paub meej tias cov tshuaj uas koj fab rau yog ua los ntawm cov protein protein tua. Kuj qhia koj tus kws kho mob yog tias koj tau raug kho nrog cov tshuaj uas ua los ntawm cov protein ua haujlwm. Yog li, tej zaum koj yuav muaj kev tsis haum nrog rituximab. Koj tus kws kho mob yuav xaj kom kuaj seb koj puas muaj qhov ua xua nrog rituximab.

Koj tus kws kho mob yuav muab tshuaj rau koj ua ntej koj tau txais rituximab los pab tiv thaiv kev tawm tsam rituximab. Yog tias koj muaj qhov tshuaj tiv thaiv rau rituximab, koj tus kws kho mob yuav tsum tsis muab tshuaj rau koj rau lub sijhawm lossis tuaj yeem muab tshuaj rau koj qeeb dua. Yog tias qhov kev txhaum fab hnyav, koj tus kws kho mob yuav txiav rituximab infusion thiab yuav tsis txuas ntxiv kev kho mob nrog ibritumomab txhaj tshuaj. Qhia rau koj tus kws kho mob tam sim ntawd yog tias koj muaj cov kev mob tshwm sim hauv qab no lossis sai tom qab koj kho rituximab: hnoos; ua pa nyuaj lossis nqos; nruj ntawm lub caj pas; khaus; khaus; o ntawm lub qhov muag, ntsej muag, daim di ncauj, tus nplaig, qhov ncauj, lossis caj pas; mob hauv siab, puab tsaig, caj npab, nraub qaum, lossis caj dab; tsis meej pem; tsis nco qab; lub plawv dhia ceev; hws; daj ntseg tawv nqaij; cov pa ceev; tsis tso zis ntau ntxiv; los yog txias tes thiab taw.

Kev kho mob nrog rituximab thiab ibritumomab txhaj tshuaj yuav ua rau muaj kev cuam tshuam ntawm cov qe ntshav hauv koj lub cev ntau heev. Qhov kev txo qis no yuav tshwm sim 7 txog 9 lub lis piam tom qab kho koj tus mob thiab yuav nyob ntev li 12 lub lis piam lossis ntev dua. Qhov kev txo qis no yuav ua rau mob hnyav lossis tuag taus lossis ntshav khov. Koj tus kws kho mob yuav tsis muab tshuaj rau koj ibritumomab yog tias koj cov qe ntshav tau mob loj heev los ntawm mob cancer, yog tias koj hloov hlwb pob txha, yog tias koj tsis tuaj yeem tsim cov qia hlwb txaus (cov hlwb pom hauv pob txha pob txha uas tuaj yeem paub tab. ib hom qe ntshav twg) kom hloov hlwb pob txha, lossis yog koj twb muaj cov qe ntshav tsawg nyob hauv lawm. Qhia rau koj tus kws kho mob yog tias koj noj ib qho tshuaj hauv qab no: tshuaj anticoagulants ('ntshav nyias') xws li warfarin (Coumadin, Jantoven); cov tshuaj aspirin thiab lwm cov tshuaj tiv thaiv tsis haum (NSAIDs) xws li ibuprofen (Advil, Motrin) thiab naproxen (Aleve); thiab clopidogrel (Plavix). Yog tias koj muaj ib qho ntawm cov tsos mob hauv qab no, hu rau koj tus kws kho mob tam sim ntawd: tawv nqaij daj; tsis muaj zog; doog ntshav los ntshav; liab doog los sis thaj ua rau thaj nqaij tawv; dub lossis ntshav quav; ntuav yog ntshav lossis zoo li thaj chaw kas fes; zawv plab; lossis mob caj pas, ua npaws, ua daus no, hnoos, lossis lwm yam cim ntawm tus kabmob.

Kev kho mob nrog rituximab thiab ibritumomab txhaj tshuaj yuav ua rau muaj kev txhaum tawv nqaij lossis tuag taus. Cov kev phiv tshuaj no yuav tshwm sim sai li ob peb hnub tom qab kho lossis ntev li 4 lub hlis tom qab kho tas. Qhia rau koj tus kws kho mob tam sim ntawd yog tias koj tawm hlwv ntawm koj daim tawv lossis sab hauv ntawm koj lub qhov ncauj lossis qhov ntswg, tawm pob lossis tawv nqaij. Koj tus kws kho mob yuav tsis muab ibritumomab ntxiv rau koj yog tias koj muaj cov tsos mob no.

Tom qab koj tau txhaj thawj koob tshuaj ibritumomab, koj tus kws kho mob yuav xaj thaij duab thaij (kuaj uas pom ib daim duab ntawm tag nrho lossis ib feem ntawm sab hauv ntawm lub cev) saib seb cov tshuaj tau kis mus thoob koj lub cev li cas. Yog tias cov tshuaj tsis kis mus rau koj lub cev raws li qhov xav, koj yuav tsis tau txais koj ib koob tshuaj ibritumomab zaum thib ob.

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob yuav xaj qee yam kev kuaj mob thaum koj kho thiab ntev txog 3 lub hlis tom qab koj txoj kev kho mob kuaj koj lub cev teb rau ibritumomab txhaj.

Tham nrog koj tus kws kho mob txog cov kev pheej hmoo ntawm kev txhaj tshuaj ibritumomab.

Ibritumomab txhaj tshuaj yog siv nrog rituximab (Rituxan) los kho qee yam mob uas tsis yog Hodgkin's lymphoma (NHL; mob cancer uas pib hauv cov hlwb ntawm cov tshuaj tiv thaiv) uas tsis tau txhim kho lossis uas tau mob loj dua tom qab kho nrog lwm yam tshuaj. Nws kuj tseem siv los kho qee hom NHL hauv cov neeg uas tau muaj kev txhim kho zoo dua tom qab kho nrog lwm cov kev siv tshuaj kho mob. Ibritumomab txhaj tshuaj yog nyob hauv ib chav kawm ntawm cov tshuaj hu ua monoclonal antibodies nrog radioisotopes. Nws ua haujlwm los ntawm kev txuas rau cov qog nqaij hlav cancer thiab tso tawm hluav taws xob los ua kev puas tsuaj rau cov qog hlwb.

Txoj kev txhaj tshuaj Ibritumomab los ua kua uas yuav raug txhaj rau txoj hlab ntshav li 10 feeb los ntawm tus kws kho mob uas tau kawm los kho cov neeg mob uas siv tshuaj kho mob radioactive. Cov tshuaj no yog ib feem ntawm cov kev kho mob cancer tshwj xeeb. Nyob rau thawj hnub ntawm kev kho kab mob, koob tshuaj rituximab raug muab thiab muab thawj koob tshuaj ibritumomab txhaj tsis pub dhau 4 teev tom qab. Kev soj ntsuam kuaj seb pom kev txhaj ibritumomab kis los ntawm lub cev tau li cas 48 mus rau 72 teev tom qab txhaj tshuaj ibritumomab yog muab. Yuav soj ntsuam ntxiv yog tias yuav tsum tau ua li ob peb hnub tom ntej. Yog tias cov txiaj ntsig ntawm kev kuaj mob pom tias ibritumomab txhaj tshuaj tau kis thoob lub cev raws li qhov xav tau, koob thib ob ntawm rituximab thiab koob thib ibritumomab txhaj yuav muab 7 rau 9 hnub tom qab txhaj thawj zaug.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej txhaj tshuaj ibritumomab,

• qhia rau koj tus kws kho mob thiab kws muag tshuaj yog tias koj muaj kev fab tshuaj rau ibritumomab, ib qho ntawm cov tshuaj uas tau hais hauv ntu CEEB TOOM TSEEM CEEB, lwm yam tshuaj, lossis lwm yam tshuaj hauv ibritumomab txhaj. Nug koj tus kws kho mob lossis kws muag tshuaj rau cov npe ntawm cov khoom xyaw.
• qhia rau koj tus kws kho mob thiab kws muag tshuaj uas siv tshuaj thiab cov tshuaj uas tsis yog kws kho mob, cov vitamins, khoom noj khoom haus zoo, thiab tshuaj ntsuab koj tau noj lossis npaj yuav noj. Nco ntsoov hais txog cov tshuaj teev tseg rau ntawm ntu CEEB TOOM TSEEM CEEB. Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv.
• qhia rau koj tus kws kho mob yog tias koj tau lossis muaj ib yam muaj mob.
• qhia rau koj tus kws kho mob yog tias koj cev xeeb tub los yog npaj yuav cev xeeb tub. Koj yuav tsum tsis txhob cev xeeb tub thaum koj tau txais ibritumomab. Yog tias koj yog poj niam, koj yuav tsum tau kuaj cev xeeb tub ua ntej pib kev kho mob thiab siv tshuaj tiv thaiv kom tsis muaj menyuam kom tsis txhob muaj menyuam hauv kev kho mob thiab 12 lub hlis tom qab koj zaum kawg. Yog tias koj yog tus txiv neej nrog tus poj niam sib koom tes, siv tshuaj tiv thaiv kom tsis txhob muaj menyuam hauv plab thaum kho koj thiab 12 hlis tom qab koj zaum kawg. Yog tias koj lossis koj tus khub xeeb tub thaum tab tom txhaj tshuaj ibritumomab, hu rau koj tus kws kho mob tam sim ntawd. Kev txhaj tshuaj Ibritumomab tuaj yeem tsim kev puas tsuaj rau tus menyuam hauv plab.
• qhia rau koj tus kws kho mob yog tias koj pub mis niam lossis npaj yuav pub mis. Koj yuav tsum tsis txhob noj niam mis thaum koj tau txais ibritumomab thiab rau 6 lub hlis tom qab koj zaum kawg.
• koj yuav tsum paub tias cov tshuaj no tuaj yeem txo qis kev muaj menyuam hauv txivneej thiab pojniam. Tham nrog koj tus kws kho mob txog cov kev pheej hmoo ntawm kev txais ibritumomab.
• yog tias koj muaj kev phais, suav nrog kev phais hniav, qhia tus kws kho mob lossis kws kho hniav tias koj tau txais ibritumomab txhaj.
• tsis muaj kev txhaj tshuaj tiv thaiv thaum lub sijhawm kho thiab 12 lub hlis tom qab koj zaum kawg noj yam tsis tau tham nrog koj tus kws kho mob.
• koj yuav tsum paub tias lub xov tooj cua hluav taws xob hauv kev txhaj tshuaj ibritumomab zaum thib ob hauv koj lub cev yuav nyob ntev txog li ib asthiv tom qab koj tau txais qhov tshuaj. Txhawm rau tiv thaiv cov xov tooj cua kis mus rau cov neeg uas nyob ze koj, koj yuav tsum nco ntsoov ntxuav koj txhais tes kom huv si tom qab siv chav dej, siv hnab looj txhua zaus koj muaj kev sib deev, thiab tsis txhob sib sib hnia. Ua raws li cov lus qhia no thaum koj cov kev kho mob thiab rau 7 hnub tom qab koj tau txais koj koob tshuaj ibritumomab zaum thib ob.
• koj yuav tsum paub tias kev txhaj tshuaj ibritumomab muaj albumin (ib yam khoom uas ua los ntawm cov ntshav pub dawb). Txawm hais tias muaj tsawg heev uas cov kab mob yuav kis tau los ntawm cov ntshav, tsis muaj kis kab mob kis los ntawm cov khoom no tau tshaj tawm.
• koj yuav tsum paub tias yog tias koj tau txais ibritumomab txhaj, koj lub cev yuav tsim cov tshuaj tiv thaiv (cov tshuaj nyob rau hauv cov ntshav uas pab lub cev tiv thaiv kab mob thiab paub tua txawv teb chaws) tua cov protein. Yog tias koj tsim cov tshuaj tiv thaiv kab mob, koj yuav muaj qhov tsis haum thaum koj noj tshuaj uas ua los ntawm cov murine protein, lossis cov tshuaj no yuav tsis ua haujlwm zoo rau koj.Tom qab koj tau kho nrog ibritumomab txhaj tshuaj, nco ntsoov qhia rau koj txhua tus kws kho mob tias koj tau kho nrog ibritumomab txhaj.

Tshwj tsis yog koj tus kws kho mob hais rau koj lwm yam, txuas ntxiv koj li kev noj haus zoo.

Hu rau koj tus kws kho mob tam sim ntawd yog tias koj tsis tuaj yeem teem sijhawm tau txais kev txhaj tshuaj ibritumomab.

Ibritumomab txhaj tshuaj tuaj yeem ua rau phiv. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

• xeev siab
• ntuav
• mob plab los yog o
• cem quav
• Kev mob siab
• tsis qab los noj mov
• mob taub hau
• ntxhov siab
• kiv taub hau
• teeb meem tsis tsaug zog los yog pw tsaug zog
• nrob qaum, pob qij txha, lossis mob leeg
• yaug

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog koj muaj cov tsos mob uas teev rau hauv seem ceeb toom ceeb toom los yog ib qho ntawm cov tsos mob hauv qab no, hu rau koj tus kws kho mob tam sim ntawd:

• liab, leeg, lossis mob tawm ntawm thaj chaw uas tau txhaj tshuaj

Qee tus neeg uas tau txais tshuaj ibritumomab tau tsim lwm hom mob qog nqaij hlav cancer xws li mob leukemia (mob cancer uas pib hauv cov qe ntshav dawb) thiab mob myelodysplastic syndrome (mob uas cov qe ntshav tsis zoo li qub) thaum thawj ob peb xyoos tom qab lawv tau txais tshuaj. Tham nrog koj tus kws kho mob txog cov kev pheej hmoo ntawm kev tau txais cov tshuaj no.

Ibritumomab txhaj tshuaj tuaj yeem ua lwm cov phiv. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum tau txais cov tshuaj no.

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Cov tsos mob ntawm kev noj haus ntau heev yuav suav nrog cov hauv qab no:

• daj ntseg tawv nqaij
• tsis muaj zog
• txog siav
• nkees dhau heev lawm
• doog ntshav los ntshav tsis txawv
• ntshav me ntsis lossis thaj ua rau thaj tawv nqaij
• mob caj pas, ua npaws, ua daus no, hnoos, thiab lwm yam cim ntawm tus kab mob

Nug koj tus kws kho mob lossis kws muag tshuaj yog muaj lus nug dab tsi txog kev txhaj tshuaj ibritumomab.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

• Zevalin^®