Neutropenia - cov menyuam mos

Neutropenia yog cov ntshav tsis muaj ntshav tsis xwm yeem. Cov hlwb no hu ua neutrophils. Lawv pab lub cev tua kab mob. Kab lus no tham txog cov neutropenia hauv cov menyuam mos yug tshiab.

Cov qe ntshav dawb yog tsim hauv cov hlwb pob txha. Lawv raug tso tawm rau hauv cov hlab ntshav thiab mus ncig qhov twg xav tau. Qes ntawm cov leeg neutrophils tshwm sim thaum lub hlwb pob txha tsis tuaj yeem hloov lawv sai li xav tau.

Hauv cov menyuam mos, qhov ua kom tshwm sim feem ntau yog kis tus kab mob. Ib qho kev kis mob hnyav heev tuaj yeem ua rau neutrophils siv sai sai. Nws kuj tseem tuaj yeem tiv thaiv cov leeg pob txha los ntawm kev tsim cov neutrophils ntau dua.

Qee zaum, cov menyuam mos uas tsis mob yuav ua rau lub cev tsis muaj zog vim tias tsis muaj laj thawj. Qee qhov kev tsis haum xeeb hauv niam cev xeeb tub, xws li preeclampsia, tuaj yeem tuaj yeem ua rau cov neutropenia hauv cov menyuam mos.

Muaj qee zaus, cov niam yuav muaj cov tshuaj tiv thaiv tiv thaiv lawv cov menyuam mos liab neutrophils. Cov tshuaj tiv thaiv kab mob no hla lub tsho ua ntej yug thiab ua rau tus me nyuam lub hlwb tawg (alloimmune neutropenia). Muaj qee zaus, muaj teeb meem menyuam hlwb pob txha yuav ua rau cov qe ntshav dawb tsawg.

Qhov hnoos qeev me me ntawm cov me nyuam cov ntshav yuav muab xa mus rau qhov chaw kuaj ntshav kom ua tiav cov ntshav (CBC) thiab cov ntshav sib txawv. A CBC nthuav tawm tus lej thiab hom ntawm cov qe ntshav hauv cov ntshav. Qhov txawv yuav pab txiav txim seb muaj pes tsawg cov qe ntshav dawb nyob hauv cov ntshav ntsuas.

Qhov chaw ntawm kev kis kab mob yuav tsum pom thiab kho.

Feem ntau, neutropenia ploj mus nws tus kheej vim tias tus hlwb pob txha rov qab thiab pib tsim muaj cov qe ntshav dawb txaus.

Muaj qee zaus thaum neutrophil suav muaj tsawg tsawg txaus rau kev phom sij txog lub neej, kev kho mob hauv qab no tuaj yeem pom zoo:

• Tshuaj kho mob los txhawb kev tsim cov qe ntshav dawb
• Antibodies los ntawm kev muab cov ntshav kuaj (cov ntshav hauv lub cev globulin)

Kev xav ntawm tus menyuam yog nyob ntawm qhov ua rau lub hlwb neutropenia. Qee qhov mob thiab lwm yam mob ntawm cov menyuam mos tshiab tuaj yeem tsim kev phom sij txog lub neej. Txawm li cas los xij, feem ntau tus kab mob tsis ua rau muaj kev mob tshwm sim mus ntev tom qab lub hlwb neutropenia ploj mus lossis kho tau.

Alloimmune neutropenia tseem yuav tau zoo dua thaum leej niam cov tshuaj tiv thaiv tawm ntawm tus menyuam cov ntshav.

• Neutrophils

Benjamin JT, Torres BA, Maheshwari A. Neonatal leukocyte physiology thiab kev cuam tshuam. Hauv: Gleason CA, Juul SE, eds. Avery Cov Kab Mob ntawm Cov Menyuam MosCov. 10 tus ed. Philadelphia, PA: Elsevier; 2018: chap 83.

Koenig JM, Bliss JM, Mariscalco MM. Cev xeeb tub neutrophil lub cev tsis meej thiab tsis txawv ntawm cov menyuam mos. Hauv: Polin RA, Abman SH, Rowitch DH, Benitz WE, Fox WW, eds. Fetal thiab Neonatal PhysiologyCov. Thib 5 ed. Philadelphia, PA: Elsevier; 2017: chap 126.

Letterio J, Ahuja S. Hematologic teeb meem. Hauv: Fanaroff AA, Fanaroff JM, eds. Klaus thiab Fanaroff's Saib Xyuas Txog Cov Kev Ruaj Ntseg NeonateCov. 7 tus ed. St Louis, MO: Elsevier; 2020: chap 16.