Kev kuaj ntshav ACTH

Kev xeem ACTH ntsuas txog theem ntawm adrenocorticotropic hormone (ACTH) hauv cov ntshav. ACTH yog yam tshuaj uas tso tawm hauv lub hlwb pituitary hauv lub hlwb.

Xav tau cov ntshav ntxiv.

Koj tus kws khomob yuav hais kom koj mus kuaj thaum sawv ntxov. Qhov no yog qhov tseem ceeb, vim tias qib cortisol nws txawv thoob plaws rau hnub ntawd.

Nws tseem yuav kom koj tsis txhob noj tshuaj uas cuam tshuam rau kev kuaj mob. Cov tshuaj no suav nrog glucocorticoids xws li prednisone, hydrocortisone, lossis dexamethasone. (Tsis txhob tsum tsis txhob tso tseg cov tshuaj no tshwj tsis yog koj tus kws kho mob hais kom ua.)

Thaum cov koob tau tso rau hauv cov ntshav, qee cov neeg hnov ​​mob me ntsis. Lwm tus ho hnov ​​tus mob lossis ceg tawv xwb. Tom qab ntawd, tej zaum yuav muaj qee qhov duav lossis pob me me. Tsis ntev no ploj mus.

Lub luag haujlwm tseem ceeb ntawm ACTH yog tswj hwm glucocorticoid (steroid) hormone cortisol. Cortisol tawm hauv cov qog adrenal. Nws tswj ntshav siab, ntshav qab zib cov ntshav, ua kom lub cev tsis muaj zog thiab cov lus teb rau kev ntxhov siab.

Qhov kev ntsuam xyuas no tuaj yeem pab pom qhov ua rau qee yam teeb meem hormone.

Cov txiaj ntsig zoo rau kev kuaj ntshav thaum sawv ntxov yog 9 txog 52 pg / mL (2 txog 11 teev tsaus ntuj / L).

Cov kab ke tus nqi yuav txawv me ntsis ntawm ntau lub chaw soj nstuam. Qee qhov kuaj pom siv cov kev ntsuas sib txawv lossis sim cov qauv sib txawv. Tham nrog koj tus kws kho mob hais txog lub ntsiab lus ntawm koj cov kev sim tshwj xeeb.

Qib dua-dua-li ib txwm ntawm ACTH yuav qhia tau tias:

• Cov qog adrenal tsis tsim txaus cortisol (Addison disease)
• Cov qog adrenal tsis tsim cov tshuaj hormones txaus (Congenital adrenal hyperplasia)
• Ib lossis ntau dua ntawm cov qog endocrine muaj ntau dhau los yog tau tsim cov qog (ntau yam endocrine neoplasia hom I)
• Pituitary ua ntau dhau ACTH (Cushing disease), uas feem ntau ua rau los ntawm qog ntshav tsis mob qog ua rau lub qog pituitary.
• Muaj tsawg hom mob qog (ntsws, thyroid, lossis mob thiav) ua ntau dhau ntawm ACTH (mob nqaij hlav hauv lub hlwb)

Qhov qis-dua-li ib txwm ntawm ACTH yuav qhia tau tias:

• Cov tshuaj Glucocorticoid yog suppress ACTH ntau lawm (feem ntau)
• Pituitary caj pas tsis tsim cov tshuaj hormones txaus, xws li ACTH (hypopituitarism)
• Cov qog ntawm qog adrenal uas ua rau cortisol ntau dhau

Txoj kev pheej hmoo me ntsis nrog kev coj koj cov ntshav mus. Cov leeg thiab cov hlab ntsha sib txawv raws li ib tug neeg mus rau lwm qhov thiab ntawm ib sab ntawm lub cev mus rau lwm qhov. Noj ntshav los ntawm qee tus neeg yuav nyuaj dua li lwm tus.

Lwm yam kev phom sij los cuam tshuam nrog kev kos ntshav me ntsis tab sis yuav suav nrog:

• Los ntshav ntau
• Tsaus muag lossis hnov ​​nkaus lub teeb
• Ntau cov punctures los nrhiav cov leeg ntshav
• Hematoma (ntshav ntau nyob hauv qab daim tawv nqaij)
• Kev kis tus kab mob (muaj kev pheej hmoo me me txhua lub sijhawm ntawm daim tawv tawg)

Serum adrenocorticotropic cov tshuaj hormones; Adrenocorticotropic cov tshuaj hormones; Highly-rhiab ACTH

• Cov qog endocrine

Chernecky CC, Berger BJ. Adrenocorticotropic hormone (ACTH, corticotropin) - ntshav dej. Hauv: Chernecky CC, Berger BJ, eds. Kev kuaj thiab kuaj mobCov. 6 tus ed. St Louis, MO: Elsevier Saunders; Xyoo 2013: 107.

Melmed S, Kleinberg D. Pituitary pawg thiab qog. Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Williams Phau Ntawv ntawm EndocrinologyCov. 13th ed. Philadelphia, PA: Elsevier; 2016: chap 9.

Stewart PM, Newell-Nqe JDC. Lub adrenal cortex. Hauv: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Williams Phau Ntawv ntawm EndocrinologyCov. 13th ed. Philadelphia, PA: Elsevier; 2016: chap 15.