Ntshav dej globulin electrophoresis

Ntsuas cov tshuaj globulin electrophoresis ntsuas ntsuas cov qib ntawm cov protein hu ua globulins nyob rau ntu ntawm cov kua ntshav. Cov kua dej no hu ua ntshiab dej.

Xav tau cov ntshav ntxiv.

Hauv tsev kuaj sim, tus kws sim tso ntshav tso rau ntawm daim ntawv tshwj xeeb thiab siv hluav taws xob hluav taws xob. Cov protein txav mus rau ntawm daim ntawv thiab qauv sib dhos uas qhia qhov ntau npaum li cas ntawm txhua cov protein.

Ua raws li cov lus qhia seb koj yuav tsum yoo mov ua ntej qhov kev kuaj no.

Qee cov tshuaj yuav cuam tshuam qhov tshwm sim ntawm qhov kev ntsuas no. Koj tus kws kho mob yuav qhia koj yog tias koj xav tau tsis noj tshuaj dab tsi ntxiv. Tsis txhob tsum tsis noj cov tshuaj ua ntej tham nrog koj tus kws kho mob.

Thaum cov koob tau tso rau hauv cov ntshav, qee cov neeg hnov ​​mob me ntsis. Lwm tus ho hnov ​​tus mob lossis ceg tawv xwb. Tom qab ntawd, tej zaum yuav muaj qee qhov thos lossis me me sib duav. Tsis ntev no ploj mus.

Kev kuaj ntshav no yog ua los saib cov protein globulin nyob rau hauv cov ntshav. Txheeb xyuas cov hom globulins tuaj yeem pab tshawb xyuas qee yam teeb meem kev kho mob.

Globulins yog ntxaib raug faib ua peb pawg: alpha, beta, thiab gamma globulins. Gamma globulins suav nrog ntau yam tshuaj tiv thaiv xws li immunoglobulins (Ig) M, G, thiab A.

Qee yam kab mob cuam tshuam nrog kev tsim ntau yam tshuaj immunoglobulins. Piv txwv, Waldenstrom macroglobulinemia yog ib hom mob cancer ntshav qee cov qe ntshav dawb. Nws txuas nrog tsim cov tshuaj tiv thaiv IgM ntau dhau.

Tus nqi yog li qub yog:

• Ntshav dej globulin: 2.0 txog 3.5 grams rau ib deciliter (g / dL) lossis 20 txog 35 grams tauj ib liter (g / L)
• IgM tivthaiv: 75 txog 300 milligrams ib deciliter (mg / dL) lossis 750 txog 3,000 milligrams ib zaug twg (mg / L)
• IgG tivthaiv: 650 txog 1,850 mg / dL lossis 6.5 txog 18.50 g / L
• IgA tivthaiv: 90 txog 350 mg / dL lossis 900 rau 3,500 mg / L

Cov kab ke tus nqi yuav txawv me ntsis ntawm ntau lub chaw soj nstuam. Qee qhov kuaj pom siv cov kev ntsuas sib txawv lossis kuaj cov qauv sib txawv. Tham nrog koj tus kws kho mob txog cov ntsiab lus ntawm koj cov kev kuaj sim.

Nce gamma globulin protein ntau yuav qhia tias:

• Mob yooj yim
• Mob ntshav thiab mob rau cov hlwb pob txha nrog rau ntau yam mob myeloma, thiab qee qhov lymphomas thiab leukemias
• Kev tiv thaiv kab mob tsis haum
• Lub sij hawm ntev (mob) kab mob inflammatory (piv txwv li, mob caj dab thiab mob caj dab lupus erythematosus)
• Waldenström macroglobulinemia

Qhov feem ntau yuav muaj feem tsawg nrog qhov kev coj koj cov ntshav mus. Cov leeg thiab cov hlab ntsha sib txawv raws li ib tug neeg mus rau lwm tus, thiab los ntawm ib sab ntawm lub cev mus rau lwm qhov. Noj ntshav los ntawm qee tus neeg yuav nyuaj dua li lwm tus.

Lwm yam kev phom sij los cuam tshuam nrog kev kos ntshav me ntsis, tab sis yuav suav nrog:

• Los ntshav ntau
• Tsaus muag lossis hnov ​​nkaus lub teeb
• Ntau cov punctures los nrhiav cov leeg ntshav
• Hematoma (ntshav buildup hauv qab daim tawv nqaij)
• Kev kis tus kab mob (muaj kev pheej hmoo me me txhua lub sijhawm ntawm daim tawv tawg)

Kev siv tshuaj tiv thaiv kab mob ntshav qog

• Kuaj ntshav

Chernecky CC, Berger BJ. Immunoelectrophoresis - ntshav dej thiab zis. Hauv: Chernecky CC, Berger BJ, eds. Kev kuaj thiab kuaj mobCov. 6 tus ed. St Louis, MO: Elsevier Saunders; Xyoo 2013: 667-692.

Dominiczak MH, Fraser WD. Cov ntshav thiab cov ntshav protein. Hauv: Baynes JW, Dominiczak MH, eds. Kev Kho Mob BiochemistryCov. Thib 5 ed. Philadelphia, PA: Elsevier; 2019: chap 40.