Neuroblastoma

Neuroblastoma yog ib hom qog nqaij hlav qog ntshav tsawg uas tsim los ntawm cov hlab ntaws. Feem ntau nws tshwm sim hauv menyuam mos thiab menyuam yaus.

Neuroblastoma tuaj yeem tshwm sim hauv ntau qhov chaw ntawm lub cev. Nws tshwm sim los ntawm cov ntaub so ntswg uas tsim cov tshuaj tiv thaiv mob siab. Nov yog ib feem ntawm cov leeg hlwb uas tswj lub cev ua haujlwm, xws li lub plawv dhia thiab ntshav siab, kev zom zaub mov, thiab cov qib qee yam tshuaj hormones.

Feem ntau neuroblastomas pib hauv plab, hauv adrenal caj pas, ze ntawm tus txha caj qaum, lossis hauv siab. Neuroblastomas tuaj yeem sib kis mus rau cov pob txha. Cov pob txha muaj xws li cov ntsej muag, pob txha taub hau, lub ntsej muag, lub xub pwg, caj npab, thiab ceg. Nws kuj tseem kis tau rau tus pob txha, mob siab, cov qog ntshav, tawv nqaij, thiab ncig ntawm lub qhov muag (ncig).

Cov ua rau cov qog ntshav tsis paub. Cov kws tshaj lij ntseeg tias kev kho tsis zoo nyob hauv cov caj ces ua lub luag haujlwm. Ib nrab ntawm cov qog tau nyob rau thaum yug. Neuroblastoma feem ntau pom muaj tshwm sim rau cov menyuam yaus ua ntej muaj hnub nyoog ntawm 5. Txhua xyoo muaj thaj tsam ntawm 700 tus neeg mob nyob hauv Tebchaws Meskas. Qhov kev cuam tshuam no tshwm sim me ntsis rau cov tub.

Feem ntau ntawm cov neeg, lub qog tau kis thaum nws kuaj thawj zaug.

Cov tsos mob thawj zaug feem ntau yog ua npaws, qhov koj paub (mob), thiab mob. Kuj tseem yuav muaj poob qab los noj mov, yuag, thiab raws plab.

Lwm cov tsos mob nyob ntawm qhov chaw ntawm lub qog, thiab tej zaum yuav suav nrog:

• Mob pob txha los yog mob (yog tias mob cancer tau kis rau cov pob txha)
• Ua pa nyuaj lossis hnoos ntev (yog tias mob cancer tau kis mus rau lub hauv siab)
• Luag mob plab (los ntawm lub qog loj lossis cov kua ntau dhau)
• Ua ntsej muag liab, tawv nqaij liab
• Tawv nqaij daj thiab xiav xiav ib ncig ntawm lub qhov muag
• Yawg hws hws
• Lub plawv dhia nrawm (tachycardia)

Teeb meem hauv lub hlwb thiab lub paj hlwb kuj suav nrog:

• Cev tsis taus zais zis
• Poob ntawm kev txav (tuag tes tuag taw) ntawm lub duav, ob txhais ceg, lossis taw (qis qis dua)
• Teeb meem kev tshuav nyiaj
• Kev tswj tsis tau tus muag qhov muag lossis txhais ko taw thiab taw taw (hu ua opsoclonus-myoclonus syndrome, lossis "seev cev qhov muag thiab seev cev taw")

Tus kws saib xyuas kev noj qab haus huv yuav tshuaj xyuas tus menyuam. Ua raws li qhov chaw ntawm lub qog:

• Tej zaum yuav muaj cov qog lossis cov tawv nqaij hauv lub plab.
• Lub siab yuav nce, yog tias cov qog ua tawm mus rau daim siab.
• Tej zaum yuav muaj ntshav siab thiab lub plawv dhia ceev yog cov qog ua haujlwm nyob rau hauv cov qog adrenal.
• Cov qog ntshav yuav o tuaj.

Xoo hluav taws xob los sis lwm yam kev soj ntsuam ntsuas tau los nrhiav cov qog loj (thawj) thiab saib seb nws kis mus rau qhov twg. Cov no suav nrog:

• Cov pob txha scan
• Ua pob xoo hluav taws xob
• Kev ntsuas hluav taws xob xoo
• CT scan ntawm lub hauv siab thiab lub plab
• MRI scan ntawm lub hauv siab thiab lub plab

Lwm yam kev xeem uas yuav muaj xws li:

• Mob me ntawm lub qog
• Nqaij pob txha caj dab
• Ua kom tiav cov ntshav suav (CBC) uas qhia tias muaj ntshav lossis lwm yam txawv txav
• Kev tshawb fawb coagulation thiab tus nqi erythrocyte sedimentation (ESR)
• Kuaj Hormone (kuaj ntshav los xyuas cov qib tshuaj hormones xws li catecholamines)
• MIBG scan (kuaj cov duab kos kom paub meej tias muaj neuroblastoma)
• Tso zis 24-teev ntsuas rau catecholamines, homovanillic acid (HVA), thiab vanillymandelic acid (VMA)

Kev kho mob nyob ntawm:

• Qhov chaw ntawm lub qog
• Ntau npaum li cas thiab nyob qhov twg cov qog tau kis mus
• Tus neeg muaj hnub nyoog

Hauv qee kis, kev phais ib leeg xwb txaus. Feem ntau, tab sis, lwm txoj kev kho mob yog qhov xav tau ib yam nkaus. Tshuaj tua kab mob anticancer (tshuaj kho mob) yuav pom zoo yog tias lub qog tau kis.Kev siv hluav taws xob tua kuj tseem siv tau.

Kev siv tshuaj kho mob siab rau kev kho mob, kev hloov kho lub hlwb qog hloov ntshav, thiab kev kho tshuaj tiv thaiv kab mob kuj tseem siv.

Koj tuaj yeem daws kev ntxhov siab ntawm kev muaj mob los ntawm kev koom nrog pawg pab txhawb mob qog noj ntshav. Kev qhia rau lwm tus uas muaj kev paub ntau yam thiab teeb meem tuaj yeem pab koj thiab koj tus me nyuam tsis xav ib leeg.

Qhov tshwm sim nws txawv. Hauv cov menyuam yaus me, lub qog yuav ploj mus nws ib leeg, yam tsis tau kho. Los yog, cov nqaij ntawm cov qog yuav loj hlob thiab loj hlob mus rau hauv cov qog uas tsis yog mob qog nqaij hlav hu ua ganglioneuroma, uas tuaj yeem tshem tawm mob tawm. Hauv lwm qhov xwm txheej, cov kabmob kis tau sai.

Teb rau kev kho mob kuj txawv. Txoj kev kho yog feem ntau muaj kev vam meej yog tias tus mob cancer tsis kis. Yog tias nws kis, neuroblastoma nws nyuaj rau kho tus mob. Cov menyuam yaus me feem ntau ua tau zoo dua cov menyuam yaus dua.

Cov menyuam yaus kho tus mob neuroblastoma tuaj yeem muaj feem pheej hmoo ntxiv zaum ob, yuav ua rau mob cancer txawv rau yav tom ntej.

Teeb meem yuav suav nrog:

• Kis (metastasis) ntawm cov qog
• Kev puas tsuaj thiab ploj ntawm kev ua haujlwm ntawm cov kabmob

Hu rau koj tus kws kho mob yog tias koj tus menyuam muaj mob neuroblastoma. Kev paub thiab kho thaum ntxov yog txoj hauv kev zoo.

Cancer - neuroblastoma

• Neuroblastoma hauv lub siab - CT scan

Dome JS, Rodriguez-Galindo C, Spunt SL, Santana VM. Kev sib tw cov kabmob tawv nqaij. Hauv: Niederhuber JE, Armitage JO, Doroshow JH, Kastan MB, Tepper JE, eds. Abeloff's Clinical OncologyCov. Thib 5 ed. Philadelphia, PA: Elsevier Saunders; Xyoo 2014: chap 95.

Lub koom haum Cancer National website. Kev kho cov tshuaj Neuroblastoma (PDQ) - cov kws kho mob kom zoo ntxiv. www.cancer.gov/types/neuroblastoma/hp/neuroblastoma-nyuj-pdq. Hloov tshiab Lub Yim Hli 17, 2018. Nkag mus Lub Kaum Ib Hlis 12, 2018.