Mob qog noj ntshav - nqaij hlav hauv hlwb

Medullary carcinoma ntawm lub qog yog mob qog ua rau cov thyroid caj pas uas pib hauv cov cell uas tso cov tshuaj hu ua calcitonin. Cov hlwb no hu ua "C" hlwb. Lub qog ua haujlwm nyob hauv koj lub caj dab qis.

Qhov ua rau mob qog nqaij hlav cancer ntawm cov thyroid (MTC) tsis paub meej. MTC muaj tsawg heev. Nws tuaj yeem tshwm sim hauv cov menyuam yaus thiab cov neeg laus.

Tsis zoo li lwm hom mob qog noj ntshav qog, MTC tsis tshua muaj kev cuam tshuam los ntawm kev kho hluav taws xob rau lub caj dab uas muab rau kho lwm cov qog nqaij hlav thaum yau.

Muaj ob daim ntawv ntawm MTC:

• Sporadic MTC, uas tsis khiav hauv tsev neeg. Feem ntau ntawm MTCs yog cov seem tsis paub. Daim ntawv no feem ntau cuam tshuam rau cov laus.
• Cov Ntawv Pov Thawj MTC, uas khiav hauv tsev neeg.

Koj muaj feem kis mob kheesxaws ntau dua yog tias koj muaj:

• Tsev neeg keeb kwm ntawm MTC
• Tsev neeg keeb kwm ntawm ntau yam keeb endocrine neoplasia (MEN)
• Cov keeb kwm ua ntej dhau los ntawm pheochromocytoma, mucosal neuromas, hyperparathyroidism lossis pancreatic endocrine hlav

Lwm hom mob qog noj ntshav muaj xws li:

• Carcinoma Anaplastic ntawm lub qog
• Cov hlav qog ntawm cov qog
• Papillary carcinoma ntawm lub qog
• Lub qog ua qog ua ntshav

MTC feem ntau pib ua cov qog me me (nodule) hauv lub qog ua haujlwm lub qog. Kuj tseem muaj qog ntshav o nyob ntawm caj dab. Raws li qhov tshwm sim, cov tsos mob yuav suav nrog:

• O caj dab o
• Khuam
• Cov teeb meem ua pa vim yog txoj hlab pa nqaim
• Hnoos
• Hnoos nrog ntshav
• Mob plab zom mov vim yog qib calcitonin ntau

Koj tus kws kho mob yuav kuaj ib ce thiab nug txog koj cov tsos mob thiab keeb kwm kev kho mob.

Kev ntsuam xyuas uas yuav siv los kuaj MTC muaj xws li:

• Kev kuaj ntshav calcium Calcononin
• CEA kuaj ntshav
• Kev tshuaj ntsuam caj ces
• Lub qog ua ntshav
• Ultrasound ntawm cov qog thiab cov qog ntshav ntawm lub caj dab
• TSIAJ scan

Cov neeg muaj MTC yuav tsum kuaj xyuas lwm cov qog, tshwj xeeb tshaj yog pheochromocytoma thiab parathyroid hlav thiab parathyroid hlav.

Txoj kev kho yog hais txog kev phais mob kom tshem tawm cov thyroid caj pas thiab cov qog ntshav nyob ib puag ncig. Vim tias qhov no yog cov qog uas tsis tshua pom tshwm sim, kev phais yuav tsum tau ua los ntawm tus kws phais neeg paub zoo txog hom mob qog nqaij hlav no thiab tau ntsib nrog kev ua haujlwm xav tau.

Kev kho mob ntxiv yuav yog nyob ntawm koj cov calcitonin ntau ntau. Ib qho kev nce qib ntawm calcitonin ntau dua tuaj yeem qhia qhov tshiab ntawm kev mob qog noj ntshav.

• Kev siv tshuaj kho mob thiab hluav taws xob tsis ua haujlwm zoo rau hom mob qog nqaij hlav no.
• Hluav taws xob tau siv qee tus neeg tom qab phais mob.
• Cov kev siv tshuaj kho dua tshiab tuaj yeem txo qog kom loj hlob. Koj tus kws khomob tuaj yeem qhia koj ntau ntxiv txog cov no, yog xav tau.

Cov nyob ze cov neeg txheeb ze ntawm cov neeg muaj tus mob muaj keeb kwm ntawm MTC yog cov muaj pheej hmoo yuav mob cancer thiab yuav tsum tham nrog cov muab kev pab.

Koj tuaj yeem daws kev ntxhov siab ntawm kev muaj mob los ntawm kev koom nrog pawg pab txhawb mob qog noj ntshav. Faib qhia rau lwm tus uas muaj kev paub thiab teeb meem ntau yam tuaj yeem pab koj tsis txhob xav tias yog ib leeg.

Feem ntau cov neeg muaj MTC nyob tsawg kawg 5 xyoos tom qab kuaj mob, nyob ntawm theem mob cancer. Tus nqi 10-lub xyoo nyob nrog yog 65%.

Teeb meem yuav suav nrog:

• Cov kabmob kheesxaws kis mus rau lwm thaj chaw hauv lub cev
• Parathyroid qog yog yuam kev tshem tawm thaum phais

Hu rau koj tus kws kho mob yog tias koj muaj cov tsos mob ntawm MTC.

Kev tiv thaiv tej zaum yuav ua tsis tau. Tab sis, kom paub txog koj cov teeb meem pheej hmoo, tshwj xeeb yog koj tsev neeg keeb kwm, tuaj yeem tso cai kuaj thiab kho mob ntxov. Rau cov neeg uas muaj keeb kwm tsev neeg muaj zog heev ntawm MTC, kev xaiv tshem tawm cov thyroid caj pas tuaj yeem pom zoo. Koj yuav tsum ua tib zoo sib tham txog cov kev xaiv no nrog tus kws kho mob uas paub txog tus mob.

Lub qog - nqaij hlav hauv nruab nrab; Mob Cancer - cov qog (mob nqaij hlav cancer); MTC; Lub qog nodule - medullary

• Mob qog noj ntshav - CT scan
• Lub qog ua haujlwm

Jonklass J, Cooper DS. Lub qog. Hauv: Goldman L, Schafer AI, eds. Goldman-Cecil TshuajCov. 26th ed. Philadelphia, PA: Elsevier; 2020: cha 213.

Lub koom haum Cancer National website. Kev kho mob qog noj ntshav (cov neeg laus) (PDQ) - kev noj qab haus huv tshaj lij. www.cancer.gov/types/thyroid/hp/thyroid-nyuj-pdq. Hloov kho Lub Ib Hlis 30, 2020. Nkag mus rau Lub Peb Hlis 6, 2020.

Smith PW, Hanks LR, Salomone LJ, Hanks JB. Lub qog. Hauv: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Phau Ntawv Txog Kev Kho MobCov. 20 tus ed. Philadelphia, PA: Elsevier Saunders; 2017: cha 36.

Viola D, Elisei R. Kev tswj hwm ntawm cov mob qog nqaij hlav cancer medullary. Endocrinol Metab Clin North AmCov. 2019; 48 (1): 285-301. PMID: 30717909 pubmed.ncbi.nlm.nih.gov/30717909/.

Wells SA Jr, Asa SL, Dralle H. Lub Koomhaum Cov Neeg Asmeskas Cov Ncauj Qog Kev Cai los ua kom muaj kev tswj hwm ntawm cov qog nqaij hlav hauv koj lub cev. Lub qogCov. Xyoo 2015; 25 (6): 567-610. PMID: 25810047 pubmed.ncbi.nlm.nih.gov/25810047/.