Quantitative Bence-Jones kev ntsuam xyuas cov protein

Qhov ntsuas no yuav ntsuas cov qib ntawm cov protein tsis sib luag hu ua Bence-Jones cov protein hauv cov zis.

Qhov yuav kuaj tau cov zis kom huv. Txoj kev ntxuav kom huv yog siv los tiv thaiv kab mob los ntawm chaw mos lossis chaw mos los nkag rau hauv cov zis. Txhawj koj cov zis, tus kws kho mob yuav muab ib pob khoom tshwj xeeb rau koj uas muaj cov tshuaj ntxuav thiab ntaub so huv huv. Ua raws li cov lus qhia ua kom pom tseeb tias qhov ntsuas tau raug.

Cov qauv yog xa mus rau qhov kuaj sim. Muaj, ib qho ntawm ntau txoj hauv kev yog siv los txhawm rau paub cov nqaijrog Bence-Jones. Ib txoj kev, hu ua immunoelectrophoresis, yog qhov tseeb tshaj plaws.

Qhov kev kuaj mob tsuas yog tso zis ib txwm, thiab tsis muaj qhov tsis xis nyob.

Cov protein Bence-Jones yog ib feem ntawm cov tshuaj tiv thaiv ib txwm hu ua cov saw sib txuas. Cov protein no tsis nquag muaj zis. Qee zaum, thaum koj lub cev ua rau cov tshuaj tiv thaiv ntau dhau, cov theem ntawm cov saw hlau tseem nce siab. Cov protein Bence-Jones yog qhov me me uas tau lim tawm los ntawm ob lub raum. Cov protein ces nchuav rau hauv zis.

Koj tus kws khomob yuav xaj kom kuaj li no:

• Txhawm rau kuaj xyuas cov mob uas ua rau muaj protein nyob hauv cov zis
• Yog tias koj muaj protein ntau hauv koj cov zis
• Yog tias koj muaj cim qhia tias mob ntshav hu ua myeloma

Qhov tshwm sim ib txwm txhais tau tias tsis muaj cov protein Bence-Jones nrhiav tau hauv koj cov zis.

Cov protein Bence-Jones tsis tshua pom muaj nyob hauv cov zis. Yog tias lawv, nws feem ntau cuam tshuam nrog ntau yam mob myeloma.

Ib qho kev txawv txav tshwm sim kuj yog vim:

• Ib qho txawv txav ntawm cov protein hauv cov nqaij thiab cov plab hnyuv siab raum (amyloidosis)
• Kab mob ntshav hu ua lymphocytic mob ntshav qab zib
• Lymph system cancer (qog ntshav)
• Buildup hauv cov ntshav ntawm cov protein hu ua M-protein (monoclonal gammopathy ntawm qhov tsis paub qhov tseem ceeb; MGUS)
• Mob raum tsis ua hauj lwm

Tsis muaj kev pheej hmoo nrog qhov kev ntsuas no.

Immunoglobulin teeb cov saw - zis; Zis Bence-Jones cov protein

• Txiv neej urinary system

Chernecky CC, Berger BJ. Protein electrophoresis - tso zis. Hauv: Chernecky CC, Berger BJ, eds. Kev kuaj thiab kuaj mobCov. 6 tus ed. St Louis, MO: Elsevier Saunders; Xyoo 2013: 920-922.

Riley RS, McPherson RA. Kev kuaj mob ntawm cov zis. Hauv: McPherson RA, Pincus MR, eds. Henry's Kev Kuaj Mob thiab Kev Tswj Xyuas los ntawm Laboratory Txoj KevCov. 23rd ed. St Louis, MO: Elsevier; 2017: chap 28.

Rajkumar SV, Dispenzieri A. Ntau yam myeloma thiab cuam tshuam cuam tshuam. Hauv: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical OncologyCov. 6 tus ed. Philadelphia, PA: Elsevier; 2020: cha 101.