Mob carcinoid

Tus mob carcinoid syndrome yog ib pab cov tsos mob cuam tshuam nrog cov qog nqaij hlav carcinoid. Cov no yog cov qog ntawm cov hnyuv, cov hnyuv, hnyuv tws, thiab hlab ntsws hauv lub ntsws.

Carcinoid syndrome yog cov qauv ntawm cov tsos mob qee zaum pom hauv cov neeg uas muaj qog nqaij hlav cancer. Cov hlav no muaj tsawg, thiab feem ntau qeeb hlob. Feem ntau cov qog carcinoid muaj nyob hauv txoj hnyuv thiab lub ntsws.

Carcinoid syndrome tshwm sim nyob rau ob peb tus neeg muaj carcinoid qog, tom qab lub qog tau kis mus rau lub siab lossis lub ntsws.

Cov qog no tso tawm ntau dhau ntawm cov hormone serotonin, nrog rau ntau lwm yam tshuaj. Cov tshuaj hormones ua rau cov hlab ntshav qhib (ntxiv). Qhov no ua rau cov carcinoid syndrome.

Cov carcinoid syndrome tau ua los ntawm plaub qhov tsos mob nrog:

• Tso dej (lub ntsej muag, caj dab, lossis sab hauv siab), xws li nthuav tawm cov hlab ntshav uas pom ntawm daim tawv nqaij (telangiectasias)
• Ua pa nyuaj, xws li hawb pob
• Zawv plab
• Cov teeb meem mob plawv, xws li to lub plawv dhia, lub plawv dhia qeeb, tsis muaj ntshav siab lossis ntshav siab

Cov tsos mob qee zaum kuj tshwm sim los ntawm kev tawm dag zog ntawm lub cev, lossis noj zaub mov lossis haus dej haus xws li cheese xiav, chocolate, lossis caw liab.

Feem ntau ntawm cov qog tau pom thaum kuaj lossis cov txheej txheem ua rau lwm qhov laj thawj, xws li thaum phais plab.

Yog tias kuaj lub cev tas, tus kws saib xyuas kev noj qab haus huv yuav pom cov cim ntawm:

• Lub plawv dhia teeb meem, xws li suab yws
• Kab mob Niacin-deficiency (pellagra)

Kev ntsuam xyuas uas yuav ua tau muaj xws li:

• 5-HIAA theem tso zis
• Kuaj ntshav (suav nrog serotonin thiab chromogranin ntshav kuaj)
• CT thiab MRI scan ntawm lub hauv siab lossis lub plab
• Echocardiogram
• Octreotide radiolabeled scan

Kev phais mus tshem tawm cov qog feem ntau yog thawj txoj kev kho mob. Nws tuaj yeem kho tus mob mus tas li yog tias cov qog tshem tawm tag nrho.

Yog tias lub qog tau kis mus rau lub siab, kev kho mob cuam tshuam nrog rau cov hauv qab no:

• Tshem cov chaw ntawm daim siab uas muaj cov qog ua qog
• Xa (infusing) tshuaj ncaj qha mus rau daim siab ua kom cov qog

Thaum tag nrho cov qog tshem tawm tsis tuaj yeem tshem tawm, tshem tawm feem ntau ntawm cov qog ("debulking") tuaj yeem pab txo cov tsos mob.

Kev txhaj tshuaj Octreotide (Sandostatin) lossis lanreotide (Somatuline) yog muab rau cov neeg mob qog nqaij hlav cancer uas tsis tuaj yeem raug tshem tawm nrog kev phais mob.

Cov neeg muaj tus mob carcinoid syndrome yuav tsum zam tus cawv, noj mov loj, thiab zaub mov ntau hauv cov tyramine (cov laus cheeses, avocado, ntau cov zaub mov tiav), vim tias lawv yuav ua rau cov tsos mob tshwm sim.

Qee hom tshuaj siv, xws li xaiv serotonin reuptake inhibitors (SSRIs), xws li paroxetine (Paxil) thiab fluoxetine (Prozac), tuaj yeem ua rau cov tsos mob hnyav dua los ntawm kev nce qib ntawm serotonin. Txawm li cas los xij, TSIS TXHOB siv cov tshuaj no tshwj tsis yog koj tus kws kho mob hais kom koj ua.

Kawm paub ntau ntxiv ntawm cov carcinoid syndrome thiab tau txais kev txhawb nqa los ntawm:

• Foundation Carcinoid Cancer Foundation - www.carcinoid.org/resources/support-groups/directory/
• Neuroendocrine Cov Kev Tshawb Fawb Qog Pob Zeb - netrf.org/for-patients/

Qhov tsis pom kev nyob hauv cov neeg mob carcinoid syndrome kuj txawv dua li qhov pom ntawm cov neeg uas muaj cov qog nqaij hlav carcinoid tsis muaj tus mob.

Kev kuaj mob kuj yog nyob ntawm qhov chaw ntawm qog thiab. Hauv cov neeg muaj tus mob no, cov qog feem ntau tau kis mus rau lub siab. Qhov no ua kom qis dua kev ua neej nyob. Cov neeg muaj tus mob carcinoid syndrome kuj yuav muaj tus mob qog nqaij hlav ntau (cov thawj ob lub qog nqaij hlav) tib lub sijhawm. Zuag qhia tag nrho, kev ntsuas feem ntau yog qhov ua tau zoo.

Teeb meem ntawm cov mob carcinoid syndrome tuaj yeem suav nrog:

• Nce kev pheej hmoo ntawm kev ntog thiab raug mob (los ntawm ntshav siab)
• Txoj hnyuv tawm (los ntawm qog)
• Lub plab zom mov txhaws ntshav
• Lub plawv dhia tsis ua haujlwm

Daim ntawv tuag ntawm cov mob carcinoid syndrome, carcinoid teebmeem, tuaj yeem tshwm sim los ntawm kev phiv phais mob, tshuaj loog lossis tshuaj siv tshuaj kho mob.

Hu rau koj tus kws kho mob kom teem sijhawm yog tias koj muaj cov tsos mob ntawm carcinoid syndrome.

Kho cov qog ua kom txo qis cov mob carcinoid syndrome.

Dej ntws yaug syndrome; Argentaffinoma syndrome

• Serotonin kev siab

Lub koom haum Cancer National website. Kev kho tus mob plab hnyuv taum carcinoid hlav kho (Cov neeg laus) (PDQ) - kev noj qab haus huv tshaj tawm. www.cancer.gov/types/gi-carcinoid-tumors/hp/gi-carcinoid-nyuj-pdq. Hloov kho Cuaj hlis 16, 2020. Nkag mus siv Lub Kaum Hli 14, 2020.

Tumberg K. Neuroendocrine hlav thiab cuam tshuam rau lwm yam. Hauv: Melmed S, Auchus, RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Phau Ntawv ntawm Endocrinology. Xab 14th. Philadelphia, PA: Elsevier; 2020: chap 45.

Wolin EM, Jensen RT. Cov hlav hlav neuroendocrine. Hauv: Goldman L, Schafer AI, eds. Goldman-Cecil Tshuaj. 26th ed. Philadelphia, PA: Elsevier; 2020: cha 219.